Large-scale identification of genetic design strategies using local search (Q41764897)

9 October 2017

Large-scale identification of genetic design strategies using local search (English)

1 reference

9 October 2017

7

1 reference

9 October 2017

Michael Baym

4

0 references

George M. Church

object named as

George M Church

8

0 references

Bonnie Berger

6

object named as

Bonnie Berger

1 reference

9 October 2017

5

Jonathan A Kelner

1 reference

9 October 2017

Desmond S Lun

1

1 reference

PMCID

2736654

9 October 2017

Graham Rockwell

2

1 reference

PMCID

2736654

9 October 2017

Nicholas J Guido

3

1 reference

9 October 2017

18 August 2009

1 reference

Molecular Systems Biology

9 October 2017

1 reference

9 October 2017

5

1 reference

9 October 2017

296

1 reference

Natural computation meta-heuristics for the in silico optimization of microbial strains

9 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Systems metabolic engineering of Escherichia coli for L-threonine production

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Genome-scale analysis of Saccharomyces cerevisiae metabolism and ethanol production in fed-batch culture

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Thermodynamics-based metabolic flux analysis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Evolutionary programming as a platform for in silico metabolic engineering

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

OptStrain: a computational framework for redesign of microbial production systems.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Reconstruction and functional characterization of the human mitochondrial metabolic network based on proteomic and biochemical data

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Use of genome-scale microbial models for metabolic engineering

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Engineering the metabolism of Escherichia coli W3110 for the conversion of sugar to redox-neutral and oxidized products: homoacetate production

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Integrated energy and flux balance based multiobjective framework for large-scale metabolic networks.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Genome-scale in silico aided metabolic analysis and flux comparisons of Escherichia coli to improve succinate production.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

An optimization framework for identifying reaction activation/inhibition or elimination candidates for overproduction in microbial systems

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

In silico design and adaptive evolution of Escherichia coli for production of lactic acid.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Thermodynamic constraints for biochemical networks.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Minimal reaction sets for Escherichia coli metabolism under different growth requirements and uptake environments

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736654

Biotechnology of succinic acid production and markets for derived industrial products

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMSB.2009.57

Ab initio prediction of thermodynamically feasible reaction directions from biochemical network stoichiometry

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19690565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multi-Objective Optimization of Biological Networks for Prediction of Intracellular Fluxes

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMSB.2009.57

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/MSB.2009.57

1 reference

9 October 2017

1 reference

9 October 2017

1 reference

PMCID

2736654