Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways (Q41894661)

13 October 2017

Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways (English)

1 reference

13 October 2017

Dylan J Dues

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1 reference

13 October 2017

Emily K Andrews

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1 reference

13 October 2017

Claire E Schaar

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1 reference

13 October 2017

Alexis L Bergsma

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1 reference

13 October 2017

Megan M Senchuk

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13 October 2017

Jeremy M Van Raamsdonk

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1 reference

13 October 2017

5 April 2016

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13 October 2017

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13 October 2017

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13 October 2017

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13 October 2017

777-795

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describes a project that uses

13 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4925828/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Longevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegans

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5 June 2018

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5 June 2018

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5 June 2018

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Myricetin-mediated lifespan extension in Caenorhabditis elegans is modulated by DAF-16

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Caenorhabditis elegans HSF-1 is an essential nuclear protein that forms stress granule-like structures following heat shock

5 June 2018

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ROS in aging Caenorhabditis elegans: damage or signaling?

5 June 2018

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Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?

5 June 2018

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Superoxide dismutase is dispensable for normal animal lifespan

5 June 2018

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Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans

5 June 2018

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The unfolded protein response: from stress pathway to homeostatic regulation

5 June 2018

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FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1.

5 June 2018

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Taking a "good" look at free radicals in the aging process

5 June 2018

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A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans

5 June 2018

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Extending life span by increasing oxidative stress

5 June 2018

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Hypertonic stress induces rapid and widespread protein damage in C. elegans

5 June 2018

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Variable pathogenicity determines individual lifespan in Caenorhabditis elegans

5 June 2018

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A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans

5 June 2018

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5 June 2018

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Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity

5 June 2018

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The mitochondrial UPR - protecting organelle protein homeostasis

5 June 2018

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Insulin-like signaling determines survival during stress via posttranscriptional mechanisms in C. elegans

5 June 2018

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RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition.

5 June 2018

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Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?

5 June 2018

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Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity

5 June 2018

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Decreased energy metabolism extends life span in Caenorhabditis elegans without reducing oxidative damage

5 June 2018

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Hypoxia signaling and resistance in C. elegans

5 June 2018

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Growth and aging: a common molecular mechanism

5 June 2018

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Signalling pathways in the unfolded protein response: development from yeast to mammals

5 June 2018

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Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1.

5 June 2018

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Multiple mild heat-shocks decrease the Gompertz component of mortality in Caenorhabditis elegans

5 June 2018

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Is the oxidative stress theory of aging dead?

5 June 2018

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Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone

5 June 2018

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Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis

5 June 2018

1 reference

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Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans

5 June 2018

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Cell stress and aging: new emphasis on multiplex resistance mechanisms

5 June 2018

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Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

5 June 2018

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5 June 2018

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Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans

5 June 2018

1 reference

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Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

5 June 2018

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5 June 2018

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Hypoxic preconditioning requires the apoptosis protein CED-4 in C. elegans

5 June 2018

1 reference

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An explicit test of the phospholipid saturation hypothesis of acquired cold tolerance in Caenorhabditis elegans

5 June 2018

1 reference

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Hormesis and aging in Caenorhabditis elegans

5 June 2018

1 reference

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Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition

5 June 2018

1 reference

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The Caenorhabditis elegans rhy-1 gene inhibits HIF-1 hypoxia-inducible factor activity in a negative feedback loop that does not include vhl-1.

5 June 2018

1 reference

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Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity

5 June 2018

1 reference

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A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans

5 June 2018

1 reference

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Functional interaction between beta-catenin and FOXO in oxidative stress signaling

5 June 2018

1 reference

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The L-type cyclin CYL-1 and the heat-shock-factor HSF-1 are required for heat-shock-induced protein expression in Caenorhabditis elegans

5 June 2018

1 reference

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Aging: a theory based on free radical and radiation chemistry

5 June 2018

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SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

5 June 2018

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Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

5 June 2018

1 reference

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Stress resistance as a determinate of C. elegans lifespan

5 June 2018

1 reference

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Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity

5 June 2018

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

5 June 2018

1 reference

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daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

5 June 2018

1 reference

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Ageing and survival after different doses of heat shock: the results of analysis of data from stress experiments with the nematode worm Caenorhabditis elegans

5 June 2018

1 reference

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Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

5 June 2018

1 reference

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Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors

5 June 2018

1 reference

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Direct observation of stress response in Caenorhabditis elegans using a reporter transgene

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans.

5 June 2018

1 reference

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Stress-induced activation of the heat-shock response: cell and molecular biology of heat-shock factors.

5 June 2018

1 reference

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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

5 June 2018

1 reference

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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

5 June 2018

1 reference

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A C. elegans mutant that lives twice as long as wild type

5 June 2018

1 reference

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Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress

5 June 2018

1 reference

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Caenorhabditis elegans OSM-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Differential regulation of the heat shock factor 1 and DAF-16 by neuronal nhl-1 in the nematode C. elegans.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Selenite protects Caenorhabditis elegans from oxidative stress via DAF-16 and TRXR-1.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF-1 signaling pathways in C. elegans

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Tyrosol, a main phenol present in extra virgin olive oil, increases lifespan and stress resistance in Caenorhabditis elegans.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

C. elegans STI-1, the homolog of Sti1/Hop, is involved in aging and stress response

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Lifespan extension in Caenorhabditis elegans by complete removal of food.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Transcriptional targets of DAF-16 insulin signaling pathway protect C. elegans from extreme hypertonic stress

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

18 August 2018

1 reference

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Adaptation of the nematode Caenorhabditis elegans to extreme osmotic stress

18 August 2018

1 reference

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Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan

18 August 2018

1 reference

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Big mice die young: early life body weight predicts longevity in genetically heterogeneous mice.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Adaptive responses to oxidative damage in three mutants of Caenorhabditis elegans (age-1, mev-1 and daf-16) that affect life span

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925828

Lifespan extension of Caenorhabditis elegans following repeated mild hormetic heat treatments

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27053445

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reporter transgenes for study of oxidant stress in Caenorhabditis elegans

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27053445

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/AGING.100939

1 reference

13 October 2017

1 reference

13 October 2017

1 reference