Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size (Q41930126)

14 October 2017

Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size (English)

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14 October 2017

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Jonathan Wilde

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Lee Niswander

object named as

Lee Niswander

6

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author name string

Jian-Fu Chen

1

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14 October 2017

Ying Zhang

2

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14 October 2017

Kirk C Hansen

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14 October 2017

Fan Lai

5

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14 October 2017

language of work or name

English

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publication date

30 May 2014

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14 October 2017

Nature Communications

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14 October 2017

5

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14 October 2017

3885

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https://scigraph.springernature.com/pub.10.1038/ncomms4885

14 October 2017

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cites work

Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation

1 reference

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WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression

5 June 2018

1 reference

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Mutations in WDR62 gene in Pakistani families with autosomal recessive primary microcephaly

5 June 2018

1 reference

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MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Docking interactions of the JNK scaffold protein WDR62.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Cdk5rap2 exposes the centrosomal root of microcephaly syndromes

5 June 2018

1 reference

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Neural stem cells: historical perspective and future prospects.

5 June 2018

1 reference

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Spindle poisons and cell fate: a tale of two pathways.

5 June 2018

1 reference

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WDR62 is associated with the spindle pole and is mutated in human microcephaly

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture

5 June 2018

1 reference

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Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations

5 June 2018

1 reference

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An alternative splicing network links cell-cycle control to apoptosis

5 June 2018

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CDK5RAP2 regulates centriole engagement and cohesion in mice

5 June 2018

1 reference

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Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors

5 June 2018

1 reference

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BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice

5 June 2018

1 reference

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A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Primary microcephaly: do all roads lead to Rome?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

The glial nature of embryonic and adult neural stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Aurora-A kinase is essential for bipolar spindle formation and early development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Mechanisms of mitotic spindle assembly and function

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

The spindle-assembly checkpoint in space and time

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Molecular genetic determinants of human brain size

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Evolution of the brain and intelligence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Aurora-A - a guardian of poles

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Mitotic spindle regulation by Nde1 controls cerebral cortical size

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Citron kinase is a regulator of mitosis and neurogenic cytokinesis in the neocortical ventricular zone

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Centrosome aberrations: cause or consequence of cancer progression?

5 June 2018

1 reference

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Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Metaphase spindles rotate in the neuroepithelium of rat cerebral cortex.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

The structure of the cold-stable kinetochore fiber in metaphase PtK1 cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Tpx2 controls spindle integrity, genome stability, and tumor development.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Mitotic catastrophe: a mechanism for avoiding genomic instability.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

Stem and progenitor cell-based therapy of the human central nervous system.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216695

18 August 2018

Identifiers

DOI

10.1038/NCOMMS4885

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14 October 2017

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14 October 2017

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