Apoptotic signalling cascade in photosensitized human epidermal carcinoma A431 cells: involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2. (Q41957355)

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scientific article published on October 2000

Language	Label	Description	Also known as
English	Apoptotic signalling cascade in photosensitized human epidermal carcinoma A431 cells: involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2.	scientific article published on October 2000

Statements

scholarly article

1 reference

Europe PubMed Central

14 October 2017

Apoptotic signalling cascade in photosensitized human epidermal carcinoma A431 cells: involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2. (English)

1 reference

Europe PubMed Central

14 October 2017

apoptotic process

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author name string

Chan WH

1

1 reference

Europe PubMed Central

14 October 2017

Yu JS

2

1 reference

Europe PubMed Central

14 October 2017

Yang SD

3

1 reference

Europe PubMed Central

14 October 2017

language of work or name

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publication date

1 October 2000

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Europe PubMed Central

14 October 2017

number of pages

12

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based on heuristic

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Biochemical Journal

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Europe PubMed Central

14 October 2017

351

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Europe PubMed Central

14 October 2017

221-232

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Europe PubMed Central

14 October 2017

Pt 1

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Europe PubMed Central

14 October 2017

Emerging from the Pak: the p21-activated protein kinase family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

PAK2 is cleaved and activated during hyperosmotic shock-induced apoptosis via a caspase-dependent mechanism: evidence for the involvement of oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Activation of JNK and p38 but not ERK MAP kinases in human skin cells by 5-aminolevulinate-photodynamic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Proteolytic cleavage and activation of PAK2 during UV irradiation-induced apoptosis in A431 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Identification of the regulatory autophosphorylation site of autophosphorylation-dependent protein kinase (auto-kinase). Evidence that auto-kinase belongs to a member of the p21-activated kinase family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Photodynamic therapy results in induction of WAF1/CIP1/P21 leading to cell cycle arrest and apoptosis

1 reference

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5 June 2018

Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis

1 reference

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5 June 2018

Determination of singlet oxygen-specific versus radical-mediated lipid peroxidation in photosensitized oxidation of lipid bilayers: effect of beta-carotene and alpha-tocopherol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Caspases: killer proteases

1 reference

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5 June 2018

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Kinase cascades regulating entry into apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

A novel human SPS1/STE20 homologue, KHS, activates Jun N-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis

1 reference

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5 June 2018

Stimulation of stress-activated protein kinase and p38 HOG1 kinase in murine keratinocytes following photodynamic therapy with benzoporphyrin derivative

1 reference

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5 June 2018

Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway

1 reference

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5 June 2018

Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade

1 reference

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5 June 2018

Newly identified stress-responsive protein kinases, Krs-1 and Krs-2

1 reference

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5 June 2018

Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members

1 reference

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5 June 2018

Molecular cloning and sequencing of the cytostatic G protein-activated protein kinase PAK I.

1 reference

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5 June 2018

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

1 reference

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5 June 2018

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

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5 June 2018

Apoptosis during photodynamic therapy-induced ablation of RIF-1 tumors in C3H mice: electron microscopic, histopathologic and biochemical evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

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5 June 2018

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

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5 June 2018

Photodynamic therapy with photofrin II induces programmed cell death in carcinoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

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5 June 2018

CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Apoptosis in the pathogenesis and treatment of disease

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5 June 2018

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

1 reference

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5 June 2018

Tyrosine dephosphorylation and concurrent inactivation of protein kinase FA/GSK-3 alpha by genistein in A431 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20

1 reference

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5 June 2018

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

1 reference

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5 June 2018

Singlet oxygen: a primary effector in the ultraviolet A/near-visible light induction of the human heme oxygenase gene.

1 reference

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5 June 2018

Activation of mitogen-activated protein kinase cascades by p21-activated protein kinases in cell-free extracts of Xenopus oocytes.

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5 June 2018

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

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5 June 2018

Identification of a mouse p21Cdc42/Rac activated kinase

1 reference

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5 June 2018

Okadaic acid, a serine/threonine phosphatase inhibitor, induces tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3 alpha in A431 cells

1 reference

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5 June 2018

Protein kinase FA/glycogen synthase kinase-3 predominantly phosphorylates the in vivo site Thr97-Pro in brain myelin basic protein: evidence for Thr-Pro and Ser-Arg-X-X-Ser as consensus sequence motifs.

1 reference

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5 June 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

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5 June 2018

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221353

5 June 2018

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1 reference

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5 June 2018

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

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5 June 2018

Properties and applications of photodynamic therapy.

1 reference

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5 June 2018

Drug and chemical photosensitivity

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5 June 2018

How does photodynamic therapy work?

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5 June 2018

Activation of stress-activated protein kinase/c-Jun NH2-terminal kinase and p38 kinase in calphostin C-induced apoptosis requires caspase-3-like proteases but is dispensable for cell death.

1 reference

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18 August 2018

Heat shock stress induces cleavage and activation of PAK2 in apoptotic cells

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18 August 2018

Promotion of photodynamic therapy-induced apoptosis by stress kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10998365

12 December 2020

based on heuristic

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Protease activation and cleavage of poly(ADP-ribose) polymerase: an integral part of apoptosis in response to photodynamic treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/10998365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis: alive and kicking in 1997

1 reference

https://pubmed.ncbi.nlm.nih.gov/10998365

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based on heuristic

inferred from PubMed ID database lookup

The photobiology of photodynamic therapy: cellular targets and mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/10998365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid cytochrome c release, activation of caspases 3, 6, 7 and 8 followed by Bap31 cleavage in HeLa cells treated with photodynamic therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10998365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

1 reference

https://pubmed.ncbi.nlm.nih.gov/10998365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Activation of the c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase Signaling Pathways Protects HeLa Cells from Apoptosis Following Photodynamic Therapy with Hypericin

1 reference

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Phospholipase activation triggers apoptosis in photosensitized mouse lymphoma cells

1 reference

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Singlet oxygen mediates the activation of JNK by UVA radiation in human skin fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10998365

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based on heuristic

inferred from PubMed ID database lookup

Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells

1 reference

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based on heuristic

inferred from PubMed ID database lookup

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

1 reference

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inferred from PubMed ID database lookup

c-Jun NH2-terminal kinase-mediated activation of interleukin-1beta converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis

1 reference

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based on heuristic

inferred from PubMed ID database lookup

p21-activated kinase (PAK) is required for Fas-induced JNK activation in Jurkat cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10998365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of an S6/H4 kinase (PAK 65) from human placenta by intramolecular and intermolecular autophosphorylation

1 reference

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inferred from PubMed ID database lookup

Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism

1 reference

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Ceramide generation in response to photodynamic treatment of L5178Y mouse lymphoma cells

1 reference

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Identifiers

10.1042/0264-6021:3510221

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Europe PubMed Central

14 October 2017

release_xsmgexgkb5bnzntx6ziewydy74

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https://api.fatcat.wiki/v0/release/xsmgexgkb5bnzntx6ziewydy74

24 November 2022

based on heuristic

mapped directly with Wikidata item

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Europe PubMed Central

14 October 2017

1 reference

Europe PubMed Central

14 October 2017

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