Identification and characterization of novel factors that act in the nonsense-mediated mRNA decay pathway in nematodes, flies and mammals. (Q41752171)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25452588%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Identification and characterization of novel factors that act in the nonsense-mediated mRNA decay pathway in nematodes, flies and mammals (English)

1 reference

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Upf1 RNA helicase Dmel_CG1559

23 February 2020

main subject

1 reference

GOA release 2020-03-11

author

Javier Caceres

7

1 reference

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23 February 2020

author name string

Angela Casadio

1

1 reference

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23 February 2020

Dasa Longman

2

1 reference

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23 February 2020

Nele Hug

3

1 reference

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23 February 2020

Laurent Delavaine

4

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23 February 2020

Raúl Vallejos Baier

5

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23 February 2020

Claudio R Alonso

6

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23 February 2020

publication date

1 December 2014

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23 February 2020

1 reference

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23 February 2020

volume

16

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23 February 2020

issue

1

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23 February 2020

page(s)

71-78

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Organizing principles of mammalian nonsense-mediated mRNA decay

23 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans

6 June 2018

1 reference

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Regulation of nonsense-mediated mRNA decay: implications for physiology and disease

6 June 2018

1 reference

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Nonsense-mediated mRNA decay - mechanisms of substrate mRNA recognition and degradation in mammalian cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Autoregulation of the nonsense-mediated mRNA decay pathway in human cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.

6 June 2018

1 reference

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Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2

6 June 2018

1 reference

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Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner

6 June 2018

1 reference

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Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Cutting the nonsense: the degradation of PTC-containing mRNAs

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Nonsense-mediated mRNA decay (NMD) mechanisms

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Tools for neuroanatomy and neurogenetics in Drosophila

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

An alternative branch of the nonsense-mediated decay pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

The nonsense-mediated decay RNA surveillance pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Rab27 and its effectors in secretory granule exocytosis: a novel docking machinery composed of a Rab27.effector complex

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Functional genomic analysis of C. elegans molting

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Isolation and Characterization of High-Temperature-Induced Dauer Formation Mutants in Caenorhabditis elegans

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

A Hox gene mutation that triggers nonsense-mediated RNA decay and affects alternative splicing during Drosophila development

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits

6 June 2018

1 reference

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Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

6 June 2018

1 reference

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Human SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulum

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

nompA encodes a PNS-specific, ZP domain protein required to connect mechanosensory dendrites to sensory structures

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304730

18 August 2018

Identifiers

DOI

10.15252/EMBR.201439183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25452588%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25452588%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25452588%20AND%20SRC:MED&resulttype=core&format=json