Substrate recognition by β-ketoacyl-ACP synthases. (Q41844519)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017312%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Substrate recognition by β-ketoacyl-ACP synthases (English)

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15 January 2020

2

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15 January 2020

Peter J. Tonge

5

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15 January 2020

author name string

Janine G Borgaro

1

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15 January 2020

Carl A Machutta

3

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15 January 2020

Xujie Zhang

4

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15 January 2020

language of work or name

English

0 references

publication date

17 November 2011

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15 January 2020

number of pages

9

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based on heuristic

inferred from page(s)

published in

Biochemistry

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15 January 2020

volume

50

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15 January 2020

page(s)

10678-10686

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15 January 2020

issue

49

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017312%20AND%20SRC:MED&resulttype=core&format=json

Expression of Vibrio harveyi acyl-ACP synthetase allows efficient entry of exogenous fatty acids into the Escherichia coli fatty acid and lipid A synthetic pathways

15 January 2020

cites work

1 reference

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Slow onset inhibition of bacterial beta-ketoacyl-acyl carrier protein synthases by thiolactomycin

6 June 2018

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An eight residue fragment of an acyl carrier protein suffices for post-translational introduction of fluorescent pantetheinyl arms in protein modification in vitro and in vivo

6 June 2018

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Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching

6 June 2018

1 reference

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Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes

6 June 2018

1 reference

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Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases

6 June 2018

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Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

6 June 2018

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Synthesis and biological evaluation of thiazolidine-2-one 1,1-dioxide as inhibitors of Escherichia coli beta-ketoacyl-ACP-synthase III (FabH).

6 June 2018

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Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli

6 June 2018

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Platensimycin is a selective FabF inhibitor with potent antibiotic properties

6 June 2018

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Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis.

6 June 2018

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Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A

6 June 2018

1 reference

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The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance

6 June 2018

1 reference

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β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) Is Essential for Bacterial Fatty Acid Synthesis

6 June 2018

1 reference

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Structural and functional organization of the animal fatty acid synthase

6 June 2018

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Genes required for mycobacterial growth defined by high density mutagenesis

6 June 2018

1 reference

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The role of KasA and KasB in the biosynthesis of meromycolic acids and isoniazid resistance in Mycobacterium tuberculosis

6 June 2018

1 reference

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Mechanistic diversity and regulation of Type II fatty acid synthesis

6 June 2018

1 reference

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MabA (FabG1), a Mycobacterium tuberculosis protein involved in the long-chain fatty acid elongation system FAS-II

6 June 2018

1 reference

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Exploiting genomics to discover new antibiotics

6 June 2018

1 reference

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Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB

6 June 2018

1 reference

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Bacterial fatty acid biosynthesis: targets for antibacterial drug discovery

6 June 2018

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Bacterial fatty-acid biosynthesis: a genomics-driven target for antibacterial drug discovery

6 June 2018

1 reference

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Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361727

Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism

6 June 2018

1 reference

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Identification and substrate specificity of beta -ketoacyl (acyl carrier protein) synthase III (mtFabH) from Mycobacterium tuberculosis

6 June 2018

1 reference

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beta-ketoacyl-acyl carrier protein synthase III (FabH) is a determining factor in branched-chain fatty acid biosynthesis

6 June 2018

1 reference

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Mycolic acids: structure, biosynthesis and physiological functions

6 June 2018

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Synergistic activities of antituberculous drugs with cerulenin and trans-cinnamic acid against Mycobacterium tuberculosis

6 June 2018

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Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

6 June 2018

1 reference

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Inhibition of beta-ketoacyl-acyl carrier protein synthase III (FabH) by acyl-acyl carrier protein in Escherichia coli.

6 June 2018

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inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

6 June 2018

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Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis

6 June 2018

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Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis

6 June 2018

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The Envelope of Mycobacteria

6 June 2018

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Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase

6 June 2018

1 reference

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Beta-ketoacyl-acyl carrier protein synthase II of Escherichia coli. Evidence for function in the thermal regulation of fatty acid synthesis

6 June 2018

1 reference

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Acyl carrier protein. XV. Studies of -ketoacyl-acyl carrier protein synthetase.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361727

The kinetics of coupled enzyme reactions. Applications to the assay of glucokinase, with glucose 6-phosphate dehydrogenase as coupling enzyme

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361727

Physical properties of fatty acyl-CoA. Critical micelle concentrations and micellar size and shape.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361727

Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors

6 June 2018

1 reference

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Expression, purification, crystallization and preliminary X-ray crystallographic analysis of pantothenate kinase from Mycobacterium tuberculosis

18 August 2018

1 reference

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Key residues responsible for acyl carrier protein and beta-ketoacyl-acyl carrier protein reductase (FabG) interaction

18 August 2018

1 reference

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Analogues of thiolactomycin: potential drugs with enhanced anti-mycobacterial activity

18 August 2018

1 reference

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Effects of sequential proline substitutions on amyloid formation by human amylin20-29.

18 August 2018

1 reference

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Cloning of the fabF gene in an expression vector and in vitro characterization of recombinant fabF and fabB encoded enzymes from Escherichia coli.

18 August 2018

1 reference

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Regulation of fatty acid elongation and initiation by acyl-acyl carrier protein in Escherichia coli.

18 August 2018

1 reference

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Thermal regulation of membrane fluidity in Escherichia coli. Effects of overproduction of beta-ketoacyl-acyl carrier protein synthase I

18 August 2018

1 reference

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Chemical and posttranslational modification of Escherichia coli acyl carrier protein for preparation of dansyl-acyl carrier proteins

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22017312

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI201199X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017312%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22017312%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference