Targeting signal transduction for disease therapy (Q41611829)

5 October 2017

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title

Targeting signal transduction for disease therapy (English)

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5 October 2017

Levitzki A

1

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5 October 2017

1 June 1997

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5 October 2017

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5 October 2017

14

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5 October 2017

2

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5 October 2017

83-89

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https://scigraph.springernature.com/pub.10.1007/bf02990952

5 October 2017

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cites work

Targeted expression of the E6 and E7 oncogenes of human papillomavirus type 16 in the epidermis of transgenic mice elicits generalized epidermal hyperplasia involving autocrine factors

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02990952

The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies

21 January 2018

1 reference

12 December 2020

Tyrphostins. 3. Structure-activity relationship studies of alpha-substituted benzylidenemalononitrile 5-S-aryltyrphostins

1 reference

12 December 2020

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors

1 reference

12 December 2020

Tamoxifen therapy in breast cancer control worldwide.

1 reference

12 December 2020

Tyrphostin AG 494 blocks Cdk2 activation

1 reference

12 December 2020

Tyrphostin-induced differentiation of mouse erythroleukemia cells

1 reference

12 December 2020

Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins

1 reference

12 December 2020

Ribozymes designed to inhibit transformation of NIH3T3 cells by the activated c-Ha-ras gene

1 reference

12 December 2020

VEGF-mediated tumour angiogenesis: a new target for cancer therapy

1 reference

12 December 2020

Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

1 reference

12 December 2020

Inhibition of Cdk2 activation by selected tyrphostins causes cell cycle arrest at late G1 and S phase

1 reference

12 December 2020

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

12 December 2020

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

12 December 2020

Tyrosine kinase inhibition: an approach to drug development

1 reference

12 December 2020

A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines

1 reference

12 December 2020

RETRACTED: 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity

1 reference

12 December 2020

In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence

1 reference

12 December 2020

Receptor blockade with monoclonal antibodies as anti-cancer therapy

1 reference

12 December 2020

Signal-transduction therapy. A novel approach to disease management

1 reference

12 December 2020

Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors

1 reference

12 December 2020

RETRACTED: Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class

1 reference

12 December 2020

Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

1 reference

12 December 2020

Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation

1 reference

12 December 2020

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

1 reference

12 December 2020

Ribozyme-mediated cleavage of the BCRABL oncogene transcript: in vitro cleavage of RNA and in vivo loss of P210 protein-kinase activity

1 reference

12 December 2020

Flk-1 as a target for tumor growth inhibition.

1 reference

12 December 2020

Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo

1 reference

12 December 2020

Tyrphostins suppress the growth of psoriatic keratinocytes

1 reference

12 December 2020

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

12 December 2020

Monoclonal antibody therapy of human cancer: Taking the HER2 protooncogene to the clinic

1 reference

12 December 2020

Inhibition of platelet-derived growth factor-induced mitogenesis and tyrosine kinase activity in cultured bone marrow fibroblasts by tyrphostins

1 reference

12 December 2020

Expression of transforming growth factor-alpha, epidermal growth factor and the epidermal growth factor receptor in adenocarcinoma of the prostate and benign prostatic hyperplasia.

1 reference

12 December 2020

Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia.

1 reference

12 December 2020

ras oncogenes in human cancer: a review

1 reference

12 December 2020

HER-2/neu oncogene amplification and expression in breast and ovarian cancers

1 reference

12 December 2020

Antisense oligonucleotide inhibition of PDGFR-beta receptor subunit expression directs suppression of intimal thickening

1 reference

12 December 2020

SRC as a target for anti-cancer drugs

1 reference

12 December 2020

Controlled delivery of a tyrphostin inhibits intimal hyperplasia in a rat carotid artery injury model

1 reference

12 December 2020

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

12 December 2020

Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors

1 reference

12 December 2020

Inhibition of cyclin-dependent kinases by purine analogues.

1 reference

12 December 2020

Residues crucial for Ras interaction with GDP-GTP exchangers

1 reference

12 December 2020

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

1 reference

12 December 2020

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

1 reference

12 December 2020

Tyrphostins. 5. Potent inhibitors of platelet-derived growth factor receptor tyrosine kinase: structure-activity relationships in quinoxalines, quinolines, and indole tyrphostins

1 reference

12 December 2020

Epidermal growth factor (EGF) promotes chemomigration of a human prostate tumor cell line, and EGF immunoreactive proteins are present at sites of metastasis in the stroma of lymph nodes and medullary bone

1 reference

12 December 2020

Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies

1 reference

12 December 2020

The pathogenesis of atherosclerosis: a perspective for the 1990s

1 reference

12 December 2020

Epidermal‐Growth‐Factor‐Dependent Activation of the Src‐Family Kinases

1 reference

12 December 2020

Signalling pathways as targets for anticancer drug development

1 reference

12 December 2020

A potent specific pure antiestrogen with clinical potential

1 reference

12 December 2020

Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases

1 reference

12 December 2020

The antiproliferative effects of tyrosine kinase inhibitors tyrphostins on a human squamous cell carcinoma in vitro and in nude mice

1 reference

12 December 2020

Enhancement of chemosensitivity by tyrphostin AG825 in high-p185(neu) expressing non-small cell lung cancer cells

1 reference

12 December 2020

Tyrphostin induced growth inhibition: correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia

1 reference

12 December 2020

Platelet-derived growth factor and autocrine mechanisms of oncogenic processes

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02990952

1 reference

PubMed ID

9330267

Dimensions Publication ID

5 October 2017

1024928046

0 references

Fatcat ID

release_kdsw5jpp3ffgvpsb7e6ehdy45q

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kdsw5jpp3ffgvpsb7e6ehdy45q

24 November 2022

mapped directly with Wikidata item

PubMed ID

9330267

1 reference

PubMed ID

9330267