Cryo-EM structures of tau filaments from Alzheimer's disease. (Q41597304)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28678775%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

title

Cryo-EM structures of tau filaments from Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28678775%20AND%20SRC:MED&resulttype=core&format=json

cryogenic electron microscopy

24 March 2020

main subject

Alzheimer's disease

0 references

0 references

author

Benjamin Falcon

2

1 reference

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24 March 2020

Sjors Scheres

10

1 reference

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24 March 2020

8

Bernardino Ghetti

1 reference

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24 March 2020

author name string

Anthony W P Fitzpatrick

1

1 reference

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24 March 2020

Shaoda He

3

1 reference

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24 March 2020

Garib Murshudov

5

1 reference

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24 March 2020

Holly J Garringer

6

1 reference

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24 March 2020

R Anthony Crowther

7

1 reference

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24 March 2020

Michel Goedert

9

1 reference

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24 March 2020

Alexey G Murzin

4

1 reference

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24 March 2020

language of work or name

English

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publication date

5 July 2017

1 reference

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24 March 2020

1 reference

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24 March 2020

volume

547

1 reference

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24 March 2020

page(s)

185-190

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24 March 2020

issue

7662

1 reference

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describes a project that uses

24 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5552202/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nature23002

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cites work

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Structure-based drug design identifies polythiophenes as antiprion compounds

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Identification of key amino acids responsible for the distinct aggregation properties of microtubule-associated protein 2 and tau.

6 June 2018

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Folding of the Tau Protein on Microtubules

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Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

6 June 2018

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Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer's disease brain.

6 June 2018

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6 June 2018

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6 June 2018

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Brain homogenates from human tauopathies induce tau inclusions in mouse brain

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila

6 June 2018

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6 June 2018

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7 January 2021

Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure

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Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

6 June 2018

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The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

6 June 2018

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Reappraisal of the fine structure of Alzheimer's neurofibrillary tangles.

6 June 2018

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Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

6 June 2018

1 reference

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

6 June 2018

1 reference

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Structural characterization of the core of the paired helical filament of Alzheimer disease

6 June 2018

1 reference

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Identification of 3- and 4-repeat tau isoforms within the PHF in Alzheimer's disease

6 June 2018

1 reference

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Straight and paired helical filaments in Alzheimer disease have a common structural unit

6 June 2018

1 reference

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Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

6 June 2018

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Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo.

6 June 2018

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Conformation determines the seeding potencies of native and recombinant Tau aggregates

19 August 2018

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THE FINE STRUCTURE OF NEUROFIBRILLARY TANGLES IN ALZHEIMER'S DISEASE.

19 August 2018

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Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

19 August 2018

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An R5L tau mutation in a subject with a progressive supranuclear palsy phenotype.

19 August 2018

1 reference

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Late-onset frontotemporal dementia with a novel exon 1 (Arg5His) tau gene mutation

19 August 2018

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Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau.

19 August 2018

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19 August 2018

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Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure

19 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23002

7 January 2021

Structure of Polyglycine II

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23002

7 January 2021

The dynamic structure of filamentous tau

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23002

7 January 2021

Domains of tau protein and interactions with microtubules

1 reference

https://api.crossref.org/works/10.1038%2FNATURE23002

7 January 2021

Identifiers

DOI

10.1038/NATURE23002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28678775%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28678775%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference