A general approach to antibody thermostabilization (Q41679322)

7 October 2017

A general approach to antibody thermostabilization (English)

1 reference

7 October 2017

Audrey D McConnell

1

1 reference

7 October 2017

Xue Zhang

2

1 reference

7 October 2017

John L Macomber

3

1 reference

7 October 2017

Betty Chau

4

1 reference

7 October 2017

Joseph C Sheffer

5

1 reference

7 October 2017

Sorena Rahmanian

6

1 reference

7 October 2017

Eric Hare

7

1 reference

7 October 2017

Vladimir Spasojevic

8

1 reference

7 October 2017

Robert A Horlick

9

1 reference

7 October 2017

David J King

10

1 reference

7 October 2017

Peter M Bowers

11

1 reference

7 October 2017

1 January 2014

1 reference

7 October 2017

9

1 reference

based on heuristic

inferred from page(s)

published in

Monoclonal Antibodies

1 reference

7 October 2017

6

1 reference

7 October 2017

5

1 reference

7 October 2017

1274-1282

1 reference

Toward aggregation-resistant antibodies by design

7 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Mutational analysis of 48G7 reveals that somatic hypermutation affects both antibody stability and binding affinity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Structure-based design of supercharged, highly thermoresistant antibodies

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Rugged single domain antibody detection elements for Bacillus anthracis spores and vegetative cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Beyond natural antibodies: the power of in vitro display technologies

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Design of therapeutic proteins with enhanced stability.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Antibody production, design and use for biosensor-based applications

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Engineered human antibody constant domains with increased stability

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Single-domain antibodies as building blocks for novel therapeutics

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Comprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domains

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Supercharging proteins can impart unusual resilience

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Biophysical properties of human antibody variable domains

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Selection for improved protein stability by phage display.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Engineering the isoelectric point of a renal cell carcinoma targeting antibody greatly enhances scFv solubility

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Stabilization of antibody fragments in adverse environments

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Engineering antibodies for imaging and therapy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Relationship between thermal stability, degradation rate and expression yield of barnase variants in the periplasm of Escherichia coli.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

A broad range of Fab stabilities within a host of therapeutic IgGs.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Consensus-based engineering of protein stability: from intrabodies to thermostable enzymes.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

An integrated approach to extreme thermostabilization and affinity maturation of an antibody

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623350

Engineering Aggregation Resistance in IgG by Two Independent Mechanisms: Lessons from Comparison of Pichia pastoris and Mammalian Cell Expression

3 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FMABS.29680

Aggregation-resistant domain antibodies selected on phage by heat denaturation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25517312

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Aggregation-resistant domain antibodies engineered with charged mutations near the edges of the complementarity-determining regions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25517312

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/MABS.29680

1 reference

7 October 2017

1 reference

7 October 2017

1 reference