Allosteric Interactions between NMDA Receptor Subunits Shape the Developmental Shift in Channel Properties (Q41791764)

10 June 2018

title

Allosteric Interactions between NMDA Receptor Subunits Shape the Developmental Shift in Channel Properties (English)

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10 June 2018

author name string

Weinan Sun

series ordinal

1

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10 June 2018

Kasper B Hansen

series ordinal

2

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10 June 2018

Craig E Jahr

series ordinal

3

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10 June 2018

language of work or name

English

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publication date

1 April 2017

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10 June 2018

published in

Neuron

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10 June 2018

volume

94

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10 June 2018

issue

1

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10 June 2018

page(s)

58-64.e3

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10 June 2018

Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.

cites work

1 reference

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MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit

14 June 2018

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Controlling NMDA receptor subunit composition using ectopic retention signals

14 June 2018

1 reference

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Distinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors.

14 June 2018

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Triheteromeric NMDA receptors at hippocampal synapses

14 June 2018

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Structural Determinants of Agonist Efficacy at the Glutamate Binding Site of N-Methyl-D-Aspartate Receptors

14 June 2018

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Activated CaMKII couples GluN2B and casein kinase 2 to control synaptic NMDA receptors

14 June 2018

1 reference

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The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults

14 June 2018

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Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors

14 June 2018

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Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses

14 June 2018

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NMDA receptors with locked glutamate-binding clefts open with high efficacy.

14 June 2018

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Glutamate receptor ion channels: structure, regulation, and function

14 June 2018

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Novel approach to probe subunit-specific contributions to N-methyl-D-aspartate (NMDA) receptor trafficking reveals a dominant role for NR2B in receptor recycling

14 June 2018

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Distinct roles of NR2A and NR2B cytoplasmic tails in long-term potentiation

14 June 2018

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Control of NMDA receptor function by the NR2 subunit amino-terminal domain

14 June 2018

1 reference

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Mechanism of differential control of NMDA receptor activity by NR2 subunits

14 June 2018

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Constitutive activation of the N-methyl-D-aspartate receptor via cleft-spanning disulfide bonds

14 June 2018

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NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

14 June 2018

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NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII.

14 June 2018

1 reference

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Developmental regulation of cognitive abilities: modified composition of a molecular switch turns on associative learning

14 June 2018

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Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles.

14 June 2018

1 reference

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The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

14 June 2018

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Enhanced NR2A subunit expression and decreased NMDA receptor decay time at the onset of ocular dominance plasticity in the ferret

14 June 2018

1 reference

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Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

14 June 2018

1 reference

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Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit

14 June 2018

1 reference

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Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine

14 June 2018

1 reference

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Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

The time course of glutamate in the synaptic cleft

14 June 2018

1 reference

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Activity-dependent decrease in NMDA receptor responses during development of the visual cortex

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

Semiclosed Conformations of the Ligand-Binding Domains of NMDA Receptors during Stationary Gating

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

Synaptic NMDA receptors in basolateral amygdala principal neurons are triheteromeric proteins: physiological role of GluN2B subunits.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

NR2A subunit of the N-methyl D-aspartate receptors are required for potentiation at the mossy fiber to granule cell synapse and vestibulo-cerebellar motor learning.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

NR2A-/- mice lack long-term potentiation but retain NMDA receptor and L-type Ca2+ channel-dependent long-term depression in the juvenile superior colliculus.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

Developmental changes in distribution of NMDA receptor channel subunit mRNAs.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391998

10.1016/J.NEURON.2017.03.018

18 August 2018

Identifiers

DOI

1 reference

10 June 2018

PMCID

5391998

1 reference

10 June 2018

PubMed ID

28384476

1 reference

10 June 2018