Protease inhibitors derived from elafin and SLPI and engineered to have enhanced specificity towards neutrophil serine proteases. (Q41818079)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19241385%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Protease inhibitors derived from elafin and SLPI and engineered to have enhanced specificity towards neutrophil serine proteases (English)

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22 January 2020

author

Sandrine Dallet-Choisy

4

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22 January 2020

author name string

Marie-Louise Zani

1

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22 January 2020

Kévin Baranger

2

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22 January 2020

Nicolas Guyot

3

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22 January 2020

Thierry Moreau

5

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22 January 2020

publication date

1 March 2009

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22 January 2020

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22 January 2020

volume

18

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22 January 2020

issue

3

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22 January 2020

page(s)

579-594

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Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease

22 January 2020

cites work

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Inhibition of human neutrophil elastase-induced acute lung injury in hamsters by recombinant human pre-elafin (trappin-2).

6 June 2018

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Structure-function relationship of serine protease-protein inhibitor interaction.

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor

6 June 2018

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6 June 2018

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The antibacterial and antifungal properties of trappin-2 (pre-elafin) do not depend on its protease inhibitory function.

6 June 2018

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Characterization of human pre-elafin mutants: full antipeptidase activity is essential to preserve lung tissue integrity in experimental emphysema

18 August 2018

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18 August 2018

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Elafin and its precursor trappin-2 still inhibit neutrophil serine proteinases when they are covalently bound to extracellular matrix proteins by tissue transglutaminase

18 August 2018

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Oxidized elafin and trappin poorly inhibit the elastolytic activity of neutrophil elastase and proteinase 3.

18 August 2018

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18 August 2018

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18 August 2018

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18 August 2018

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18 August 2018

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18 August 2018

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18 August 2018

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18 August 2018

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Anti-Inflammatory Effect of Pre-Elafin in Lipopolysaccharide-Induced Acute Lung Inflammation

2 December 2018

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Regulation of proteolysis at the neutrophil-substrate interface by secretory leukoprotease inhibitor

2 December 2018

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12 December 2020

Bioactive proteinase 3 on the cell surface of human neutrophils: quantification, catalytic activity, and susceptibility to inhibition

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12 December 2020

Separation of the two domains of human mucus proteinase inhibitor: inhibitory activity is only located in the carboxy-terminal domain

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12 December 2020

Elastase inhibitor elafin is a new type of proteinase inhibitor which has a transglutaminase-mediated anchoring sequence termed "cementoin"

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12 December 2020

5 Theoretical and practical aspects of proteinase inhibition kinetics

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12 December 2020

Homology modelling of rat kallikrein rK9, a member of the tissue kallikrein family: implications for substrate specificity and inhibitor binding

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12 December 2020

Secretory leukocyte proteinase inhibitor is a major leukocyte elastase inhibitor in human neutrophils

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12 December 2020

Increased local levels of granulocyte colony-stimulating factor are associated with the beneficial effect of pre-elafin (SKALP/trappin-2/WAP3) in experimental emphysema

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12 December 2020

Accumulation of elafin in actinic elastosis of sun-damaged skin: elafin binds to elastin and prevents elastolytic degradation

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12 December 2020

Proteinase inhibitory activities of antileukoprotease are represented by its second COOH-terminal domain

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12 December 2020

Identifiers

DOI

10.1002/PRO.64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19241385%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19241385%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

19241385

1 reference