Evidence for similar conformational changes in α2-macroglobulin on reaction with primary amines or proteolytic enzymes (Q41542489)

2 October 2017

Evidence for similar conformational changes in alpha 2-macroglobulin on reaction with primary amines or proteolytic enzymes (English)

1 reference

PMCID

1153867

2 October 2017

Evidence for similar conformational changes in α2-macroglobulin on reaction with primary amines or proteolytic enzymes (English)

1 reference

23 August 2023

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6186243

23 August 2023

1 reference

23 August 2023

1 reference

23 August 2023

author name string

I. Björk

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6186243

23 August 2023

W. W. Fish

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6186243

23 August 2023

language of work or name

English

0 references

publication date

1 November 1982

1 reference

PMCID

1153867

full work available at URL

2 October 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/6186243/pdf/?tool=EBI

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6186243

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/6186243/?tool=EBI

23 August 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6186243

https://europepmc.org/articles/PMC1153867

23 August 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6186243

https://europepmc.org/articles/PMC1153867?pdf=render

23 August 2023

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6186243

https://portlandpress.com/biochemj/article-pdf/207/2/347/577729/bj2070347.pdf

23 August 2023

file format

Portable Document Format

1 reference

23 August 2023

1 reference

2 October 2017

207

1 reference

2 October 2017

2

1 reference

2 October 2017

347-356

1 reference

TRYPSINOGEN AND CHYMOTRYPSINOGEN AS HOMOLOGOUS PROTEINS

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Further characterization of the covalent linking reaction of α2-macroglobulin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Clearance and binding of two electrophoretic "fast" forms of human alpha 2-macroglobulin.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Recognition of nucleophile-treated alpha 2-macroglobulin by the alveolar macrophage alpha-macroglobulin . protease complex receptor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Reactive site in human alpha 2-macroglobulin: circumstantial evidence for a thiolester

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Amino acid sequence of the tryptic peptide containing the alkylamine-reactive site from human alpha 2-macroglobulin. Identification of gamma-glutamylmethylamide

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Corrections to the amino acid sequence of bovine chymotrypsinogen A.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Thiol reduction of human α2-macroglobulin. The subunit structure

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Immunochemical quantitation of antigens by single radial immunodiffusion

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

21 Ultraviolet difference spectroscopy—new techniques and applications

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Studies on human plasma alpha 2-macroglobulin-enzyme interactions. Evidence for proteolytic modification of the subunit chain structure

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Differential sedimentation coefficients. I. Precise measurement. Determination of concentration dependence for IgG-immunoglobulin.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

The production of an inactive form of antithrombin through limited proteolysis by thrombin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Resolution of α and β anhydrotrypsin by affinity chromatography

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Purification of human plasma α2 macroglobulin and α1 proteinase inhibitor using zinc chelate chromatography

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Characterization of alkylamine-sensitive site in alpha 2-macroglobulin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin molecule

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Analysis of macrophage surface receptors. II. Internalization of alpha-macroglobulin . trypsin complexes by rabbit alveolar macrophages

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Analysis of macrophage surface receptors. I. Binding of alpha-macroglobulin . protease complexes to rabbit alveolar macrophages

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Structural characterization of human alpha2-macroglobulin subunits

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Rotational relaxation of free and protease-bound alpha2-macroglobulin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Physical and chemical properties of human plasma β2-macroglobulin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Stability and subunit structure of human alpha2-macroglobulin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Human alpha2-macroglobulin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

The molecular size and shape of the pancreatic proteases. III. alpha-Chymotrypsin.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

Covalent binding of proteinases in their reaction with α2-macroglobulin

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1153867

The alpha 2-macroglobulin of human plasma. I. Isolation and composition

19 August 2018

1 reference

12 December 2020

The combining ratio between trypsin and serum alpha-2-macroglobulin

1 reference

12 December 2020

Molecular alteration of alpha-2-macroglobulin by aliphatic amines

1 reference

12 December 2020

Computed circular dichroism spectra for the evaluation of protein conformation

1 reference

12 December 2020

Isolation of trypsins by affinity chromatography

1 reference

12 December 2020

Uptake of proteinase-α-macroglobulin complexes by macrophages☆

1 reference

12 December 2020

Decreased binding of heparin to antithrombin following the interaction between antithrombin and thrombin

1 reference

12 December 2020

A thiol-ester in α2-macroglobulin cleaved during proteinase complex formation

1 reference

12 December 2020

Sequence location of the reactive thiol ester in human alpha 2-macroglobulin

1 reference

12 December 2020

Primary structure of the 'bait' region for proteinases in alpha 2-macroglobulin. Nature of the complex

1 reference

12 December 2020

Trypsin-induced activation of the thiol esters in α2-macroglobulin generates a short-lived intermediate (‘nascent’ α2M) that can react rapidly to incorporate not only methylamine or putrescine but also proteins lacking proteinase activity

1 reference

12 December 2020

Inhibition of proteases by alpha 2-macroglobulin. The role of lysyl amino groups of trypsin in covalent complex formation

1 reference

12 December 2020

The optical properties of α2-macroglobulin from normal and from cystic fibrosis plasma

1 reference

12 December 2020

Alpha 2-macroglobulin-protease reactions: relationship of covalent bond formation, methylamine reactivity, and specific proteolysis

1 reference

12 December 2020

Molecular-kinetic properties of crystalline trypsinogen

1 reference

12 December 2020

THE SPECTROPHOTOMETRIC TITRATION OF THE SULFHYDRYL AND PHENOLIC GROUPS OF ALDOLASE

1 reference

12 December 2020

Amino-Acid Sequence of Bovine Chymotrypsinogen-A

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2070347

1 reference

2 October 2017

1 reference

2 October 2017

1 reference

PMCID

1153867