MiR-873 regulates ERα transcriptional activity and tamoxifen resistance via targeting CDK3 in breast cancer cells (Q41660033)

6 October 2017

MiR-873 regulates ERα transcriptional activity and tamoxifen resistance via targeting CDK3 in breast cancer cells (English)

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6 October 2017

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J Cui

1

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6 October 2017

Y Yang

2

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6 October 2017

H Li

3

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6 October 2017

Y Leng

4

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6 October 2017

K Qian

5

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6 October 2017

Q Huang

6

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6 October 2017

C Zhang

7

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6 October 2017

Z Lu

8

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6 October 2017

J Chen

9

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6 October 2017

T Sun

10

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6 October 2017

R Wu

11

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6 October 2017

Y Sun

12

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6 October 2017

H Song

13

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6 October 2017

X Wei

14

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6 October 2017

P Jing

15

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6 October 2017

X Yang

16

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6 October 2017

C Zhang

17

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6 October 2017

language of work or name

English

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publication date

22 December 2014

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6 October 2017

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34

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30

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6 October 2017

3895-3907

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https://scigraph.springernature.com/pub.10.1038/onc.2014.430

6 October 2017

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Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: implications for treatment of advanced disease.

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MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1

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Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer

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Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer.

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Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene

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Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

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Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex

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Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation

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Roscovitine, a selective CDK inhibitor, reduces the basal and estrogen-induced phosphorylation of ER-α in human ER-positive breast cancer cells

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Tamoxifen downregulation of miR-451 increases 14-3-3ζ and promotes breast cancer cell survival and endocrine resistance.

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A role for estrogen receptor phosphorylation in the resistance to tamoxifen

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Estrogen receptor-alpha phosphorylation at serine-118 and tamoxifen response in breast cancer

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Molecular changes associated with the agonist activity of hydroxy-tamoxifen and the hyper-response to estradiol in hydroxy-tamoxifen-resistant breast cancer cell lines

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Kinase-specific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity

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Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptor-mediated gene transcription and breast cancer cell growth

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FBI-1 functions as a novel AR co-repressor in prostate cancer cells

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Cyclin-dependent kinase-3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation.

21 January 2018

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Phosphorylation of ERα at serine 118 in primary breast cancer and in tamoxifen-resistant tumours is indicative of a complex role for ERα phosphorylation in breast cancer progression

21 January 2018

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CDK3 expression and its clinical significance in human nasopharyngeal carcinoma

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Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25531331

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25531331

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.430

1 reference

Dimensions Publication ID

6 October 2017

1033351931

0 references

Fatcat ID

release_b5f2tsxy5reepijdi56u2f6te4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/b5f2tsxy5reepijdi56u2f6te4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference