Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches (Q41910335)

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scientific article published on September 2010

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English	Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches	scientific article published on September 2010

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scholarly article

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10 February 2020

Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches (English)

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10 February 2020

Archaeoglobus fulgidus

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Archaeoglobus fulgidus

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inferred from title

1

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10 February 2020

author name string

Anthony A Sauve

2

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1 September 2010

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10 February 2020

Journal of the American Chemical Society

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10 February 2020

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10 February 2020

35

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10 February 2020

12286-12298

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10 February 2020

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Transition State Structure for the Hydrolysis of NAD Catalyzed by Diphtheria Toxin

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Enzymatic transition state theory and transition state analogue design

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Sir2 deacetylases exhibit nucleophilic participation of acetyl-lysine in NAD+ cleavage.

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Transition-state analysis of S. pneumoniae 5'-methylthioadenosine nucleosidase

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Transition-state structure of human 5'-methylthioadenosine phosphorylase

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Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

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SIRT1 and endocrine signaling

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Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

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Calorie restriction--the SIR2 connection

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Enzymatic transition states: thermodynamics, dynamics and analogue design

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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Crystal structure of a SIR2 homolog-NAD complex

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Identifiers

10.1021/JA910342D

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10 February 2020

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10 February 2020

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10 February 2020

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