Contribution of Bcl-2 phosphorylation to Bak binding and drug resistance. (Q41906775)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24097825%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Contribution of Bcl-2 phosphorylation to Bak binding and drug resistance (English)

1 reference

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27 February 2020

1 reference

6

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27 February 2020

Haiming Dai

1

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27 February 2020

author name string

Husheng Ding

2

1 reference

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27 February 2020

X Wei Meng

3

1 reference

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27 February 2020

Sun-Hee Lee

4

1 reference

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27 February 2020

Paula A Schneider

5

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27 February 2020

language of work or name

English

0 references

publication date

4 October 2013

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27 February 2020

1 reference

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27 February 2020

volume

73

1 reference

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27 February 2020

issue

23

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27 February 2020

page(s)

6998-7008

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ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

27 February 2020

cites work

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5 June 2018

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A unified model of mammalian BCL-2 protein family interactions at the mitochondria.

5 June 2018

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Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

5 June 2018

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Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.

5 June 2018

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Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization

5 June 2018

1 reference

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Cytotoxicity of farnesyltransferase inhibitors in lymphoid cells mediated by MAPK pathway inhibition and Bim up-regulation.

5 June 2018

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Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL.

5 June 2018

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.

5 June 2018

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Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX

5 June 2018

1 reference

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Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells

5 June 2018

1 reference

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Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis

5 June 2018

1 reference

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The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins

5 June 2018

1 reference

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Context-dependent Bcl-2/Bak interactions regulate lymphoid cell apoptosis.

5 June 2018

1 reference

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Alteration of the mitochondrial apoptotic pathway is key to acquired paclitaxel resistance and can be reversed by ABT-737.

5 June 2018

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ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor

5 June 2018

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Overview of Biacore systems and their applications

5 June 2018

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Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.

5 June 2018

1 reference

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Methods for the detection and analysis of protein-protein interactions

5 June 2018

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

5 June 2018

1 reference

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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

5 June 2018

1 reference

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Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine

5 June 2018

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S-peptide epitope tagging for protein purification, expression monitoring, and localization in mammalian cells.

5 June 2018

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Components of the cell death machine and drug sensitivity of the National Cancer Institute Cell Line Panel.

5 June 2018

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Mono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functions

5 June 2018

1 reference

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G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells

5 June 2018

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Unwinding the loop of Bcl-2 phosphorylation

5 June 2018

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Phosphorylation of Bcl2 and regulation of apoptosis

5 June 2018

1 reference

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Solution structure of the antiapoptotic protein bcl-2

5 June 2018

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Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases

5 June 2018

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

5 June 2018

1 reference

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BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

5 June 2018

1 reference

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Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.

5 June 2018

1 reference

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

5 June 2018

1 reference

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Bcl-2 phosphorylation required for anti-apoptosis function

5 June 2018

1 reference

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Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

5 June 2018

1 reference

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Inactivation of Bcl-2 by phosphorylation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910374

Induction of apoptosis by the Bcl-2 homologue Bak

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910374

Measurement of protein using bicinchoninic acid

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910374

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910374

Navitoclax enhances the efficacy of taxanes in non-small cell lung cancer models

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910374

"Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910374

Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death.

18 August 2018

1 reference

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Reutilization of Immunoblots after Chemiluminescent Detection

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910374

Phosphorylation of Bcl-2 protein by CDC2 kinase during G2/M phases and its role in cell cycle regulation

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24097825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Serine-70 is one of the critical sites for drug-induced Bcl2 phosphorylation in cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24097825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24097825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-13-0940

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24097825%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24097825%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

24097825

1 reference