The neuropsychopharmacological potential of neuroactive steroids (Q41599127)

4 October 2017

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title

The neuropsychopharmacological potential of neuroactive steroids (English)

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4 October 2017

Rupprecht R

1

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4 October 2017

1 May 1997

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Journal of Psychiatric Research

4 October 2017

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4 October 2017

31

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4 October 2017

3

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4 October 2017

297-314

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Neurosteroids: biosynthesis, metabolism and function of pregnenolone and dehydroepiandrosterone in the brain.

4 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Neurosteroid metabolism. 7 alpha-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Drug discrimination analysis of endogenous neuroactive steroids in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

A prospective study of dehydroepiandrosterone sulfate and cognitive function in an older population: the Rancho Bernardo Study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Effects of intravenous progesterone infusions on the epileptic discharge frequency in women with partial epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Neurosteroids: a new function in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABAA receptor function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABAA receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Dehydroepiandrosterone regulation of the hepatic glucocorticoid receptor in the Zucker rat. The obesity research program

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Characterization of the purified pituitary cytosolic NADPH:5 alpha-dihydroprogesterone 3 alpha-hydroxysteroid oxidoreductase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Pregnanolone emulsion. A preliminary pharmacokinetic and pharmacodynamic study of a new intravenous anaesthetic agent.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

The pharmacology of neurosteroidogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Anxiolytic activity of an endogenous adrenal steroid.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Regulation of progesterone receptor-mediated transcription by phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

The steroid and thyroid hormone receptor superfamily

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Modulation of memory processing by glutamic acid receptor agonists and antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Dehydroepiandrosterone and its sulfate enhance memory retention in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Chemical characterization of neuroendocrine targets for progesterone in the female rat brain and pituitary.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Anxiolytic metabolites of progesterone: correlation with mood and performance measures following oral progesterone administration to healthy female volunteers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Progesterone metabolites, effective at the GABAA receptor complex, attenuate pain sensitivity in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

GABA-dependent modulation of the Cl- ionophore by steroids in rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

CSF neuroactive steroids in affective disorders: pregnenolone, progesterone, and DBI.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Assessment of cognitive performance after progesterone administration in healthy male volunteers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Modulation of recombinant α6β2γ2 GABAA receptors by neuroactive steroids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Allopregnanolone acts as an inhibitory modulator on alpha1- and alpha6-containing GABA-A receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Primary structure and expression of a functional human glucocorticoid receptor cDNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Actions of steroid hormones- and growth factors on glial cells of the central and peripheral nervous system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Neurosteroids and GABAA receptor function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

gamma-Aminobutyric acidA receptor regulation by a chloride-dependent kinase and a sodium-dependent phosphatase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Dehydroepiandrosterone sulfate in a long-term care aged population

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Non-genomic and genomic effects of steroids on neural activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Serum dehydroepiandrosterone sulfate in Alzheimer's disease and in multi-infarct dementia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

The neurosteroid tetrahydroprogesterone attenuates the endocrine response to stress and exerts glucocorticoid-like effects on vasopressin gene transcription in the rat hypothalamus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Dopaminergic and Ligand-Independent Activation of Steroid Hormone Receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

5β-Pregnan-3β-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor-complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Neurosteroids act on recombinant human GABAA receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Synthesis, metabolism, and pharmacological activity of 3 alpha-hydroxy steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Implications for theories of anaesthesia of antagonism between anaesthetic and non-anaesthetic steroids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Anxiolytic effects of progesterone are sexually dimorphic

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Marked decrease of plasma neuroactive steroids during alcohol withdrawal.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Progesterone receptor-mediated effects of neuroactive steroids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Steroid receptor-mediated effects of neuroactive steroids: characterization of structure-activity relationship

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Autoradiographic localization of glucocorticosteroid and progesterone binding sites in the human post-mortem brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Reduced plasma dehydroepiandrosterone concentrations in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Progesterone co-administration in patients discontinuing long-term benzodiazepine therapy: effects on withdrawal severity and taper outcome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Effects of subunit types of the cloned GABAA receptor on the response to a neurosteroid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Progesterone enhances inhibitory responses of cerebellar Purkinje cells mediated by the GABAA receptor subtype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Neurosteroid pregnenolone induces sleep-EEG changes in man compatible with inverse agonistic GABAA-receptor modulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

The NMDA receptor antagonists, CPP and γ-l-glutamyl-l-aspartate, selectively block post-training improvement of performance in a Y-maze avoidance learning task

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Comparative behavioral characterization of the neuroactive steroids 3 alpha-OH,5 alpha-pregnan-20-one and 3 alpha-OH,5 beta-pregnan-20-one in rodents.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

Progesterone and the premenstrual syndrome: a double blind crossover trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

inferred from DOI database lookup

7 January 2021

based on heuristic

The role of corticotropin-releasing hormone in the pathogenesis of Cushing's disease, anorexia nervosa, alcoholism, affective disorders and dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Molecular biology of GABAA receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2896%2900060-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0022-3956(96)00060-X

1 reference

4 October 2017

1 reference

PubMed ID

9306288