Targeting SRC and epidermal growth factor receptor in colorectal cancer: rationale and progress into the clinic. (Q41846085)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Targeting SRC and epidermal growth factor receptor in colorectal cancer: rationale and progress into the clinic (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

Scott Kopetz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

publication date

1 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json

Gastrointestinal cancer research : GCR

25 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

4 Suppl 2

1 reference

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25 January 2020

page(s)

S37-41

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json

Clinical development of SRC tyrosine kinase inhibitors in lung cancer

25 January 2020

cites work

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Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression

6 June 2018

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6 June 2018

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Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model

6 June 2018

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c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK.

6 June 2018

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Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis

6 June 2018

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Epidermal growth factor receptor (EGFR)-related protein inhibits multiple members of the EGFR family in colon and breast cancer cells

6 June 2018

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Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor

6 June 2018

1 reference

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Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis

6 June 2018

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

6 June 2018

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SRC gene expression in human cancer: the role of transcriptional activation

6 June 2018

1 reference

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Src family kinases in tumor progression and metastasis

6 June 2018

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Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors

6 June 2018

1 reference

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STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor

6 June 2018

1 reference

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Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor

6 June 2018

1 reference

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Activation of Src kinase in primary colorectal carcinoma: an indicator of poor clinical prognosis

6 June 2018

1 reference

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PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells

6 June 2018

1 reference

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pp60(cSrc) is a caspase-3 substrate and Is essential for the transformed phenotype of A431 cells

6 June 2018

1 reference

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Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways

6 June 2018

1 reference

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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842

Stat3 activation is required for cellular transformation by v-src

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842

c-Src is required for stimulation of gelsolin-associated phosphatidylinositol 3-kinase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842

Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666842

A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer

6 June 2018

1 reference

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

6 June 2018

1 reference

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The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

6 June 2018

1 reference

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Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

6 June 2018

1 reference

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DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

6 June 2018

1 reference

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Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

6 June 2018

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Epidermal‐Growth‐Factor‐Dependent Activation of the Src‐Family Kinases

6 June 2018

1 reference

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pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src

6 June 2018

1 reference

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Activation of pp60c-src protein kinase activity in human colon carcinoma

6 June 2018

1 reference

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Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells

6 June 2018

1 reference

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Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

18 August 2018

1 reference

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Somatic mutations of EGFR in colorectal cancers and glioblastomas

18 August 2018

1 reference

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Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19360146

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Site-specific differences in pp60c-src activity in human colorectal metastases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19360146

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19360146%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

19360146

1 reference