Silver Nanoparticle-Induced Autophagic-Lysosomal Disruption and NLRP3-Inflammasome Activation in HepG2 Cells Is Size-Dependent (Q41915909)

14 October 2017

Silver Nanoparticle-Induced Autophagic-Lysosomal Disruption and NLRP3-Inflammasome Activation in HepG2 Cells Is Size-Dependent (English)

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14 October 2017

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Anurag R Mishra

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14 October 2017

Jiwen Zheng

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2

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14 October 2017

Xing Tang

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3

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14 October 2017

Peter L Goering

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4

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14 October 2017

21 January 2016

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14 October 2017

Toxicological Sciences

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14 October 2017

150

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14 October 2017

473-487

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14 October 2017

2

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Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models

14 October 2017

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Silver nanoparticle applications and human health

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Persistence of silver nanoparticles in the rat lung: influence of dose, size, and chemical composition

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Mechanistic study on the biological effects of silver and gold nanoparticles in Caco-2 cells--induction of the Nrf2/HO-1 pathway by high concentrations of silver nanoparticles

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats.

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Autophagy: assays and artifacts

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Lysosomal membrane permeabilization in cell death

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Dynamic characteristics of silver nanoparticles in physiological fluids: toxicological implications

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Silver as antibacterial agent: ion, nanoparticle, and metal

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes.

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Caspase-1: is IL-1 just the tip of the ICEberg?

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Lysosomal membrane permeabilization by targeted magnetic nanoparticles in alternating magnetic fields

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

21 January 2018

Lysosomes in cell death

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Autophagy and human diseases

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Antimicrobial effects of silver nanoparticles.

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

The kinetics of the tissue distribution of silver nanoparticles of different sizes.

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Activation and regulation of the inflammasomes

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Interference in autophagosome fusion by rare earth nanoparticles disrupts autophagic flux and regulation of an interleukin-1β producing inflammasome.

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Toxic potential of materials at the nanolevel

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Investigating oxidative stress and inflammatory responses elicited by silver nanoparticles using high-throughput reporter genes in HepG2 cells: effect of size, surface coating, and intracellular uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Antibacterial effects of silver nanoparticles on gram-negative bacteria: influence on the growth and biofilms formation, mechanisms of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Silver nanoparticles induce degradation of the endoplasmic reticulum stress sensor activating transcription factor-6 leading to activation of the NLRP-3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Induction of autophagy in porcine kidney cells by quantum dots: a common cellular response to nanomaterials?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Subchronic inhalation toxicity of silver nanoparticles.

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Assessment of total silver and silver nanoparticle extraction from medical devices.

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Lysosomes integrate metabolic-inflammatory cross-talk in primary macrophage inflammasome activation

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Biodistribution of co-exposure to multi-walled carbon nanotubes and nanodiamonds in mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFW011

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFW011

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14 October 2017

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