Integrin αIIbβ3 inside-out activation: an in situ conformational analysis reveals a new mechanism (Q41952463)

14 October 2017

Integrin αIIbβ3 inside-out activation: an in situ conformational analysis reveals a new mechanism (English)

1 reference

14 October 2017

3

Debra Newman

1 reference

14 October 2017

Lisa Kurtz

1

1 reference

14 October 2017

Liyo Kao

series ordinal

2

1 reference

14 October 2017

Ira Kurtz

series ordinal

4

1 reference

14 October 2017

Quansheng Zhu

series ordinal

5

1 reference

14 October 2017

language of work or name

English

0 references

publication date

21 May 2012

1 reference

Journal of Biological Chemistry

14 October 2017

1 reference

14 October 2017

287

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14 October 2017

27

1 reference

14 October 2017

23255-23265

1 reference

Basic amino-acid side chains regulate transmembrane integrin signalling

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Multiscale simulations suggest a mechanism for integrin inside-out activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

The tail of integrin activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

NMR analysis of the IIb 3 cytoplasmic interaction suggests a mechanism for integrin regulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Structural and functional characterization of the C-terminal transmembrane region of NBCe1-A.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

The final steps of integrin activation: the end game

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Structure and hydration of membranes embedded with voltage-sensing domains

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Structure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

The tail of integrins, talin, and kindlins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Interactions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review).

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Kindlin-2 (Mig-2): a co-activator of beta3 integrins.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Structure of the Integrin IIb Transmembrane Segment

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Kindlin-3 is essential for integrin activation and platelet aggregation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Topology of transmembrane proteins by scanning cysteine accessibility mutagenesis methodology.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Structural basis of integrin activation by talin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Structural basis of integrin regulation and signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Membrane-mediated structural transitions at the cytoplasmic face during integrin activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Novel topology in C-terminal region of the human plasma membrane anion exchanger, AE1.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Integrins: bidirectional, allosteric signaling machines

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

A redox site involved in integrin activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

The conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding affinity.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Integrin cytoplasmic domains mediate inside-out signal transduction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

A coiled-coil structure of the alphaIIbbeta3 integrin transmembrane and cytoplasmic domains in its resting state

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391112

Preservation and staining of myelinated nerve fibers.

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.360966

Determination of the Border between the Transmembrane and Cytoplasmic Domains of Human Integrin Subunits

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.360966

Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22613710

12 December 2020

inferred from PubMed ID database lookup

Substituted-cysteine accessibility method

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22613710

12 December 2020

inferred from PubMed ID database lookup

The inner world of cell adhesion: integrin cytoplasmic domains

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22613710

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M112.360966

1 reference

release_eh4ptlz45bae5f3halcsfj5liy

14 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/eh4ptlz45bae5f3halcsfj5liy

24 November 2022

mapped directly with Wikidata item

1 reference

14 October 2017

1 reference