Hepatocyte-specific Ptpn6 deletion protects from obesity-linked hepatic insulin resistance (Q41814839)

12 October 2017

Hepatocyte-specific Ptpn6 deletion protects from obesity-linked hepatic insulin resistance (English)

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12 October 2017

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Elaine Xu

1

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12 October 2017

Alexandre Charbonneau

2

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12 October 2017

Yannève Rolland

3

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12 October 2017

Kerstin Bellmann

4

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12 October 2017

Lily Pao

5

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12 October 2017

Katherine A Siminovitch

6

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12 October 2017

Benjamin G Neel

7

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12 October 2017

Nicole Beauchemin

8

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12 October 2017

André Marette

9

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12 October 2017

language of work or name

English

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publication date

14 June 2012

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12 October 2017

10

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inferred from page(s)

published in

Diabetes

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12 October 2017

61

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12 October 2017

8

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12 October 2017

1949-1958

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

12 October 2017

start time

30 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3402325/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Compartmentalized CDK2 is connected with SHP-1 and β-catenin and regulates insulin internalization

6 June 2018

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Prep1 controls insulin glucoregulatory function in liver by transcriptional targeting of SHP1 tyrosine phosphatase

6 June 2018

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Inducible nitric oxide synthase induction underlies lipid-induced hepatic insulin resistance in mice: potential role of tyrosine nitration of insulin signaling proteins

6 June 2018

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Decreased osteoclastogenesis and high bone mass in mice with impaired insulin clearance due to liver-specific inactivation to CEACAM1

6 June 2018

1 reference

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Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance

6 June 2018

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Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling

6 June 2018

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Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress

6 June 2018

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Development of nonalcoholic steatohepatitis in insulin-resistant liver-specific S503A carcinoembryonic antigen-related cell adhesion molecule 1 mutant mice

6 June 2018

1 reference

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Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism

6 June 2018

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Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance

6 June 2018

1 reference

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Insulin acutely decreases hepatic fatty acid synthase activity

6 June 2018

1 reference

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Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins: evidence from protein tyrosine phosphatase-1B overexpression, knockout, and RNAi studies

6 June 2018

1 reference

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PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance

6 June 2018

1 reference

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CEACAM1 regulates insulin clearance in liver

6 June 2018

1 reference

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

6 June 2018

1 reference

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Regulation of colony-stimulating factor 1 receptor signaling by the SH2 domain-containing tyrosine phosphatase SHPTP1

6 June 2018

1 reference

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Expression of dominant negative mutant SHPTP2 attenuates phosphatidylinositol 3'-kinase activity via modulation of phosphorylation of insulin receptor substrate-1.

6 June 2018

1 reference

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Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin.

6 June 2018

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Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation

6 June 2018

1 reference

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Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

6 June 2018

1 reference

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Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells. Phosphatidic acid activates receptor dephosphorylation by PTP1C

6 June 2018

1 reference

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Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

Adapter function of protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interaction

6 June 2018

1 reference

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Isolation of a src homology 2-containing tyrosine phosphatase

6 June 2018

1 reference

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Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13.

6 June 2018

1 reference

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A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences

6 June 2018

1 reference

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Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action

6 June 2018

1 reference

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Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

Kupffer cell activation is a causal factor for hepatic insulin resistance

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

Targeted disruption of carcinoembryonic antigen-related cell adhesion molecule 1 promotes diet-induced hepatic steatosis and insulin resistance.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

Beta-Cell hyperplasia induced by hepatic insulin resistance: role of a liver-pancreas endocrine axis through insulin receptor A isoform

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

Role of hepatic glycogen breakdown in defective counterregulation of hypoglycemia in intensively treated type 1 diabetes

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

Expression of a dominant negative SHP-2 in transgenic mice induces insulin resistance.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402325

Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney

18 August 2018

1 reference

12 December 2020

Interleukin-4 (IL-4) induces phosphatidylinositol 3-kinase (p85) dephosphorylation. Implications for the role of SHP-1 in the IL-4-induced signals in human B cells

1 reference

12 December 2020

SHP-1 associates with both platelet-derived growth factor receptor and the p85 subunit of phosphatidylinositol 3-kinase

1 reference

12 December 2020

SHP-1 regulates Lck-induced phosphatidylinositol 3-kinase phosphorylation and activity

1 reference

12 December 2020

The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis

1 reference

12 December 2020

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB11-1502

1 reference

release_ic4ai5lmyfctxmbcmoca6ktiv4

12 October 2017

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Fatcat

https://api.fatcat.wiki/v0/release/ic4ai5lmyfctxmbcmoca6ktiv4

24 November 2022

mapped directly with Wikidata item

1 reference

12 October 2017

1 reference