Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age. (Q41953858)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Kosta Steliou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Walter H. Moos

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

author name string

Douglas V Faller

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Michael H Irwin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

language of work or name

1 reference

1 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

Drug Development Research

18 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

volume

76

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

page(s)

167-175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

Optimal micronutrients delay mitochondrial decay and age-associated diseases

18 February 2020

cites work

1 reference

Epigenetic regulation of self-renewal and fate determination in neural stem cells

21 January 2018

1 reference

The pathways of mitophagy for quality control and clearance of mitochondria

21 January 2018

1 reference

Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases--a mechanistic approach

21 January 2018

1 reference

The pharmacology of the antioxidant lipoic acid

21 January 2018

1 reference

Enhancement of memory consolidation by the histone deacetylase inhibitor sodium butyrate in aged rats

21 January 2018

1 reference

Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models

21 January 2018

1 reference

Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications.

21 January 2018

1 reference

The epigenetic effects of butyrate: potential therapeutic implications for clinical practice

21 January 2018

1 reference

Mitochondrially-imported RNA in drug discovery

21 January 2018

1 reference

Cofactor regeneration for enzyme-catalysed synthesis

21 January 2018

1 reference

Short-term and long-term health risks of nuclear-power-plant accidents

21 January 2018

1 reference

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

21 January 2018

1 reference

Safety evaluation of alpha-lipoic acid (ALA).

21 January 2018

1 reference

Long-term safety of alpha-lipoic acid (ALA) consumption: A 2-year study.

21 January 2018

1 reference

Dietary histone deacetylase inhibitors: from cells to mice to man

21 January 2018

1 reference

In vitro ischemia decreases histone H4K16 acetylation in neural cells.

21 January 2018

1 reference

Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis

21 January 2018

1 reference

α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects

21 January 2018

1 reference

Autophagy and neurodegeneration

21 January 2018

1 reference

Mitochondrial form and function

21 January 2018

1 reference

High doses of the histone deacetylase inhibitor sodium butyrate trigger a stress-like response

21 January 2018

1 reference

Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents

21 January 2018

1 reference

Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases

21 January 2018

1 reference

Lipoic acid - biological activity and therapeutic potential

21 January 2018

1 reference

HDAC2 negatively regulates memory formation and synaptic plasticity.

21 January 2018

1 reference

Epigenetic targeting of histone deacetylase: therapeutic potential in Parkinson's disease?

21 January 2018

1 reference

Enantioselective pharmacokinetics and bioavailability of different racemic α-lipoic acid formulations in healthy volunteers

21 January 2018

1 reference

Identification and functional expression of the mitochondrial pyruvate carrier

21 January 2018

1 reference

Mouse models of mitochondrial complex I dysfunction

21 January 2018

1 reference

Iodide protects heart tissue from reperfusion injury

21 January 2018

1 reference

Age and gender dependent bioavailability of R- and R,S-α-lipoic acid: a pilot study

21 January 2018

1 reference

The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain

21 January 2018

1 reference

Effects of alpha-lipoic Acid on body weight in obese subjects

21 January 2018

1 reference

Histone deacetylase inhibitor: antineoplastic agent and radiation modulator

21 January 2018

1 reference

Mitochondrial dysfunction in Gulf War illness revealed by 31Phosphorus Magnetic Resonance Spectroscopy: a case-control study.

21 January 2018

1 reference

Differential effects of short-chain fatty acids on head and neck squamous carcinoma cells

21 January 2018

1 reference

Chemoprevention of rat hepatocarcinogenesis with histone deacetylase inhibitors: efficacy of tributyrin, a butyric acid prodrug.

21 January 2018

1 reference

Gut microbiota-generated metabolites in animal health and disease

21 January 2018

1 reference

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

21 January 2018

1 reference

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid

21 January 2018

1 reference

Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain

21 January 2018

1 reference

Small molecules and small molecule drugs in regenerative medicine

21 January 2018

1 reference

Histone deacetylases and mood disorders: epigenetic programming in gene-environment interactions

21 January 2018

1 reference

The therapeutic uses of chromatin-modifying agents

21 January 2018

1 reference

Memory impairment, oxidative damage and apoptosis induced by space radiation: ameliorative potential of alpha-lipoic acid

21 January 2018

1 reference

Radiation-induced cognitive dysfunction and cerebellar oxidative stress in mice: protective effect of alpha-lipoic acid.

21 January 2018

1 reference

Lipoic acid biosynthesis defects.

21 January 2018

1 reference

A randomized phase II trial of Arginine Butyrate with standard local therapy in refractory sickle cell leg ulcers

21 January 2018

1 reference

Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease

21 January 2018

1 reference

Cellular and physiological effects of short-chain fatty acids

21 January 2018

1 reference

Mitochondrial dynamics and inheritance during cell division, development and disease

21 January 2018

1 reference

Mitochondrial drugs come of age.

21 January 2018

1 reference

Radiation Drugs-Still a Hot Topic

21 January 2018

1 reference

Radiation Drugs-A Hot Topic

21 January 2018

1 reference

Carnitine: transport and physiological functions in the brain.

21 January 2018

1 reference

Autophagy in the physiology and pathology of the central nervous system

21 January 2018

1 reference

Mitophagy: a complex mechanism of mitochondrial removal

21 January 2018

1 reference

Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice

21 January 2018

1 reference

Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo

21 January 2018

1 reference

Mitochondrial homeostasis: the interplay between mitophagy and mitochondrial biogenesis

21 January 2018

1 reference

D-galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice

21 January 2018

1 reference

Protection by an antioxidant of rotenone-induced neuromotor decline, reactive oxygen species generation and cellular stress in mouse brain.

21 January 2018

1 reference

Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex I inhibition.

21 January 2018

1 reference

Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist.

21 January 2018

1 reference

Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection

21 January 2018

1 reference

Fetal globin induction--can it cure beta thalassemia?

21 January 2018

1 reference

A phase 1/2 trial of arginine butyrate and ganciclovir in patients with Epstein-Barr virus-associated lymphoid malignancies

21 January 2018

1 reference

Erythroid Kruppel-like factor (EKLF) is recruited to the gamma-globin gene promoter as a co-activator and is required for gamma-globin gene induction by short-chain fatty acid derivatives

21 January 2018

1 reference

Mitophagy mechanisms and role in human diseases

21 January 2018

1 reference

Small-molecule targeting of the mitochondrial compartment with an endogenously cleaved reversible tag.

21 January 2018

1 reference

Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease

21 January 2018

1 reference

Probiotic in lamb rennet paste enhances rennet lipolytic activity, and conjugated linoleic acid and linoleic acid content in Pecorino cheese

21 January 2018

1 reference

Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre

21 January 2018

1 reference

Autophagy and human disease: emerging themes

21 January 2018

1 reference

Alzheimer's disease and epigenetic diet.

21 January 2018

1 reference

Evaluating the toxicity of novel Zn-DTPA tablet formulation in dogs and rats.

21 January 2018

1 reference

The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease

21 January 2018

1 reference

Mitochondrial pharmacology

21 January 2018

1 reference

Mitochondria-targeted small molecule therapeutics and probes

21 January 2018

1 reference

Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+)

21 January 2018

1 reference

The pyruvate dehydrogenase complex as a therapeutic target for age-related diseases

21 January 2018

1 reference

Beyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial health

21 January 2018

1 reference

Butyrate histone deacetylase inhibitors.

21 January 2018

1 reference

Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications

21 January 2018

1 reference

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

21 January 2018

1 reference

A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation

21 January 2018

1 reference

High-performance liquid chromatographic assay for alpha-lipoic acid and five of its metabolites in human plasma and urine

21 January 2018

1 reference

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease

21 January 2018

1 reference

The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: a review

21 January 2018

1 reference

Alpha-lipoic acid induces p27Kip-dependent cell cycle arrest in non-transformed cell lines and apoptosis in tumor cell lines.

21 January 2018

1 reference

Effects of alpha-lipoic acid on associative and spatial memory of sham-irradiated and 56Fe-irradiated C57BL/6J male mice

21 January 2018

1 reference

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

21 January 2018

1 reference

Mitochondrial alteration in malignantly transformed human small airway epithelial cells induced by α-particles

21 January 2018

1 reference

Pink1, the first ubiquitin kinase

21 January 2018

1 reference

Overview of the Classical Histone Deacetylase Enzymes and Histone Deacetylase Inhibitors

21 January 2018

1 reference

Targeting lipoic acid to mitochondria: synthesis and characterization of a triphenylphosphonium-conjugated alpha-lipoyl derivative

21 January 2018

1 reference

7 January 2021

HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3

1 reference

7 January 2021

A mitochondrial expatriate: nuclear pyruvate dehydrogenase

1 reference

7 January 2021

Protection against genotoxic damages following whole body gamma radiation exposure in mice by lipoic acid

1 reference

7 January 2021

Identifiers

DOI

10.1002/DDR.21258

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26109467%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference