A cluster of mutations in HLA-A2 alpha 2 helix abolishes peptide recognition by T cells (Q41703499)

7 October 2017

title

A cluster of mutations in HLA-A2 alpha 2 helix abolishes peptide recognition by T cells (English)

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7 October 2017

R J Moots

1

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7 October 2017

M Matsui

2

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7 October 2017

L Pazmany

3

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7 October 2017

A J McMichael

4

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7 October 2017

J A Frelinger

5

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7 October 2017

language of work or name

English

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publication date

1 January 1991

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7 October 2017

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7 October 2017

volume

34

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7 October 2017

issue

3

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7 October 2017

page(s)

141-148

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Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. I. Generation and recognition of virus strains and H-2b mutants

7 October 2017

cites work

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12 December 2020

NK susceptibility varies inversely with target cell class I HLA antigen expression.

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12 December 2020

Domain interactions of H–2 class I antigens alter cytotoxic T-cell recognition sites

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12 December 2020

Saturation mutagenesis of a major histocompatibility complex protein domain: identification of a single conserved amino acid important for allorecognition

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12 December 2020

Analysis of the molecular basis of HLA-A3 recognition by cytotoxic T cells using defined mutants of the HLA-A3 molecule

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12 December 2020

The complete primary structure of HLA-Bw58

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12 December 2020

Evidence of widespread binding of HLA class I molecules to peptides

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12 December 2020

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

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12 December 2020

Rapid and efficient site-specific mutagenesis without phenotypic selection

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12 December 2020

Identification by site-directed mutagenesis of amino acid residues contributing to serologic and CTL-defined epitope differences between HLA-A2.1 and HLA-A2.3.

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12 December 2020

Recognition of Db and Kb gene products by influenza-specific cytotoxic T cells

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12 December 2020

Assembly of MHC class I molecules analyzed in vitro

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12 December 2020

A study of functionally active amino acids involved in the interaction of HLA-A2 or HLA-A3 molecules with cytolytic T lymphocytes

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12 December 2020

Apparent lack of MHC restriction in binding of class I HLA molecules to solid-phase peptides

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12 December 2020

Nature of polymorphism in HLA-A, -B, and -C molecules

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12 December 2020

Direct binding of influenza peptides to class I HLA molecules

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12 December 2020

Specificity and regulation of cytotoxic T-lymphocyte responses analyzed with H-2 mutants

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12 December 2020

Analysis of novel residues of class I involved in recognition by alloreactive T cells

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12 December 2020

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

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12 December 2020

Structure of the human class I histocompatibility antigen, HLA-A2

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12 December 2020

A panel of unique HLA-A2 mutant molecules define epitopes recognized by HLA-A2-specific antibodies and cytotoxic T lymphocytes

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12 December 2020

Effect of mutations and variations of HLA-A2 on recognition of a virus peptide epitope by cytotoxic T lymphocytes

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12 December 2020

Cytotoxic T lymphocyte-defined epitope differences between HLA-A2.1 and HLA-A2.2 map to two distinct regions of the molecule.

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12 December 2020

Comparison between two peptide epitopes presented to cytotoxic T lymphocytes by HLA-A2. Evidence for discrete locations within HLA-A2

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12 December 2020

A single amino acid substitution in HLA-A2 can alter the selection of the cytotoxic T lymphocyte repertoire that responds to influenza virus matrix peptide 55-73.

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12 December 2020

Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2.

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12 December 2020

Physical association between MHC class I molecules and immunogenic peptides

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12 December 2020

Exon shuffling in vivo can generate novel HLA class I molecules

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12 December 2020

Mutations in the α1 domain of a class I gene define residues important for specific allorecognition

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12 December 2020

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

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12 December 2020

Direct demonstration that cytotoxic T lymphocytes recognize conformational determinants and not primary amino acid sequences

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12 December 2020

Differential effects of amino acid substitutions in the beta-sheet floor and alpha-2 helix of HLA-A2 on recognition by alloreactive viral peptide-specific cytotoxic T lymphocytes.

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12 December 2020

Cross-reactivity patterns of vaccinia-specific cytotoxic T lymphocytes from H-2K b mutants

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12 December 2020

A complete library of point substitution mutations in the glucocorticoid response element of mouse mammary tumor virus

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12 December 2020

Murine major histocompatibility complex class-I mutants: molecular analysis and structure-function implications

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12 December 2020

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

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12 December 2020

Mutations in the alpha 2 helix of HLA-A2 affect presentation but do not inhibit binding of influenza virus matrix peptide

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12 December 2020

H-2Kb mutations limit the CTL response to SV40 TASA

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12 December 2020

Specificity pockets for the side chains of peptide antigens in HLA-Aw68

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12 December 2020

Alloreactive cytolytic T-cell clones preferentially recognize conformational determinants on histocompatibility antigens: analysis with genetically engineered hybrid antigens

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12 December 2020

Allogeneic and associative recognition determinants of H-2 molecules

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12 December 2020

Homoeo-domain homology in yeast MAT alpha 2 is essential for repressor activity

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12 December 2020

A monoclonal antibody that recognizes an antigenic determinant shared by HLA A2 and B17.

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12 December 2020

Identifiers

DOI

10.1007/BF00205816

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7 October 2017

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