Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent but caspase-independent (Q41918709)

14 October 2017

Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent but caspase-independent (English)

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14 October 2017

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Korsmeyer SJ

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14 October 2017

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Flavell RA

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14 October 2017

Zaidi AU

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14 October 2017

McDonough JS

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14 October 2017

Klocke BJ

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14 October 2017

Latham CB

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14 October 2017

Schmidt RE

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Roth KA

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1 October 2001

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Journal of Neuropathology & Experimental Neurology

14 October 2017

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14 October 2017

60

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14 October 2017

937-945

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The morphology of various types of cell death in prenatal tissues

14 October 2017

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Developmental cell death: morphological diversity and multiple mechanisms

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Protein breakdown. Ubiquitous déjà vu.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Caspase-independent programmed cell death with necrotic morphology

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Autophagy and other vacuolar protein degradation mechanisms

21 January 2018

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Autophagy and related mechanisms of lysosome-mediated protein degradation

21 January 2018

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Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole

21 January 2018

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A protein conjugation system essential for autophagy

21 January 2018

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Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells.

21 January 2018

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Molecular dissection of autophagy: two ubiquitin-like systems

21 January 2018

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Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization

21 January 2018

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Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Degeneration of neuronal processes in rats induced by a protease inhibitor, leupeptin

21 January 2018

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Abnormal distribution of cathepsins in the brain of patients with Alzheimer's disease

21 January 2018

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Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system.

21 January 2018

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Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Death associated proteins (DAPs): from gene identification to the analysis of their apoptotic and tumor suppressive functions.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

An alternative, nonapoptotic form of programmed cell death

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Commentary. Lysosomotropic agents

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Chloroquine myopathy suggests that tau is degraded in lysosomes: implication for the formation of paired helical filaments in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Accumulation of tau in autophagic vacuoles in chloroquine myopathy

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Lysosomal protease inhibitors induce meganeurites and tangle-like structures in entorhinohippocampal regions vulnerable to Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Trophic support promotes survival of bcl-x-deficient telencephalic cells in vitro

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Neurotrophin sensitivity of prevertebral and paravertebral rat sympathetic autonomic ganglia.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

The role of p53 in neuronal cell death

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Caspase requirement for neuronal apoptosis and neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Apoptosis and Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Involvement of caspase 3 in apoptotic death of cortical neurons evoked by DNA damage.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Mechanisms of programmed cell death in the developing brain

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

Neuronal life and death: an essential role for the p53 family

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F60.10.937

21 January 2018

Identifiers

DOI

10.1093/JNEN/60.10.937

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14 October 2017

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