The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity (Q41715749)

7 October 2017

The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase activity (English)

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7 October 2017

Morimoto AM

1

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7 October 2017

Tomlinson MG

2

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7 October 2017

Nakatani K

3

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7 October 2017

Bolen JB

4

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7 October 2017

Roth RA

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7 October 2017

Herbst R

6

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7 October 2017

language of work or name

English

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publication date

1 January 2000

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7 October 2017

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7 October 2017

19

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7 October 2017

200-209

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7 October 2017

2

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203288

7 October 2017

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cites work

The akt kinase: molecular determinants of oncogenicity

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Signal transduction for proliferation of glioma cells in vitro occurs predominantly through a protein kinase C-mediated pathway.

21 January 2018

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A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain

21 January 2018

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Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

21 January 2018

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Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.

21 January 2018

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Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

21 January 2018

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Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

21 January 2018

1 reference

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Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

21 January 2018

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PTEN1 is frequently mutated in primary endometrial carcinomas

21 January 2018

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Inhibition of phospholipase C-gamma1 activation blocks glioma cell motility and invasion of fetal rat brain aggregates

21 January 2018

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PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

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Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

21 January 2018

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Germline mutations in PTEN are present in Bannayan-Zonana syndrome.

21 January 2018

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

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P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

21 January 2018

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The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

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Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase

21 January 2018

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Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

21 January 2018

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Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression

21 January 2018

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Regulation of phosphoinositide-specific phospholipase C isozymes

21 January 2018

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Overactivation of phospholipase C-gamma1 renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis.

21 January 2018

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

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Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

21 January 2018

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Activated platelet-derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line

21 January 2018

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The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

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Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity

21 January 2018

1 reference

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Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

21 January 2018

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Lipid-Regulated Kinases: Some Common Themes at Last

21 January 2018

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High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

21 January 2018

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Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203288

inferred from DOI database lookup

7 January 2021

based on heuristic

Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203288

inferred from DOI database lookup

7 January 2021

based on heuristic

Phosphoinositide 3-kinase regulates phospholipase Cgamma-mediated calcium signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203288

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1203288

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Dimensions Publication ID

7 October 2017

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