Treatment with Dexamethasone and Monophosphoryl Lipid A Removes Disease-Associated Transcriptional Signatures in Monocyte-Derived Dendritic Cells from Rheumatoid Arthritis Patients and Confers Tolerogenic Features. (Q41563600)

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scientific article published on 25 October 2016

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English	Treatment with Dexamethasone and Monophosphoryl Lipid A Removes Disease-Associated Transcriptional Signatures in Monocyte-Derived Dendritic Cells from Rheumatoid Arthritis Patients and Confers Tolerogenic Features.	scientific article published on 25 October 2016

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scholarly article

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27 March 2020

Treatment with Dexamethasone and Monophosphoryl Lipid A Removes Disease-Associated Transcriptional Signatures in Monocyte-Derived Dendritic Cells from Rheumatoid Arthritis Patients and Confers Tolerogenic Features (English)

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27 March 2020

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rheumatoid arthritis

1 reference

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Rodrigo A Morales

6

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Catharien M. Hilkens

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author name string

Paulina A García-González

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Katina Schinnerling

2

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Alejandro Sepúlveda-Gutiérrez

3

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Jaxaira Maggi

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Lorena Hoyos

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Ahmed M Mehdi

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Hendrik J Nel

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Lilian Soto

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Bárbara Pesce

10

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María Carmen Molina

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Miguel Cuchacovich

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27 March 2020

Milton L Larrondo

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Óscar Neira

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27 March 2020

Diego Francisco Catalán

15

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27 March 2020

Ricardo A Verdugo

18

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27 March 2020

Juan C Aguillón

19

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publication date

25 October 2016

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27 March 2020

Frontiers in Immunology

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27 March 2020

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27 March 2020

458

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27 March 2020

Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4+ T Cells

1 reference

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6 June 2018

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

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Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis

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6 June 2018

DC-SCRIPT Regulates IL-10 Production in Human Dendritic Cells by Modulating NF-κBp65 Activation.

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6 June 2018

Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3(NLRP3)-inflammasome activation:

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Crossreactivity to vinculin and microbes provides a molecular basis for HLA-based protection against rheumatoid arthritis

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Skewing dendritic cell differentiation towards a tolerogenic state for recovery of tolerance in rheumatoid arthritis.

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Tolerogenic dendritic cells derived from donors with natural rubber latex allergy modulate allergen-specific T-cell responses and IgE production

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Induction of Th17 lymphocytes and Treg cells by monocyte-derived dendritic cells in patients with rheumatoid arthritis and systemic lupus erythematosus

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A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines.

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Biologic therapy in rheumatoid arthritis

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T cell killing by tolerogenic dendritic cells protects mice from allergy

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CCL18 differentiates dendritic cells in tolerogenic cells able to prime regulatory T cells in healthy subjects

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Putting endotoxin to work for us: monophosphoryl lipid A as a safe and effective vaccine adjuvant

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19 August 2018

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21 January 2018

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21 January 2018

Physiological concentrations of transforming growth factor beta1 selectively inhibit human dendritic cell function

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Th17/Treg imbalance and cytokine environment in peripheral blood of patients with rheumatoid arthritis

1 reference

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12 December 2020

based on heuristic

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Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/27826300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells (DCs) in rheumatoid arthritis (RA): progenitor cells and soluble factors contained in RA synovial fluid yield a subset of myeloid DCs that preferentially activate Th1 inflammatory-type responses

1 reference

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12 December 2020

based on heuristic

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CARD11 blockade suppresses murine collagen-induced arthritis via inhibiting CARD11/Bcl10 assembly and T helper type 17 response

1 reference

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12 December 2020

based on heuristic

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Monophosphoryl lipid A activates both human dendritic cells and T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27826300

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FIMMU.2016.00458

1 reference

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27 March 2020

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27 March 2020

1 reference

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27 March 2020

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