Pathways for protein folding: is a new view needed? (Q41728306)

8 October 2017

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title

Pathways for protein folding: is a new view needed? (English)

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8 October 2017

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4

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8 October 2017

Pande VS

1

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PubMed ID

9519298

8 October 2017

Grosberg AYu

series ordinal

2

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PubMed ID

9519298

8 October 2017

Tanaka T

series ordinal

3

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8 October 2017

1 February 1998

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Current Opinion in Structural Biology

8 October 2017

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8 October 2017

8

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8 October 2017

68-79

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8 October 2017

1

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A lattice statistical mechanics model of the conformational and sequence spaces of proteins

8 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Theoretical Studies of Protein Folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Protein folding bottlenecks: A lattice Monte Carlo simulation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Engineering of stable and fast-folding sequences of model proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Kinetics and thermodynamics of folding in model proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Thermodynamic procedure to synthesize heteropolymers that can renature to recognize a given target molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Protein folding funnels: the nature of the transition state ensemble

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Comparing folding codes for proteins and polymers.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

From structure to sequence and back again.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Improved design of stable and fast-folding model proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Modeling protein folding: the beauty and power of simplicity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Design of proteins with selected thermal properties

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Folding simulations and computer redesign of protein A three-helix bundle motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

New algorithm for protein design.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

On the theory of folding kinetics for short proteins.

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https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Computer simulation of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Dynamic Monte Carlo simulations of globular protein folding/unfolding pathways. I. Six-member, Greek key beta-barrel proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Computer modeling and folding of four-helix bundles

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

On the origin of the cooperativity of protein folding: implications from model simulations

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Kinetics and thermodynamics of folding of a de novo designed four-helix bundle protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Denaturants can accelerate folding rates in a class of globular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Protein folding kinetics: timescales, pathways and energy landscapes in terms of sequence-dependent properties

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Is the molten globule a third phase of proteins?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Molecular dynamics simulation of protein denaturation: solvation of the hydrophobic cores and secondary structure of barnase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Characterization of the transition state of protein unfolding by use of molecular dynamics: chymotrypsin inhibitor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Molecular dynamics simulations of protein unfolding and limited refolding: characterization of partially unfolded states of ubiquitin in 60% methanol and in water

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Investigation of protein unfolding and stability by computer simulation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

First-principles calculation of the folding free energy of a three-helix bundle protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Molecular dynamics simulations of the unfolding of barnase in water and 8 M aqueous urea

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Spin glasses and the statistical mechanics of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Phase diagram of random copolymers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Freezing transition of random heteropolymers consisting of an arbitrary set of monomers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Chain Length Scaling of Protein Folding Time

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Statistics of kinetic pathways on biased rough energy landscapes with applications to protein folding.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Is heteropolymer freezing well described by the random energy model?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Navigating the folding routes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Influence of point mutations on protein structure: probability of a neutral mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Proteins with selected sequences fold into unique native conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Characterization of a helical protein designed from first principles

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

De novo design, expression, and characterization of Felix: a four-helix bundle protein of native-like sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Cooperatively folded proteins in random sequence libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Protein design automation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

De novo design of the hydrophobic core of ubiquitin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Proteins from scratch.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

How does a protein fold?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Theoretical studies of protein-folding thermodynamics and kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Statistical mechanics of proteins with "evolutionary selected" sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

The molten globule is a third thermodynamical state of protein molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

All-or-none solvent-induced transitions between native, molten globule and unfolded states in globular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Two-state models of protein folding kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Structures of folding intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Structural energetics of the molten globule state

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Protein folding funnels: a kinetic approach to the sequence-structure relationship

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Funnels, pathways, and the energy landscape of protein folding: a synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Toward an outline of the topography of a realistic protein-folding funnel

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Structural correlations in protein folding funnels

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

From Levinthal to pathways to funnels

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Specific intermediates in the folding reactions of small proteins and the mechanism of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Mechanism of folding of ribonuclease A. Slow refolding is a sequential reaction via structural intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Pathways of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Kinetics of protein folding. A lattice model study of the requirements for folding to the native state.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Simple model of protein folding kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Kinetics of a Gaussian random copolymer as a prototype for protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Motion of polymer ends in homopolymer and heteropolymer collapse

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

On the transition coordinate for protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Nucleation mechanisms in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Specific nucleus as the transition state for protein folding: evidence from the lattice model.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Conserved residues and the mechanism of protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Partially folded states of proteins: characterization by X-ray scattering

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Optimization of rates of protein folding: the nucleation-condensation mechanism and its implications

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Nucleation, rapid folding, and globular intrachain regions in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Protein-folding dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Characterizing transition states in protein folding: an essential step in the puzzle

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Rate of protein folding near the point of thermodynamic equilibrium between the coil and the most stable chain fold

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Local interactions dominate folding in a simple protein model.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

An analysis of protein folding pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

A sequential model of nucleation-dependent protein folding: Kinetic studies of ribonuclease A

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Is there a single pathway for the folding of a polypeptide chain?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Single versus parallel pathways of protein folding and fractional formation of structure in the transition state

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Exploring the energy surface of protein folding by structure-reactivity relationships and engineered proteins: observation of Hammond behavior for the gross structure of the transition state and anti-Hammond behavior for structural elements for unfo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

The barriers in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Submillisecond folding of monomeric lambda repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Extremely rapid protein folding in the absence of intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Kinetic and equilibrium intermediates in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Understanding how proteins fold: the lysozyme story so far.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Formation of a molten globule intermediate early in the kinetic folding pathway of apomyoglobin.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

The kinetic folding intermediate of ribonuclease H resembles the acid molten globule and partially unfolded molecules detected under native conditions.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

The roles of partly folded intermediates in protein folding.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Universality and diversity of the protein folding scenarios: a comprehensive analysis with the aid of a lattice model

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Absence of a stable intermediate on the folding pathway of protein A.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

Matching speed and stability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

The nature of protein folding pathways: the classical versus the new view

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-440X%2898%2980012-2

1 reference

7 January 2021

10.1016/S0959-440X(98)80012-2

Identifiers

DOI

1 reference

8 October 2017

1 reference

PubMed ID

9519298