HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term. (Q41762711)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22837194%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term (English)

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9 February 2020

1

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9 February 2020

Daniela Benati

2

1 reference

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9 February 2020

3

Olivier Lambotte

1 reference

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9 February 2020

10

William W Kwok

1 reference

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9 February 2020

13

Jacques Thèze

1 reference

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9 February 2020

11

Fabrice Lemaître

1 reference

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9 February 2020

author name string

Pierre de Truchis

4

1 reference

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9 February 2020

Laurence Slama

5

1 reference

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9 February 2020

Patricia Jeannin

6

1 reference

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9 February 2020

Moran Galperin

7

1 reference

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9 February 2020

Santiago Perez-Patrigeon

8

1 reference

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9 February 2020

Faroudy Boufassa

9

1 reference

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9 February 2020

Jean-François Delfraissy

12

1 reference

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9 February 2020

Lisa A Chakrabarti

14

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9 February 2020

language of work or name

English

0 references

publication date

25 July 2012

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9 February 2020

1 reference

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9 February 2020

volume

86

1 reference

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9 February 2020

page(s)

10661-10674

1 reference

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9 February 2020

issue

19

1 reference

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HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome

9 February 2020

cites work

1 reference

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HIV-specific CD4 T cell responses to different viral proteins have discordant associations with viral load and clinical outcome

6 June 2018

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T helper 17 cell heterogeneity and pathogenicity in autoimmune disease

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Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis

6 June 2018

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Responsiveness of HIV-specific CD4 T cells to PD-1 blockade

6 June 2018

1 reference

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CD4 dynamics over a 15 year-period among HIV controllers enrolled in the ANRS French observatory

6 June 2018

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HIV-specific CD4 T cells and immune control of viral replication

6 June 2018

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CD4+ T cells, including Th17 and cycling subsets, are intact in the gut mucosa of HIV-1-infected long-term nonprogressors

6 June 2018

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Antigen sensitivity and T-cell receptor avidity as critical determinants of HIV control

6 June 2018

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Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control

6 June 2018

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A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers

6 June 2018

1 reference

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Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

6 June 2018

1 reference

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SPICE: exploration and analysis of post-cytometric complex multivariate datasets

6 June 2018

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HIV-specific CD4+ T cells may contribute to viral persistence in HIV controllers

6 June 2018

1 reference

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Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers

6 June 2018

1 reference

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HIV infection, inflammation, immunosenescence, and aging

6 June 2018

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HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function

6 June 2018

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The elusive identity of T follicular helper cells

6 June 2018

1 reference

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HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses

6 June 2018

1 reference

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Regulation of virus-specific CD4+ T cell function by multiple costimulatory receptors during chronic HIV infection

6 June 2018

1 reference

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Immune mechanisms of HIV control

6 June 2018

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Th17 cell dynamics in HIV infection

6 June 2018

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Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control

6 June 2018

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Hepatitis C infection in HIV-1 natural viral suppressors.

6 June 2018

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HIV+ elite controllers have low HIV-specific T-cell activation yet maintain strong, polyfunctional T-cell responses

6 June 2018

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Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

6 June 2018

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T-cell exhaustion: characteristics, causes and conversion

6 June 2018

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HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity

6 June 2018

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Effector mechanisms in HIV-1 infected elite controllers: highly active immune responses?

6 June 2018

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Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells.

6 June 2018

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Human immunodeficiency virus type 1 escapes from interleukin-2-producing CD4+ T-cell responses without high-frequency fixation of mutations

6 June 2018

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Gag- and Nef-specific CD4+ T cells recognize and inhibit SIV replication in infected macrophages early after infection

6 June 2018

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Plasticity of CD4+ T cell lineage differentiation.

6 June 2018

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Prevalence and comparative characteristics of long-term nonprogressors and HIV controller patients in the French Hospital Database on HIV.

6 June 2018

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A vital role for interleukin-21 in the control of a chronic viral infection

6 June 2018

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IL-21 is required to control chronic viral infection

6 June 2018

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Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population.

6 June 2018

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IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

6 June 2018

1 reference

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Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control

6 June 2018

1 reference

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Emerging concepts in the immunopathogenesis of AIDS

6 June 2018

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Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

6 June 2018

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A fundamental role for interleukin-21 in the generation of T follicular helper cells

6 June 2018

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Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection.

6 June 2018

1 reference

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Virus-specific interleukin-17-producing CD4+ T cells are detectable in early human immunodeficiency virus type 1 infection

6 June 2018

1 reference

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Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

6 June 2018

1 reference

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Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy

6 June 2018

1 reference

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Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study

6 June 2018

1 reference

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Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy

6 June 2018

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IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner

6 June 2018

1 reference

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Human immunodeficiency virus type 1 controllers but not noncontrollers maintain CD4 T cells coexpressing three cytokines

6 June 2018

1 reference

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HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype

6 June 2018

1 reference

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Changes in paracrine interleukin-2 requirement, CCR7 expression, frequency, and cytokine secretion of human immunodeficiency virus-specific CD4+ T cells are a consequence of antigen load

6 June 2018

1 reference

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Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation

6 June 2018

1 reference

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

6 June 2018

1 reference

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Functional signatures of protective antiviral T-cell immunity in human virus infections.

6 June 2018

1 reference

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Expansion and contraction of HIV-specific CD4 T cells with short bursts of viremia, but physical loss of the majority of these cells with sustained viral replication

6 June 2018

1 reference

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Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment

6 June 2018

1 reference

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HIV-1-specific CD4+ T lymphocyte turnover and activation increase upon viral rebound

6 June 2018

1 reference

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Limited durability of viral control following treated acute HIV infection

6 June 2018

1 reference

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Detection of low-frequency human antigen-specific CD4(+) T cells using MHC class II multimer bead sorting and immunoscope analysis.

6 June 2018

1 reference

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Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides

6 June 2018

1 reference

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MHC Class II tetramers and the pursuit of antigen-specific T cells: define, deviate, delete

6 June 2018

1 reference

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HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity

6 June 2018

1 reference

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Challenges in staining T cells using HLA class II tetramers

6 June 2018

1 reference

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MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen

6 June 2018

1 reference

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Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

6 June 2018

1 reference

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HIV-specific IL-21 producing CD4+ T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control.

6 June 2018

1 reference

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HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells.

18 August 2018

1 reference

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Immune and virological benefits of 10 years of permanent viral control with antiretroviral therapy.

18 August 2018

1 reference

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Dynamics and consequences of IL-21 production in HIV-infected individuals: a longitudinal and cross-sectional study.

18 August 2018

1 reference

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Persistent low-level viremia in HIV-1 elite controllers and relationship to immunologic parameters

18 August 2018

1 reference

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Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses

18 August 2018

1 reference

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Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.

18 August 2018

1 reference

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Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

18 August 2018

1 reference

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HIV-specific CD4+ T cells and viremia: who's in control?

18 August 2018

1 reference

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Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy

18 August 2018

1 reference

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HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457309

Characteristics, Determinants, and Clinical Relevance of CD4 T Cell Recovery to <500 Cells/ L in HIV Type 1--Infected Individuals Receiving Potent Antiretroviral Therapy

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457309

Predictors of Immunological Failure after Initial Response to Highly Active Antiretroviral Therapy in HIV‐1–Infected Adults: A EuroSIDA Study

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457309

Loss of HIV-1-specific T cell proliferation in chronic HIV-1 infection: cause or consequence of viral replication?

2 December 2018

1 reference

12 December 2020

The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells

1 reference

12 December 2020

Cytotoxic granule release dominates gag-specific CD4+ T-cell response in different phases of HIV infection

1 reference

12 December 2020

Long-term non-progressors display a greater number of Th17 cells than HIV-infected typical progressors

1 reference

12 December 2020

Characterization of CD4(+) CTLs ex vivo

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.00056-12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22837194%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22837194%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference