Genotypic selection methods for the direct analysis of point mutations (Q41645720)

6 October 2017

title

Genotypic selection methods for the direct analysis of point mutations (English)

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ORCID Public Data File 2021

6 October 2017

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author name string

Parsons BL

series ordinal

1

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6 October 2017

Heflich RH

series ordinal

2

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6 October 2017

publication date

1 October 1997

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6 October 2017

language of work or name

0 references

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6 October 2017

volume

387

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6 October 2017

issue

2

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6 October 2017

page(s)

97-121

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publication type of scholarly work

6 October 2017

review article

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Using the polymerase chain reaction to estimate mutation frequencies and rates in human cells

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The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages

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7 January 2021

Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans

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7 January 2021

A rapid and sensitive PCR screening method for point mutations associated with mitochondrial encephalomyopathies

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7 January 2021

A new point mutation at nucleotide pair 3291 of the mitochondrial tRNA(Leu(UUR)) gene in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS)

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7 January 2021

Fidelity of DNA polymerases in DNA amplification

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Fidelity of Thermococcus litoralis DNA polymerase (Vent) in PCR determined by denaturing gradient gel electrophoresis

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7 January 2021

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A genotypic mutation system measuring mutations in restriction recognition sequences.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Detection of minority point mutations by modified PCR technique: a new approach for a sensitive diagnosis of tumor-progression markers

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7 January 2021

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7 January 2021

MutS binding protects heteroduplex DNA from exonuclease digestion in vitro: a simple method for detecting mutations

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Evaluation of MutS as a tool for direct measurement of point mutations in genomic DNA.

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Detection of point mutations in codon 331 of mitochondrial NADH dehydrogenase subunit 2 in Alzheimer's brains

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7 January 2021

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7 January 2021

Simple and sensitive detection of mutations in the ras proto-oncogenes using PNA-mediated PCR clamping

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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'Cold SSCP': a simple, rapid and non-radioactive method for optimized single-strand conformation polymorphism analyses

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Screening for mutations by RNA single-strand conformation polymorphism (rSSCP): comparison with DNA-SSCP

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7 January 2021

Optimization of the single-strand conformation polymorphism (SSCP) technique for detection of point mutations

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7 January 2021

Sensitivity of single-strand conformation polymorphism and heteroduplex method for mutation detection in the cystic fibrosis gene

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7 January 2021

DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory

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7 January 2021

Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis

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7 January 2021

Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes

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7 January 2021

Comprehensive detection of single base changes in human genomic DNA using denaturing gradient gel electrophoresis and a GC clamp

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7 January 2021

Molecular analysis of complex human cell populations: mutational spectra of MNNG and ICR-191.

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7 January 2021

Analysis of point mutations induced by ultraviolet light in human cells

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7 January 2021

Mutational spectra in human B-cells. Spontaneous, oxygen and hydrogen peroxide-induced mutations at the hprt gene

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7 January 2021

Mutational spectrometry: a general approach for hot-spot point mutations in selectable genes

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7 January 2021

Determination of point mutational spectra of benzo[a]pyrene-diol epoxide in human cells

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7 January 2021

Mutational analysis using denaturing gradient gel electrophoresis and PCR

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7 January 2021

Mutational spectrum of chromium(VI) in human cells

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7 January 2021

Androgen receptor gene mutations in human prostate cancer

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7 January 2021

Activation of the c-Ki-ras oncogene in aflatoxin B1-induced hepatocellular carcinoma and adenoma in the rat: detection by denaturing gradient gel electrophoresis

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7 January 2021

Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA

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7 January 2021

Phylogenetic relationships of Thiomicrospira species and their identification in deep-sea hydrothermal vent samples by denaturing gradient gel electrophoresis of 16S rDNA fragments

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7 January 2021

Constant denaturant capillary electrophoresis (CDCE): a high resolution approach to mutational analysis

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7 January 2021

Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection

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7 January 2021

Comparison of DGGE and CDGE in detection of single base changes in the hamster hprt and human N-ras genes

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7 January 2021

Rapid separation and purification of oligonucleotides by high-performance capillary gel electrophoresis

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7 January 2021

Analysis of polymerase chain reaction product by capillary electrophoresis and its application to the detection of single base substitution in genes

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7 January 2021

Detection and quantitation of mutant K-ras codon 12 restriction fragments by capillary electrophoresis

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7 January 2021

Separation of DNA fragments by capillary electrophoresis using replaceable linear polyacrylamide matrices

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7 January 2021

DNA sequencing by capillary electrophoresis with replaceable linear polyacrylamide and laser-induced fluorescence detection

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7 January 2021

Separation of transforming amino acid-substituting mutations in codons 12, 13 and 61 the N-ras gene by constant denaturant capillary electrophoresis (CDCE)

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7 January 2021

Mutational spectrometry without phenotypic selection: human mitochondrial DNA.

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7 January 2021

Detection of single-base mutations by a competitive mobility shift assay

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7 January 2021

Allele-specific PCR analysis of p53 codon 249 AGT transversion in liver tissues from patients with viral hepatitis

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7 January 2021

Quantitative or semi-quantitative PCR: reality versus myth

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7 January 2021

Quantitative analysis in molecular diagnostics

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

The application of quantitative polymerase chain reaction to therapeutic monitoring

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Direct measurement of mutational spectra in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

DNA polymerase fidelity and the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

The fidelity of Taq polymerase catalyzing PCR is improved by an N-terminal deletion

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Analysis of mutations using PCR and denaturing gradient gel electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Predominant mutations induced by the Thermococcus litoralis, vent DNA polymerase during DNA amplification in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

A rapid PCR fidelity assay

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Mutation detection with MutH, MutL, and MutS mismatch repair proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Phosphorothioate primers improve the amplification of DNA sequences by DNA polymerases with proofreading activity

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

High fidelity DNA synthesis by the Thermus aquaticus DNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Polymerase chain reaction strategy

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Effects of the T4 bacteriophage gene 32 product on the efficiency and fidelity of DNA amplification using T4 DNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Formation of UV-photoadducts during DNA purification

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

The Escherichia coli MutS DNA mismatch binding protein specifically binds O(6)-methylguanine DNA lesions.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

Human MutSα Specifically Binds to DNA Containing Aminofluorene and Acetylaminofluorene Adducts

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900026-4

7 January 2021

10.1016/S1383-5742(97)00026-4

Identifiers

DOI

1 reference

6 October 2017

1 reference