Evolutionary Analysis of Sequence Divergence and Diversity of Duplicate Genes in Aspergillus fumigatus. (Q41855959)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Evolutionary Analysis of Sequence Divergence and Diversity of Duplicate Genes in Aspergillus fumigatus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

Putative alpha-1,3-glucanase

20 February 2020

main subject

Aspergillus fumigatus

0 references

1 reference

5 February 2019

1 reference

Transcript up-regulated in conidia exposed to neutrophils

5 February 2019

1 reference

Putative c-14 sterol reductase with a predicted role in ergosterol biosynthesis

5 February 2019

1 reference

Putative c-14 sterol reductase with a predicted role in ergosterol biosynthesis

5 February 2019

1 reference

Putative P-type calcium ATPase

5 February 2019

1 reference

Ortholog(s) have role in galactitol catabolic process, galactose catabolic process

5 February 2019

1 reference

Has domain(s) with predicted RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity, role in regulation of transcription, DNA-templated and nucleus localization

5 February 2019

1 reference

5 February 2019

1 reference

Putative Arsenic resistance protein

5 February 2019

1 reference

Ortholog of A. nidulans FGSC A4 : AN3975, AN9193/llmJ, AN2891 and A. fumigatus Af293 : Afu1g10150, Afu3g15150, Afu3g15280, Afu6g03300

5 February 2019

1 reference

5 February 2019

C6 finger domain protein

1 reference

Has domain(s) with predicted role in response to stress and integral component of membrane localization

5 February 2019

1 reference

Ortholog(s) have cytosol, nucleus localization

5 February 2019

1 reference

putative glycosyl hydrolase

5 February 2019

1 reference

5 February 2019

ThiJ/PfpI family protein

1 reference

6 February 2019

Putative protein kinase

1 reference

Has domain(s) with predicted ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding activity

6 February 2019

1 reference

Putative calcium-translocating P-type ATPase involved in depleting the cytosol of calcium ions

6 February 2019

1 reference

methyltransferase, putative

6 February 2019

1 reference

6 February 2019

Dehydrin-like protein

1 reference

6 February 2019

ThiJ/PfpI family protein

1 reference

Putative GPI anchored glycosyl hydrolase

6 February 2019

1 reference

Ortholog of A. nidulans FGSC A4 : AN3193, A. oryzae RIB40 : AO090001000177, Aspergillus wentii : Aspwe1_0115469, Aspergillus sydowii : Aspsy1_0414254 and Aspergillus terreus NIH2624 : ATET_07904

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

Ortholog(s) have mRNA binding activity and role in chromatin silencing at centromere outer repeat region, mRNA splicing, via spliceosome, negative regulation of G0 to G1 transition

1 reference

Ortholog of A. nidulans FGSC A4 : AN3546, A. fumigatus Af293 : Afu1g16170, Afu5g15040, Afu6g09300, A. niger CBS 513.88 : An08g11160, An04g08000 and A. oryzae RIB40 : AO090166000001

6 February 2019

1 reference

Putative DEAD/DEAH box helicase

6 February 2019

1 reference

Ortholog(s) have Golgi apparatus localization

6 February 2019

1 reference

6 February 2019

1 reference

Ortholog(s) have carbonyl reductase (NADPH) activity, serine 3-dehydrogenase activity and cytosol, nucleus, ribosome localization

6 February 2019

1 reference

Has domain(s) with predicted RNA polymerase II transcription factor activity, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding, zinc ion binding activity

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

Has domain(s) with predicted ATP binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups activity and role in protein phosphorylation

6 February 2019

1 reference

EmrB/QacA family ABC multidrug transporter

6 February 2019

1 reference

Ortholog(s) have L-asparagine transmembrane transporter activity, L-isoleucine transmembrane transporter activity, L-lysine transmembrane transporter activity

6 February 2019

1 reference

Has domain(s) with predicted oxidoreductase activity and role in metabolic process

6 February 2019

1 reference

Has domain(s) with predicted DNA binding activity and role in DNA integration, DNA recombination

6 February 2019

1 reference

Ortholog of Aspergillus fumigatus A1163 : AFUB_092640

6 February 2019

1 reference

Has domain(s) with predicted ATP binding, ligase activity, tetrahydrofolylpolyglutamate synthase activity and role in biosynthetic process, folic acid-containing compound biosynthetic process

6 February 2019

1 reference

Has domain(s) with predicted role in response to stress and integral component of membrane localization

6 February 2019

1 reference

Fungal dehydrin-like protein that plays a role in oxidative, osmotic and pH stress responses

6 February 2019

1 reference

Ortholog of A. nidulans FGSC A4 : AN0196, A. fumigatus Af293 : Afu5g14200, Afu6g13810, Afu8g01720, A. niger CBS 513.88 : An13g02610, An15g02090, An04g09640 and A. oryzae RIB40 : AO090003001444

6 February 2019

1 reference

Transcript up-regulated in conidia exposed to neutrophils

6 February 2019

1 reference

Putative alpha-1,3-glucanase

6 February 2019

1 reference

Has domain(s) with predicted ATP binding, ligase activity, tetrahydrofolylpolyglutamate synthase activity and role in biosynthetic process, folic acid-containing compound biosynthetic process

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Amanda M. Hulse-Kemp

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

James J. Cai

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

Amanda M Hulse

series ordinal

2

1 reference

13 October 2017

19 November 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

Evolutionary Bioinformatics

20 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

page(s)

623-644

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

Gene duplication as a mechanism of genomic adaptation to a changing environment

20 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Global transcriptome changes underlying colony growth in the opportunistic human pathogen Aspergillus fumigatus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Genomic evidence of repeat-induced point mutation (RIP) in filamentous ascomycetes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Enemy of the (immunosuppressed) state: an update on the pathogenesis of Aspergillus fumigatus infection.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Distinguishing among evolutionary models for the maintenance of gene duplicates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

MBEToolbox 2.0: an enhanced version of a MATLAB toolbox for molecular biology and evolution

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Adaptive evolution of young gene duplicates in mammals.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

The population genetics of dN/dS

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Discovery of a sexual cycle in the opportunistic fungal pathogen Aspergillus fumigatus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

"Reverse ecology" and the power of population genomics

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Aspergillus fumigatus: principles of pathogenesis and host defense

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Natural history and evolutionary principles of gene duplication in fungi.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Reconstructing the early evolution of Fungi using a six-gene phylogeny

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Natural selection on protein-coding genes in the human genome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Reproduction in Aspergillus fumigatus: sexuality in a supposedly asexual species?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

An ergot alkaloid biosynthesis gene and clustered hypothetical genes from Aspergillus fumigatus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Genome evolution in yeasts

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Widespread paleopolyploidy in model plant species inferred from age distributions of duplicate genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Asymmetric sequence divergence of duplicate genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Different evolutionary patterns between young duplicate genes in the human genome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

The evolutionary demography of duplicate genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

The genome sequence of the filamentous fungus Neurospora crassa

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Selection on rapidly evolving proteins in the Arabidopsis genome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Selection in the evolution of gene duplications

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

The genome sequence of Schizosaccharomyces pombe

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

A general empirical model of protein evolution derived from multiple protein families using a maximum-likelihood approach

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Gene duplication and the structure of eukaryotic genomes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Statistical methods for detecting molecular adaptation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

The evolutionary fate and consequences of duplicate genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Genome organization in dicots: genome duplication in Arabidopsis and synteny between soybean and Arabidopsis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Comparative genomics of the eukaryotes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Evolutionary preservation of redundant duplicated genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Aspergillus fumigatus and aspergillosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Preservation of duplicate genes by complementary, degenerative mutations

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Extent of genomic rearrangement after genome duplication in yeast

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

PAML: a program package for phylogenetic analysis by maximum likelihood

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Expressed sequences from conidial, mycelial, and sexual stages of Neurospora crassa.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Molecular evidence for an ancient duplication of the entire yeast genome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Gen(om)e duplications in the evolution of early vertebrates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Dimorphism and haploid fruiting in Cryptococcus neoformans: association with the alpha-mating type

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

A codon-based model of nucleotide substitution for protein-coding DNA sequences

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

A likelihood approach for comparing synonymous and nonsynonymous nucleotide substitution rates, with application to the chloroplast genome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Population genetics of polymorphism and divergence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

The McDonald-Kreitman test and slightly deleterious mutations.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Evidence for sexuality in the opportunistic fungal pathogen Aspergillus fumigatus.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

A maximum likelihood method for detecting functional divergence at individual codon sites, with application to gene family evolution

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Patterns of nucleotide substitution among simultaneously duplicated gene pairs in Arabidopsis thaliana

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

The cost of inbreeding in Arabidopsis.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Extent of gene duplication in the genomes of Drosophila, nematode, and yeast.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

The ghost of selection past: rates of evolution and functional divergence of anciently duplicated genes.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Evolutionary rates of duplicate genes in fish and mammals.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Differential selection after duplication in mammalian developmental genes.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510868

Evolution of duplicate genes in a tetraploid animal, Xenopus laevis

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23225993

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of virulence factors and diagnostic markers using immunosecretome of Aspergillus fumigatus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23225993

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4137/EBO.S10372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23225993%20AND%20SRC:MED&resulttype=core&format=json