Recombinant human interferon-gamma. Differences in glycosylation and proteolytic processing lead to heterogeneity in batch culture (Q41712973)

7 October 2017

Recombinant human interferon-gamma. Differences in glycosylation and proteolytic processing lead to heterogeneity in batch culture (English)

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7 October 2017

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Curling EM

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7 October 2017

Hayter PM

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7 October 2017

Baines AJ

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7 October 2017

Bull AT

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7 October 2017

Gull K

5

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7 October 2017

Strange PG

6

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7 October 2017

Jenkins N

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7 October 2017

language of work or name

English

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publication date

1 December 1990

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7 October 2017

5

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inferred from page(s)

published in

Biochemical Journal

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7 October 2017

272

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7 October 2017

2

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7 October 2017

333-337

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Synthesis and processing of asparagine-linked oligosaccharides

7 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Inducible expression of amplified human beta interferon genes in CHO cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Carbohydrate-Specific Receptors of the Liver

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Expression of human immune interferon cDNA in E. coli and monkey cells.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Resistance to Recombinant Interferon Alfa-2a in Hairy-Cell Leukemia Associated with Neutralizing Anti-Interferon Antibodies

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Inhibitors of the biosynthesis and processing of N-linked oligosaccharide chains

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Comparative study of the asparagine-linked sugar chains of natural human interferon-beta 1 and recombinant human interferon-beta 1 produced by three different mammalian cells.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Human interferon-gamma lacking 23 COOH-terminal amino acids is biologically active.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

The antichlamydial, antiviral, and antiproliferative activities of human gamma interferon are dependent on the integrity of the C terminus of the interferon molecule.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Differential purification by immunoaffinity chromatography of two carboxy-terminal portion-deleted derivatives of recombinant human interferon-gamma from Escherichia coli.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Role of polycationic C-terminal portion in the structure and activity of recombinant human interferon-gamma.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Characterization of four different mammalian-cell-derived recombinant human interferon-beta 1s. Identical polypeptides and non-identical carbohydrate moieties compared to natural ones

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Amino terminus is essential to the structural integrity of recombinant human interferon-gamma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

The role of the asparagine-linked oligosaccharides of the alpha subunit in the secretion and assembly of human chorionic gonadotrophin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Source of heterogeneity in secreted interferon-gamma. A study on products of translation in vitro

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Growth-dependent alterations in oligomannosyl glycopeptides expressed in Sindbis virus glycoproteins

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149704

Effects of glycosidase treatment on the physicochemical properties and biological activity of human interferon-gamma

18 August 2018

1 reference

12 December 2020

Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation

1 reference

12 December 2020

Natural murine interferon-gamma. Evidence for post-translational proteolytic processing

1 reference

12 December 2020

Structural studies of the carbohydrate chains of human gamma-interferon

1 reference

12 December 2020

Heterogeneity of Chinese hamster ovary cell-produced recombinant murine interferon-gamma

1 reference

12 December 2020

Monoclonal antibodies to human interferon-gamma. II: Antibodies with neutralizing activity

1 reference

12 December 2020

Evidence for a polypeptide segment at the carboxyl terminus of recombinant human gamma interferon involved in expression of biological activity

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12 December 2020

Glycosylation at specific sites of erythropoietin is essential for biosynthesis, secretion, and biological function

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2720333

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7 October 2017

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7 October 2017

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