Regulatory decisions pertaining to aprotinin may be putting patients at risk (Q41823314)

12 October 2017

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title

Regulatory decisions pertaining to aprotinin may be putting patients at risk (English)

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12 October 2017

8

George Wells

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12 October 2017

10

Jean Bussières

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12 October 2017

Paul C Hébert

1

1 reference

12 October 2017

Dean A Fergusson

2

1 reference

12 October 2017

Brian Hutton

3

1 reference

12 October 2017

C David Mazer

4

1 reference

12 October 2017

Stephen Fremes

5

1 reference

12 October 2017

Morris Blajchman

6

1 reference

12 October 2017

Charles MacAdams

7

1 reference

12 October 2017

Jim Robblee

9

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12 October 2017

Kevin Teoh

11

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12 October 2017

BART Investigators

12

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12 October 2017

language of work or name

English

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publication date

29 September 2014

1 reference

Canadian Medical Association Journal

12 October 2017

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12 October 2017

186

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12 October 2017

18

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12 October 2017

1379-1386

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Risks of harms using antifibrinolytics in cardiac surgery: systematic review and network meta-analysis of randomised and observational studies

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Aprotinin increases mortality as compared with tranexamic acid in cardiac surgery: a meta-analysis of randomized head-to-head trials

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

A comparison of aprotinin and lysine analogues in high-risk cardiac surgery

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

The effect of aprotinin on outcome after coronary-artery bypass grafting

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Aprotinin during coronary-artery bypass grafting and risk of death

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

The risk associated with aprotinin in cardiac surgery

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Randomized controlled trials of aprotinin in cardiac surgery: could clinical equipoise have stopped the bleeding?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Are antifibrinolytic drugs equivalent in reducing blood loss and transfusion in cardiac surgery? A meta-analysis of randomized head-to-head trials

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery: a systematic review and meta-analysis of randomized clinical trials

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Post-randomisation exclusions: the intention to treat principle and excluding patients from analysis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Metaanalysis of prophylactic drug treatment in the prevention of postoperative bleeding.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Mortality manifesto: a meta-analysis of aprotinin and tranexamic acid mortality.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Evaluation of a novel kallikrein inhibitor on hemostatic activation in vitro.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259771

Are tranexamic acid and ε-aminocaproic acid adequate substitutes for aprotinin?

18 August 2018

1 reference

12 December 2020

Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints

1 reference

12 December 2020

Aprotinin prolongs activated and nonactivated whole blood clotting time and potentiates the effect of heparin in vitro

1 reference

12 December 2020

Drugs to minimize perioperative blood loss in cardiac surgery: meta-analyses using perioperative blood transfusion as the outcome. The International Study of Peri-operative Transfusion (ISPOT) Investigators

1 reference

12 December 2020

Identifiers

DOI

10.1503/CMAJ.131582

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12 October 2017

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12 October 2017

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