Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders (Q41791619)

10 October 2017

Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders (English)

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Tripartite motif-containing 72

10 October 2017

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GOA release 2020-03-11

Insulin receptor

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Insulin receptor substrate 1

GOA release 2020-03-11

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GOA release 2020-03-11

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10

Li Jin

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10 October 2017

Ruisheng Song

1

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10 October 2017

Wei Peng

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Yan Zhang

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10 October 2017

Fengxiang Lv

4

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10 October 2017

Hong-Kun Wu

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10 October 2017

Jiaojiao Guo

6

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10 October 2017

Yongxing Cao

7

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10 October 2017

Yanbin Pi

8

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10 October 2017

Xin Zhang

9

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10 October 2017

Mao Zhang

11

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10 October 2017

Peng Jiang

12

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10 October 2017

Fenghua Liu

13

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10 October 2017

Shaoshuai Meng

14

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10 October 2017

Xiuqin Zhang

15

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10 October 2017

Ping Jiang

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10 October 2017

Chun-Mei Cao

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10 October 2017

Rui-Ping Xiao

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10 October 2017

language of work or name

English

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publication date

27 January 2013

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10 October 2017

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10 October 2017

494

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7437

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375-379

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https://scigraph.springernature.com/pub.10.1038/nature11834

10 October 2017

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cites work

The metabolic syndrome

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Developmental origins of the metabolic syndrome: prediction, plasticity, and programming

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Metabolic syndrome: connecting and reconciling cardiovascular and diabetes worlds

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Skeletal muscle insulin resistance is the primary defect in type 2 diabetes

21 January 2018

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Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

MG53 nucleates assembly of cell membrane repair machinery.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Rhesus macaques develop metabolic syndrome with reversible vascular dysfunction responsive to pioglitazone

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

21 January 2018

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Insulin signalling and the regulation of glucose and lipid metabolism

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Tissue-specific roles of IRS proteins in insulin signaling and glucose transport

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11834

Insulin receptors of skeletal muscle: Specific insulin binding sites and demonstration of decreased numbers of sites in obese rats

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11834

Grb10 mediates insulin-stimulated degradation of the insulin receptor: a mechanism of negative regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11834

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11834

The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11834

The SCF-Fbxo40 complex induces IRS1 ubiquitination in skeletal muscle, limiting IGF1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11834

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

21 January 2018

1 reference

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Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11834

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

21 January 2018

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12 December 2020

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

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12 December 2020

The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

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12 December 2020

Insulin resistance in spontaneously hypertensive rats. Difference in interpretation based on insulin infusion rate or on plasma insulin in glucose clamp studies.

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12 December 2020

MG53 constitutes a primary determinant of cardiac ischemic preconditioning

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12 December 2020

Identifiers

DOI

10.1038/NATURE11834

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Dimensions Publication ID

10 October 2017

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