Cochlear pharmacokinetics with local inner ear drug delivery using a three-dimensional finite-element computer model. (Q41931676)

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22 December 2019

title

Cochlear pharmacokinetics with local inner ear drug delivery using a three-dimensional finite-element computer model (English)

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22 December 2019

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2

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22 December 2019

Raimund Wegener

3

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22 December 2019

Alec N. Salt

5

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22 December 2019

author name string

Stefan K Plontke

1

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22 December 2019

Hans-Peter Zenner

4

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22 December 2019

publication date

17 November 2006

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Audiology and Neuro-Otology

22 December 2019

published in

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22 December 2019

volume

12

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22 December 2019

issue

1

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22 December 2019

page(s)

37-48

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Demonstration of a longitudinal concentration gradient along scala tympani by sequential sampling of perilymph from the cochlear apex.

22 December 2019

cites work

1 reference

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Perilymph sampling from the cochlear apex: a reliable method to obtain higher purity perilymph samples from scala tympani.

5 June 2018

1 reference

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Local inner-ear drug delivery and pharmacokinetics.

5 June 2018

1 reference

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Outcomes research analysis of continuous intratympanic glucocorticoid delivery in patients with acute severe to profound hearing loss: basis for planning randomized controlled trials.

5 June 2018

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Ablation therapy for the relief of Ménière's disease

5 June 2018

1 reference

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Targeted topical steroid therapy in sudden sensorineural hearing loss

5 June 2018

1 reference

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Preliminary results of a new delivery system for gentamicin to the inner ear in patients with Meniere's disease

5 June 2018

1 reference

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Three-dimensional numerical modeling for global cochlear dynamics.

5 June 2018

1 reference

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Finite element modeling of drug distribution in the vitreous humor of the rabbit eye.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Aerodynamic effects of inferior turbinate reduction: computational fluid dynamics simulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Communication between the perilymphatic scalae and spiral ligament visualized by in vivo MRI.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Effectiveness of intratympanic dexamethasone injection in sudden-deafness patients as salvage treatment

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Surface microstructure of the perilymphatic space: implications for cochlear implants and cell- or drug-based therapies.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

1D-and 3D- computer simulation for experimental planning and interpretation of pharmacokinetic studies in the inner ear after local drug delivery

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Transtympanic injection of anesthetics for the treatment of Méniére's syndrome.

18 August 2018

1 reference

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Quantitative interpretation of corticosteroid pharmacokinetics in inner fluids using computer simulations.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Contamination of perilymph sampled from the basal cochlear turn with cerebrospinal fluid.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Analysis of gentamicin kinetics in fluids of the inner ear with round window administration

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Simulation of methods for drug delivery to the cochlear fluids

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Quantification of solute entry into cochlear perilymph through the round window membrane

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Continuous intratympanic infusion of gentamicin via a microcatheter in Menière's disease

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Cochlear fluid space dimensions for six species derived from reconstructions of three-dimensional magnetic resonance images.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

27 years experiences with transtympanic aminoglycoside treatment of Menière's disease

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779502

Modelling of components of the human middle ear and simulation of their dynamic behaviour

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17119332

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interpretation of endolymph flow results: a comment on 'Longitudinal flow of endolymph measured by distribution of tetraethylammonium and choline in scala media'

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17119332

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1159/000097246

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17119332%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17119332%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

PubMed publication ID

17119332

1 reference