Pharmacological blockade of CCR1 ameliorates murine arthritis and alters cytokine networks in vivo (Q41603563)

4 October 2017

Pharmacological blockade of CCR1 ameliorates murine arthritis and alters cytokine networks in vivo (English)

1 reference

4 October 2017

M Amat

1

1 reference

4 October 2017

C F Benjamim

2

1 reference

4 October 2017

L M Williams

3

1 reference

4 October 2017

N Prats

4

1 reference

4 October 2017

E Terricabras

5

1 reference

4 October 2017

J Beleta

6

1 reference

4 October 2017

S L Kunkel

7

1 reference

4 October 2017

N Godessart

8

1 reference

4 October 2017

language of work or name

English

0 references

publication date

3 October 2006

1 reference

British Journal of Pharmacology

4 October 2017

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4 October 2017

149

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4 October 2017

666-675

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4 October 2017

6

1 reference

Chemokine receptors: attractive targets for drug discovery

4 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Therapeutic targeting of CCR1 attenuates established chronic fungal asthma in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Amelioration of rat adjuvant-induced arthritis by Met-RANTES.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Chemokines and their receptors in rheumatoid arthritis: future targets?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Drug discovery and chemokine receptor antagonists: eppur si muove!

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

CCR1 antagonists for the treatment of autoimmune diseases

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Chemokine blockade and chronic inflammatory disease: proof of concept in patients with rheumatoid arthritis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Development and evaluation of pharmacological agents targeting chemokine receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Macrophage inflammatory protein-1

6 June 2018

1 reference

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New therapeutics that modulate chemokine networks

6 June 2018

1 reference

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Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia

6 June 2018

1 reference

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A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Chemokines in autoimmune disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Design, synthesis, and discovery of a novel CCR1 antagonist

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

International union of pharmacology. XXII. Nomenclature for chemokine receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic cardiac allograft rejection

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Lack of chemokine receptor CCR1 enhances Th1 responses and glomerular injury during nephrotoxic nephritis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Amino-terminally modified RANTES analogues demonstrate differential effects on RANTES receptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Interleukin-10 prevents early cytokine release in severe intraabdominal infection and sepsis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014657

Pivotal role of CCR1-positive leukocytes in bleomycin-induced lung fibrosis in mice

19 August 2018

1 reference

12 December 2020

Airway remodeling is absent in CCR1-/- mice during chronic fungal allergic airway disease

1 reference

12 December 2020

Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent

1 reference

12 December 2020

Molecular and cellular mediators of interleukin-1-dependent acute inflammatory arthritis

1 reference

12 December 2020

Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation

1 reference

12 December 2020

Preparation of specific polyclonal antibodies to a C-C chemokine receptor, CCR1, and determination of CCR1 expression on various types of leukocytes

1 reference

12 December 2020

The phosphodiesterase type 4 (PDE4) inhibitor CP-80,633 elevates plasma cyclic AMP levels and decreases tumor necrosis factor-alpha (TNFalpha) production in mice: effect of adrenalectomy

1 reference

12 December 2020

Effect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1 mice

1 reference

12 December 2020

The inhibitory effect of rolipram on TNF-alpha production in mouse blood ex vivo is dependent upon the release of corticosterone and adrenaline

1 reference

12 December 2020

Suppression of TNF-alpha expression, inhibition of Th1 activity, and amelioration of collagen-induced arthritis by rolipram

1 reference

12 December 2020

Association of the course of collagen-induced arthritis with distinct patterns of cytokine and chemokine messenger RNA expression

1 reference

12 December 2020

An essential role for CCL3 in the development of collagen antibody-induced arthritis

1 reference

12 December 2020

Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0706912

1 reference

4 October 2017

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4 October 2017

1 reference