Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers (Q41575754)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28737909%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

title

Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers (English)

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25 March 2020

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4

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25 March 2020

Joanne Edwards

6

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25 March 2020

Sabin Llona-Minguez

14

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Andrew Paul

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Robin Plevin

18

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Murray N Robertson

19

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Oliver B Sutcliffe

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Simon P Mackay

24

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25 March 2020

author name string

Nahoum G Anthony

1

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25 March 2020

Jessica Baiget

2

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25 March 2020

Giacomo Berretta

3

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25 March 2020

David Breen

5

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25 March 2020

Carly Gamble

7

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25 March 2020

Alexander I Gray

8

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25 March 2020

Alan L Harvey

9

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Sophia Hatziieremia

10

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25 March 2020

Ka Ho Ho

11

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25 March 2020

Judith K Huggan

12

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Stuart Lang

13

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25 March 2020

Jia Lin Luo

15

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Kathryn McIntosh

16

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25 March 2020

Rebecca Scott

20

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25 March 2020

Colin J Suckling

21

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Louise C Young

23

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language of work or name

English

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publication date

15 August 2017

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Journal of Medicinal Chemistry

25 March 2020

published in

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volume

60

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25 March 2020

issue

16

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25 March 2020

page(s)

7043-7066

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IKKα inibition by a glucosamine derivative enhances Maspin expression in osteosarcoma cell line

25 March 2020

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Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.

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Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin

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IkappaB kinase inhibitors for treating autoimmune and inflammatory disorders: potential and challenges

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6 June 2018

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Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation

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6 June 2018

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6 June 2018

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6 June 2018

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Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokin

19 August 2018

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19 August 2018

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19 August 2018

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Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

19 August 2018

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Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation

19 August 2018

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Activation of NF-κB via the IκB Kinase Complex Is Both Essential and Sufficient for Proinflammatory Gene Expression in Primary Endothelial Cells

19 August 2018

1 reference

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PTP1B inhibitor Ertiprotafib is also a potent inhibitor of IkappaB kinase beta (IKK-beta)

2 December 2018

1 reference

12 December 2020

Simple Methods for Preparing Recombinant Adenoviruses for High-Efficiency Transduction of Vascular Cells

1 reference

12 December 2020

IKKalpha and IKKbeta function in TNFalpha-stimulated adhesion molecule expression in human aortic smooth muscle cells

1 reference

12 December 2020

Artemisolide is a typical inhibitor of IkappaB kinase beta targeting cysteine-179 residue and down-regulates NF-kappaB-dependent TNF-alpha expression in LPS-activated macrophages

1 reference

12 December 2020

10.1021/ACS.JMEDCHEM.7B00484

Identifiers

DOI

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25 March 2020

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25 March 2020

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