Pyrrolinone-based peptidomimetics. "Let the enzyme or receptor be the judge". (Q41839799)

13 October 2017

Pyrrolinone-based peptidomimetics. "Let the enzyme or receptor be the judge". (English)

1 reference

13 October 2017

Amos B Smith

1

1 reference

13 October 2017

Adam K Charnley

series ordinal

2

1 reference

13 October 2017

Ralph Hirschmann

series ordinal

3

1 reference

13 October 2017

22 December 2010

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Accounts of Chemical Research

13 October 2017

1 reference

13 October 2017

44

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13 October 2017

3

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13 October 2017

180-193

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Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 2. Macrocyclic hexapyrrolinones

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 1. From nonpeptide peptidomimetics to nanotubes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

The beta-D-glucose scaffold as a beta-turn mimetic

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Peptide mimics by linear arylamides: a structural and functional diversity test

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Proteases universally recognize beta strands in their active sites

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

HIV-1 protease: mechanism and drug discovery

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

The renin-angiotensin-aldosterone system: cardiorenal effects and implications for renal and cardiovascular disease states

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Design, Synthesis, and Biological Evaluation of Monopyrrolinone-Based HIV-1 Protease Inhibitors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Synthesis of polypyrrolinones on solid support

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

An orally bioavailable pyrrolinone inhibitor of HIV-1 protease: computational analysis and X-ray crystal structure of the enzyme complex

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

High-affinity binding of short peptides to major histocompatibility complex class II molecules by anchor combinations

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Collagenase inhibitors: their design and potential therapeutic use.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

L-687,908, a potent hydroxyethylene-containing HIV protease inhibitor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl substituents: X-ray crystal structure assisted design

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Conformationally restricted bicyclic analogs of somatostatin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Self-assembly of noncyclic bis-D- and L-tripeptides into higher order tubular constructs: design, synthesis, and X-ray crystal superstructure

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078624

A second-generation synthesis of polypyrrolinone nonpeptidomimetics: prelude to the synthesis of polypyrrolinones on solid support

18 August 2018

1 reference

12 December 2020

Design, synthesis, and evaluation of a pyrrolinone-based matrix metalloprotease inhibitor

1 reference

12 December 2020

Somatostatin analogs which define the role of the lysine-9 amino group

1 reference

12 December 2020

New human renin inhibitors containing an unnatural amino acid, norstatine

1 reference

12 December 2020

A Molecular Basis for MHC Class II—Associated Autoimmunity

1 reference

12 December 2020

Renin inhibitors. Dipeptide analogues of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency

1 reference

12 December 2020

Design and synthesis of peptidomimetic inhibitors of HIV-1 protease and renin. Evidence for improved transport

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12 December 2020

The design and synthesis of 2,5-linked pyrrolinones. A potential non-peptide peptidomimetic scaffold

1 reference

12 December 2020

Molecular modeling, synthesis, and structures of N-methylated 3,5-linked pyrrolin-4-ones toward the creation of a privileged nonpeptide scaffold

1 reference

12 December 2020

Design, synthesis, and binding affinities of pyrrolinone-based somatostatin mimetics

1 reference

12 December 2020

Matrix metalloproteinases

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12 December 2020

Identifiers

DOI

10.1021/AR1001186

1 reference

13 October 2017

1 reference

13 October 2017

PubMed publication ID

21175156

1 reference