Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens. (Q41908299)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19794038%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19794038%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

6

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8 February 2020

1

M A Pfaller

1 reference

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8 February 2020

author name string

S A Messer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19794038%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

N Georgopapadakou

3

1 reference

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8 February 2020

L A Martell

4

1 reference

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8 February 2020

J M Besterman

5

1 reference

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8 February 2020

language of work or name

English

0 references

publication date

30 September 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19794038%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Microbiology

8 February 2020

published in

1 reference

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8 February 2020

volume

47

1 reference

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8 February 2020

issue

12

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8 February 2020

page(s)

3797-3804

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Multilaboratory testing of antifungal combinations against a quality control isolate of Candida krusei

8 February 2020

cites work

1 reference

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Potent antimalarial activity of histone deacetylase inhibitor analogues.

5 June 2018

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Will resistance in fungi emerge on a scale similar to that seen in bacteria?

5 June 2018

1 reference

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Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America

5 June 2018

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Recent advances and challenges in the treatment of invasive fungal infections

5 June 2018

1 reference

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Improved outcomes associated with advances in therapy for invasive fungal infections in immunocompromised hosts.

5 June 2018

1 reference

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Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans

5 June 2018

1 reference

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New agents for the treatment of fungal infections: clinical efficacy and gaps in coverage

5 June 2018

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Current treatment strategies for disseminated candidiasis

5 June 2018

1 reference

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Histone deacetylase inhibitors: latest developments, trends and prospects

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Emerging azole antifungals

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Combinations of antifungal agents in therapy--what value are they?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

History of the development of azole derivatives

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Histone deacetylase inhibitors: a new class of potential therapeutic agents for cancer treatment.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Deacetylase enzymes: biological functions and the use of small-molecule inhibitors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Acetylation of histones and transcription-related factors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Synergy of nitric oxide and azoles against Candida species in vitro.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Histone acetylation in chromatin structure and transcription

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Chemosensitization of fungal pathogens to antimicrobial agents using benzo analogs

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

In vitro interaction between azoles and cyclosporin A against clinical isolates of Candida albicans determined by the chequerboard method and time-kill curves

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Evaluation of Mycograb, amphotericin B, caspofungin, and fluconazole in combination against Cryptococcus neoformans by checkerboard and time-kill methodologies

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2786684

Guidelines for treatment of candidiasis

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19794038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Combination antifungal therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19794038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JCM.00618-09

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19794038%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19794038%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference