The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage. (Q41858270)

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scientific article published on 17 September 2012

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English	The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage.	scientific article published on 17 September 2012

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scholarly article

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13 February 2020

The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage (English)

1 reference

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13 February 2020

Philip J. Coates

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13 February 2020

6

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13 February 2020

author name string

S M Nicol

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13 February 2020

S E Bray

2

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13 February 2020

H Derek Black

3

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13 February 2020

S A Lorimore

4

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13 February 2020

E G Wright

5

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13 February 2020

D W Meek

7

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13 February 2020

F V Fuller-Pace

9

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13 February 2020

language of work or name

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publication date

17 September 2012

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13 February 2020

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13 February 2020

32

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13 February 2020

3461-3469

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13 February 2020

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13 February 2020

https://scigraph.springernature.com/pub.10.1038/onc.2012.426

0 references

RNA helicases p68 and p72: multifunctional proteins with important implications for cancer development

1 reference

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5 June 2018

Regulation of the p53 transcriptional response by structurally diverse core promoters

1 reference

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5 June 2018

The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

Blinded by the Light: The Growing Complexity of p53

1 reference

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5 June 2018

The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

A complex barcode underlies the heterogeneous response of p53 to stress

1 reference

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5 June 2018

Mechanisms of regulatory diversity within the p53 transcriptional network

1 reference

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5 June 2018

Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation

1 reference

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5 June 2018

Living with p53, dying of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

Dead-box proteins: a family affair--active and passive players in RNP-remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

Phosphorylations of DEAD box p68 RNA helicase are associated with cancer development and cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

1 reference

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5 June 2018

Tissue-specific induction of p53 targets in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

GADD45 induction of a G2/M cell cycle checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

5 June 2018

The p53 response to ionising radiation in adult and developing murine tissues.

1 reference

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5 June 2018

Discordance between accumulated p53 protein level and its transcriptional activity in response to u.v. radiation.

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5 June 2018

Tissue-specific p53 responses to ionizing radiation and their genetic modification: the key to tissue-specific tumour susceptibility?

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18 August 2018

The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21(CIP1/Waf1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3556166

18 August 2018

Overexpression and poly-ubiquitylation of the DEAD-box RNA helicase p68 in colorectal tumours.

1 reference

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18 August 2018

Differential post-translational modification of the tumour suppressor proteins Rb and p53 modulate the rates of radiation-induced apoptosis in vivo

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https://api.crossref.org/works/10.1038%2FONC.2012.426

31 March 2020

Synergistic interactions allow colony formation in vitro by murine haemopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.426

31 March 2020

A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.426

31 March 2020

Bromodeoxyuridine/DNA analysis of replication in CHO cells after exposure to UV light

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https://api.crossref.org/works/10.1038%2FONC.2012.426

31 March 2020

The effect of p53 status on the radiosensitivity of haemopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22986526

12 December 2020

based on heuristic

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Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22986526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/22986526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/ONC.2012.426

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13 February 2020

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1 reference

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13 February 2020

1 reference

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13 February 2020

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