PEG length and chemical linkage controls polyacridine peptide DNA polyplex pharmacokinetics, biodistribution, metabolic stability and in vivo gene expression. (Q41895722)

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scientific article published on 2 June 2013

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English	PEG length and chemical linkage controls polyacridine peptide DNA polyplex pharmacokinetics, biodistribution, metabolic stability and in vivo gene expression.	scientific article published on 2 June 2013

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scholarly article

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2 March 2020

PEG length and chemical linkage controls polyacridine peptide DNA polyplex pharmacokinetics, biodistribution, metabolic stability and in vivo gene expression (English)

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2 March 2020

pharmacokinetics

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2 March 2020

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Sanjib Khargharia

1

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2 March 2020

Koby Kizzire

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2 March 2020

Nicholas J Baumhover

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2 March 2020

Kevin G Rice

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2 March 2020

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2 June 2013

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2 March 2020

Journal of Controlled Release

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2 March 2020

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2 March 2020

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2 March 2020

325-333

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2 March 2020

High-affinity PEGylated polyacridine peptide polyplexes mediate potent in vivo gene expression

1 reference

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5 June 2018

Effect of core diameter, surface coating, and PEG chain length on the biodistribution of persistent luminescence nanoparticles in mice

1 reference

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5 June 2018

Metabolically stabilized long-circulating PEGylated polyacridine peptide polyplexes mediate hydrodynamically stimulated gene expression in liver.

1 reference

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5 June 2018

N-glycan targeted gene delivery to the dendritic cell SIGN receptor

1 reference

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5 June 2018

Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides

1 reference

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5 June 2018

Control of the in vivo biodistribution of hybrid nanoparticles with different poly(ethylene glycol) coatings

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5 June 2018

Tissue- and organ-selective biodistribution of NIR fluorescent quantum dots

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5 June 2018

Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding

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5 June 2018

Extracellular barriers to in Vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver

1 reference

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5 June 2018

Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes

1 reference

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5 June 2018

Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions

1 reference

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5 June 2018

Barriers to gene delivery using synthetic vectors.

1 reference

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5 June 2018

PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice

1 reference

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5 June 2018

Hydroporation as the mechanism of hydrodynamic delivery

1 reference

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5 June 2018

Development of a nonviral gene delivery vehicle for systemic application

1 reference

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5 June 2018

PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904502

5 June 2018

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904502

5 June 2018

Biodistribution and gene expression of lipid/plasmid complexes after systemic administration

1 reference

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5 June 2018

Golgi fractions prepared from rat liver homogenates. I. Isolation procedure and morphological characterization

1 reference

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5 June 2018

Liposomes as targetable drug carriers

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904502

5 June 2018

Sterically stabilized liposomes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904502

5 June 2018

Ultrasound-enhanced transfection activity of HPMA-stabilized DNA polyplexes with prolonged plasma circulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904502

18 August 2018

Hydrodynamic liver gene transfer mechanism involves transient sinusoidal blood stasis and massive hepatocyte endocytic vesicles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904502

18 August 2018

Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904502

18 August 2018

Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer

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18 August 2018

Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation

1 reference

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18 August 2018

Cross-linked low molecular weight glycopeptide-mediated gene delivery: relationship between DNA metabolic stability and the level of transient gene expression in vivo

1 reference

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Biodistribution of long-circulating PEG-grafted nanocapsules in mice: effects of PEG chain length and density.

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18 August 2018

Biodistribution, metabolism, and in vivo gene expression of low molecular weight glycopeptide polyethylene glycol peptide DNA co-condensates

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18 August 2018

Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery

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18 August 2018

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

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18 August 2018

The fate of plasmid DNA after intravenous injection in mice: involvement of scavenger receptors in its hepatic uptake

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18 August 2018

Mechanism of plasmid delivery by hydrodynamic tail vein injection. II. Morphological studies

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12 December 2020

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inferred from PubMed ID database lookup

Effect of Poly(ethylene glycol) Length on the in Vivo Behavior of Coated Quantum Dots

1 reference

https://pubmed.ncbi.nlm.nih.gov/23735574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific effects of PEGylation on gene delivery efficacy of polyethylenimine: interplay between PEG substitution and N/P ratio

1 reference

https://pubmed.ncbi.nlm.nih.gov/23735574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake by mouse liver and intracellular fate of plasmid DNA after a rapid tail vein injection of a small or a large volume

1 reference

https://pubmed.ncbi.nlm.nih.gov/23735574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversibility of disulfide formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23735574

12 December 2020

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inferred from PubMed ID database lookup

Peptide-mediated gene delivery: influence of peptide structure on gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23735574

12 December 2020

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inferred from PubMed ID database lookup

Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iodinated plasmid DNA as a tool for studying gene delivery

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Albumin and Polyanion on the Structure of DNA Complexes with Polycation Containing Hydrophilic Nonionic Block

1 reference

https://pubmed.ncbi.nlm.nih.gov/23735574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JCONREL.2013.05.024

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Europe PubMed Central

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2 March 2020

PMC publication ID

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Europe PubMed Central

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2 March 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23735574%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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