Neural stem cells genetically modified to overexpress cu/zn-superoxide dismutase enhance amelioration of ischemic stroke in mice. (Q41884863)

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5 February 2020

title

Neural stem cells genetically modified to overexpress cu/zn-superoxide dismutase enhance amelioration of ischemic stroke in mice (English)

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5 February 2020

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2

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5 February 2020

author name string

Hiroyuki Sakata

1

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5 February 2020

Takuma Wakai

3

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5 February 2020

Purnima Narasimhan

4

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5 February 2020

Carolina M Maier

5

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5 February 2020

Pak H Chan

6

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5 February 2020

language of work or name

English

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publication date

19 June 2012

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5 February 2020

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5 February 2020

volume

43

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5 February 2020

issue

9

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5 February 2020

page(s)

2423-2429

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Stem cell research in stroke: how far from the clinic?

5 February 2020

cites work

1 reference

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Transplanted stem cell-secreted vascular endothelial growth factor effects poststroke recovery, inflammation, and vascular repair.

5 June 2018

1 reference

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Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner

5 June 2018

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Oxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotection

5 June 2018

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Stem cells in human neurodegenerative disorders--time for clinical translation?

5 June 2018

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CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia

5 June 2018

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FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis

5 June 2018

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FoxO3 regulates neural stem cell homeostasis

5 June 2018

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Optimizing the success of cell transplantation therapy for stroke

5 June 2018

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Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

5 June 2018

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Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.

5 June 2018

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A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death

5 June 2018

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Increased "vigilance" of antioxidant mechanisms in neural stem cells potentiates their capability to resist oxidative stress

5 June 2018

1 reference

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PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

5 June 2018

1 reference

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Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia

5 June 2018

1 reference

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Cell-density-dependent regulation of neural precursor cell function.

5 June 2018

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Reactive oxygen radicals in signaling and damage in the ischemic brain

5 June 2018

1 reference

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The use of transgenic and mutant mice to study oxygen free radical metabolism

5 June 2018

1 reference

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Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency

5 June 2018

1 reference

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Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion.

5 June 2018

1 reference

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Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia

5 June 2018

1 reference

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Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

5 June 2018

1 reference

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Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase

5 June 2018

1 reference

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Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II.

5 June 2018

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Consequences of ionizing radiation-induced damage in human neural stem cells

18 August 2018

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Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway.

18 August 2018

1 reference

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Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation.

18 August 2018

1 reference

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Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

18 August 2018

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Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency.

18 August 2018

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Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia

18 August 2018

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In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22713489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral infarction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22713489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1161/STROKEAHA.112.656900

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22713489%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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5 February 2020

PubMed publication ID

22713489

1 reference