Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation. (Q41936018)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969955%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation (English)

1 reference

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8 March 2020

2

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8 March 2020

Matthew Freeman

5

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8 March 2020

author name string

Yonka Christova

1

1 reference

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8 March 2020

Paul Bambrough

3

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8 March 2020

Ashraf Ibrahim

4

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8 March 2020

publication date

23 August 2013

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8 March 2020

1 reference

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8 March 2020

volume

14

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8 March 2020

issue

10

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8 March 2020

page(s)

884-890

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Sampling the membrane: function of rhomboid-family proteins

8 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

iRHOM2 is a critical pathogenic mediator of inflammatory arthritis

5 June 2018

1 reference

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New lives for old: evolution of pseudoenzyme function illustrated by iRhoms.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

iRhom2 is required for the secretion of mouse TNFα

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Chromosome 17q25 genes, RHBDF2 and CYGB, in ovarian cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE

5 June 2018

1 reference

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Multiple Loci modulate opioid therapy response for cancer pain

5 June 2018

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Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling

5 June 2018

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The "A Disintegrin And Metalloproteases" ADAM10 and ADAM17: novel drug targets with therapeutic potential?

5 June 2018

1 reference

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G protein-coupled receptors: novel targets for drug discovery in cancer

5 June 2018

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The lack of ADAM17 activity during embryonic development causes hemorrhage and impairs vessel formation

5 June 2018

1 reference

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EGF receptor activation by GPCRs: an universal pathway reveals different versions

5 June 2018

1 reference

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ADAM-17: the enzyme that does it all.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Deficiency of TNFalpha converting enzyme (TACE/ADAM17) causes a lean, hypermetabolic phenotype in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

ADAMs: key components in EGFR signalling and development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE)

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807218

Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer

5 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOR.2013.128

An essential role for ectodomain shedding in mammalian development

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23969955

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOR.2013.128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969955%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

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8 March 2020

PubMed publication ID

23969955

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23969955%20AND%20SRC:MED&resulttype=core&format=json