Mannose binding lectin 2 (Q415443)

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mammalian protein found in Homo sapiens

Mannose-binding lectin
Mannan-binding protein
mannan-binding lectin
mannose-binding lectin (protein C) 2, soluble (opsonic defect)
mannose-binding lectin 2, soluble (opsonic defect)
mannose-binding protein C
collectin-1
MBL2
MBP1
mannose-binding lectin
MBL

Language	Label	Description	Also known as
English	Mannose binding lectin 2	mammalian protein found in Homo sapiens	Mannose-binding lectin Mannan-binding protein mannan-binding lectin mannose-binding lectin (protein C) 2, soluble (opsonic defect) mannose-binding lectin 2, soluble (opsonic defect) mannose-binding protein C collectin-1 MBL2 MBP1 mannose-binding lectin MBL

Statements

1 reference

13 November 2019

UniProt protein ID

mannose-binding lectins

0 references

C-type lectin-like/link domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11226

C-type lectin fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11226

Mannose-binding protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11226

Collectin, C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

C-type lectin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

collagen triple helix repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

calcium ion binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

calcium-dependent protein binding

determination method

protein binding

determination method

3 references

8 April 2019

MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Structural insights into the initiating complex of the lectin pathway of complement activation.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

CD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding site

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

mannose binding

determination method

5 references

16 July 2018

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

Endothelial oxidative stress activates the lectin complement pathway: role of cytokeratin 1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

signaling receptor binding

determination method

1 reference

8 April 2019

Endothelial oxidative stress activates the lectin complement pathway: role of cytokeratin 1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

carbohydrate binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

serine-type endopeptidase activity

determination method

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

mannose binding

determination method

6 references

8 April 2019

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Endothelial oxidative stress activates the lectin complement pathway: role of cytokeratin 1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

determination method

1 reference

8 April 2019

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

extracellular space

determination method

3 references

16 July 2018

High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

extracellular space

determination method

4 references

8 April 2019

High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

extracellular matrix

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

collagen-containing extracellular matrix

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

biological process

complement activation, lectin pathway

determination method

6 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

Endothelial oxidative stress activates the lectin complement pathway: role of cytokeratin 1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

16 July 2018

Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

positive regulation of phagocytosis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

killing by host of symbiont cells

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

negative regulation of viral process

determination method

1 reference

8 April 2019

Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

immune system process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

complement activation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

response to oxidative stress

determination method

1 reference

8 April 2019

Endothelial oxidative stress activates the lectin complement pathway: role of cytokeratin 1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

acute-phase response

determination method

1 reference

8 April 2019

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

defense response to bacterium

determination method

1 reference

8 April 2019

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

complement activation, classical pathway

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

determination method

1 reference

8 April 2019

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

determination method

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11226&geneProductId=UniProtKB:P11226

determination method

complement activation, lectin pathway

determination method

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Endothelial oxidative stress activates the lectin complement pathway: role of cytokeratin 1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

growth plate cartilage chondrocyte morphogenesis

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11226

determination method

Gene Atlas image

PBB GE MBL2 207256 at fs.png
732 × 530; 11 KB

0 references

http://purl.uniprot.org/uniprot/P11226

1 reference

Identifiers.org

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

7 March 2020

1 reference

7 March 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000363079

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000363079

1 reference

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(15 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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