Drugs and trafficking of ion channels: a new pro-arrhythmic threat on the horizon? (Q41856022)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18059314%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Drugs and trafficking of ion channels: a new pro-arrhythmic threat on the horizon? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18059314%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author

Marcel van der Heyden

series ordinal

1

1 reference

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29 December 2019

author name string

Smits ME

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18059314%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Vos MA

series ordinal

3

1 reference

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29 December 2019

language of work or name

English

0 references

publication date

3 December 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18059314%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

29 December 2019

published in

1 reference

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29 December 2019

volume

153

1 reference

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29 December 2019

issue

3

1 reference

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29 December 2019

page(s)

406-409

1 reference

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Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome

29 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Co-chaperone FKBP38 promotes HERG trafficking

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Mechanisms of cardiac potassium channel trafficking

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Combined hERG channel inhibition and disruption of trafficking in drug-induced long QT syndrome by fluoxetine: a case-study in cardiac safety pharmacology.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Assessing the proarrhythmic potential of drugs: current status of models and surrogate parameters of torsades de pointes arrhythmias.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Chronic inhibition of cardiac Kir2.1 and HERG potassium channels by celastrol with dual effects on both ion conductivity and protein trafficking.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Drug-induced torsades de pointes: the evolving role of pharmacogenetics

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

HERG-Lite: a novel comprehensive high-throughput screen for drug-induced hERG risk

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Pentamidine reduces hERG expression to prolong the QT interval

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Protein trafficking abnormalities: a new mechanism in drug-induced long QT syndrome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Blockade of HERG and Kv1.5 by ketoconazole

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Incidence of cardiac arrhythmias during intravenous pentamidine therapy in HIV-infected patients

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

The effect of flunarizine and ryanodine on acquired torsades de pointes arrhythmias in the intact canine heart

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Delayed cardiotoxicity during treatment with intravenous pentamidine: two case reports and a review of the literature

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Drug block of the hERG potassium channel: insight from modeling.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Ketoconazole induced torsades de pointes without concomitant use of QT interval-prolonging drug

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Pentamidine-induced long QT syndrome and block of hERG trafficking

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Mechanisms of arsenic-induced prolongation of cardiac repolarization

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Unusual effects of a QT-prolonging drug, arsenic trioxide, on cardiac potassium currents

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

A prospective study of the effect of I.V. pentamidine therapy on ventricular arrhythmias and QTc prolongation in HIV-infected patients

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2241779

Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18059314

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18059314

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.BJP.0707618

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18059314%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18059314%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference