Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness (Q41991320)

14 October 2017

Virally delivered channelrhodopsin-2 safely and effectively restores visual function in multiple mouse models of blindness (English)

1 reference

14 October 2017

5

Edward S Boyden

1 reference

14 October 2017

M Mehdi Doroudchi

1

1 reference

14 October 2017

Kenneth P Greenberg

2

1 reference

14 October 2017

Jianwen Liu

3

1 reference

14 October 2017

Kimberly A Silka

4

1 reference

14 October 2017

Jennifer A Lockridge

6

1 reference

14 October 2017

A Cyrus Arman

7

1 reference

14 October 2017

Ramesh Janani

8

1 reference

14 October 2017

Shannon E Boye

9

1 reference

14 October 2017

Sanford L Boye

10

1 reference

14 October 2017

Gabriel M Gordon

11

1 reference

14 October 2017

Benjamin C Matteo

12

1 reference

14 October 2017

Alapakkam P Sampath

13

1 reference

14 October 2017

William W Hauswirth

14

1 reference

14 October 2017

Alan Horsager

15

1 reference

14 October 2017

19 April 2011

1 reference

14 October 2017

1 reference

14 October 2017

19

1 reference

14 October 2017

1220-1229

1 reference

14 October 2017

7

1 reference

Cone photoreceptors are the main targets for gene therapy of NPHP5 (IQCB1) or NPHP6 (CEP290) blindness: generation of an all-cone Nphp6 hypomorph mouse that mimics the human retinal ciliopathy

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Temporal interactions during paired-electrode stimulation in two retinal prosthesis subjects

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Melanopsin-expressing retinal ganglion-cell photoreceptors: cellular diversity and role in pattern vision

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Spatiotemporal interactions in retinal prosthesis subjects

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Predicting visual sensitivity in retinal prosthesis patients

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Restoration of visual function in retinal degeneration mice by ectopic expression of melanopsin.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Factors affecting perceptual thresholds in epiretinal prostheses

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Effect of gene therapy on visual function in Leber's congenital amaurosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Neural reprogramming in retinal degeneration.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Organotypic culture of physiologically functional adult mammalian retinas

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Perspective on genes and mutations causing retinitis pigmentosa

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Millisecond-timescale, genetically targeted optical control of neural activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Adeno-associated virus-vectored gene therapy for retinal disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Temporal integration of intracellular Ca2+ signaling networks in regulating gene expression by action potentials

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

The mouse light/dark box test

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Channelrhodopsin-1: a light-gated proton channel in green algae.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Animal models in research on retinal degenerations: past progress and future hope

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

In vivo electroporation: a powerful and convenient means of nonviral gene transfer to tissues of living animals (Review).

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Apoptotic cell death in retinal degenerations.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Immune privilege, T-cell tolerance, and tissue-restricted autoimmunity.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Differential targeting of optical neuromodulators to ganglion cell soma and dendrites allows dynamic control of center-surround antagonism

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Subretinal electronic chips allow blind patients to read letters and combine them to words.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Visual function in mice with photoreceptor degeneration and transgenic expression of channelrhodopsin 2 in ganglion cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Evaluation of the adeno-associated virus mediated long-term expression of channelrhodopsin-2 in the mouse retina

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Cone contacts, mosaics, and territories of bipolar cells in the mouse retina.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Retinal ganglion cells survive and maintain normal dendritic morphology in a mouse model of inherited photoreceptor degeneration.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Cellular responses to photoreceptor death in the rd1 mouse model of retinal degeneration.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Parallel processing in retinal ganglion cells: how integration of space-time patterns of excitation and inhibition form the spiking output

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Optokinetic test to evaluate visual acuity of each eye independently

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Causes and prevalence of visual impairment among adults in the United States

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Retinal remodeling triggered by photoreceptor degenerations.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Vertical interactions across ten parallel, stacked representations in the mammalian retina

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Elevated dark-adapted thresholds in hypopigmented mice measured with a water maze screening apparatus.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Changes in the maintained discharge with adaptation level in the cat retina

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129568

Specific aqueous humor factors induce activation of regulatory T cells

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21505421

12 December 2020

inferred from PubMed ID database lookup

The response properties of the steady antagonistic surround in the mudpuppy retina

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21505421

12 December 2020

inferred from PubMed ID database lookup

Accumulation of glial fibrillary acidic protein in Müller radial glia during retinal degeneration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21505421

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/MT.2011.69

1 reference

release_sjxmtqbmwvboriomc7blc7bfvy

14 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sjxmtqbmwvboriomc7blc7bfvy

24 November 2022

mapped directly with Wikidata item

1 reference

14 October 2017

1 reference