The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates (Q41724238)

8 October 2017

The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates (English)

1 reference

8 October 2017

1 reference

N Serkova

1

1 reference

8 October 2017

L Litt

2

1 reference

8 October 2017

D Leibfritz

3

1 reference

8 October 2017

B Hausen

4

1 reference

8 October 2017

R E Morris

5

1 reference

8 October 2017

T L James

6

1 reference

8 October 2017

L Z Benet

7

1 reference

8 October 2017

U Christians

8

1 reference

8 October 2017

language of work or name

English

0 references

publication date

1 February 2000

1 reference

British Journal of Pharmacology

8 October 2017

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8 October 2017

129

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8 October 2017

3

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8 October 2017

485-492

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Cyclosporine neurotoxicity: a review

8 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Evaluation of individual and combined neurotoxicity of the immunosuppressants cyclosporine and sirolimus by in vitro multinuclear NMR spectroscopy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Suppression of acute rejection in allogeneic rat lung transplantation: a study of the efficacy and pharmacokinetics of rapamycin derivative (SDZ RAD) used alone and in combination with a microemulsion formulation of cyclosporine

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p

6 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

6 June 2018

https://api.crossref.org/works/10.1038%2FSJ.BJP.0703079

7 January 2021

inferred from DOI database lookup

In vitro and in situ absorption of SDZ-RAD using a human intestinal cell line (Caco-2) and a single pass perfusion model in rats: comparison with rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Cytochrome P450 in the brain: 2B or not 2B.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Central nervous system complications after lung transplantation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Modulation of energy status and cytotoxicity induced by FK506 and cyclosporin A in a renal epithelial cell line

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

SDZ RAD, a new rapamycin derivative: pharmacological properties in vitro and in vivo

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Mitochondrial permeability transition in the central nervous system: induction by calcium cycling-dependent and -independent pathways.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Evaluation of the effects of immunosuppressants on neuronal and glial cells in vitro by multinuclear magnetic resonance spectroscopy.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Cyclosporine neurotoxicity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Differential effects of creatine depletion on the regulation of enzyme activities and on creatine-stimulated mitochondrial respiration in skeletal muscle, heart, and brain

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Lake Louise Consensus Conference on cyclosporin monitoring in organ transplantation: report of the consensus panel.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Cyclosporine nephrotoxicity: attenuation by an antioxidant-inhibitor of lipid peroxidation in vitro and in vivo.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Changes in ATP after cyclosporin A treatment in a renal epithelial cell line in the rat studied by 31P-NMR spectroscopy.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Regulation of cellular energy metabolism

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Reversibility of acute alcohol cardiac depression: 31 P NMR in hamsters

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Central nervous system toxicity after liver transplantation. The role of cyclosporine and cholesterol.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Tolerance of low intracellular pH during hypercapnia by rat cortical brain slices: A 31P/1H NMR study

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

The restoration of ATP synthesis may explain the protective effect of calcium antagonists against cyclosporine a nephrotoxicity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

A Method for Testing for Synergy with Any Number of Agents

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Cyclosporine metabolism in human liver: identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

The in vivo effect of rapamycin derivative SDZ RAD on lymphocyte proliferation.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

alpha-Lipoic acid: a metabolic antioxidant which regulates NF-kappa B signal transduction and protects against oxidative injury

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571863

Cyclosporine a inhibits ATP net uptake of rat kidney mitochondria

3 November 2018

1 reference

12 December 2020

Cyclosporine-associated central-nervous-system toxicity after allogeneic bone-marrow transplantation

1 reference

12 December 2020

NEUROLOGICAL COMPLICATIONS FOLLOWING LIVER TRANSPLANTATION

1 reference

12 December 2020

Effect of cyclosporine on oxidative phosphorylation and adenylate energy charge of regenerating rat liver

1 reference

12 December 2020

Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes

1 reference

12 December 2020

Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition

1 reference

12 December 2020

Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity

1 reference

12 December 2020

Sensitive and specific quantification of sirolimus (rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray-mass spectrometry

1 reference

12 December 2020

Cyclosporine A-induced oxidative stress in rat hepatocytes

1 reference

12 December 2020

SDZ RAD, a new rapamycin derivative: synergism with cyclosporine

1 reference

12 December 2020

Assessment of the mechanism of astrocyte swelling induced by the macrolide immunosuppressant sirolimus using multinuclear nuclear magnetic resonance spectroscopy

1 reference

12 December 2020

The macrolide SDZ RAD is efficacious in a nonhuman primate model of allotransplantation

1 reference

12 December 2020

Effect of SDZ RAD on transplant arteriosclerosis in the rat aortic model

1 reference

12 December 2020

Effects of rapamycin analogue SDZ RAD on obliterative lesions in a porcine heterotopic bronchial allograft model

1 reference

12 December 2020

Immunophilins in the nervous system

1 reference

12 December 2020

Absorption and intestinal metabolism of SDZ-RAD and rapamycin in rats

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0703079

1 reference

8 October 2017

1 reference

8 October 2017

1 reference