Examining BCL-2 family function with large unilamellar vesicles (Q41460863)

1 October 2017

Examining BCL-2 family function with large unilamellar vesicles (English)

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1 October 2017

3

1 reference

1 October 2017

Thibaud T Renault

2

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author name string

James J Asciolla

series ordinal

1

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1 October 2017

5 October 2012

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Journal of Visualized Experiments

1 October 2017

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1 October 2017

68

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BH3-triggered structural reorganization drives the activation of proapoptotic BAX.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

BH3 domains other than Bim and Bid can directly activate Bax/Bak

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

11 June 2018

The BCL-2 family reunion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

BAX activation is initiated at a novel interaction site

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

Apoptotic pathways: ten minutes to dead

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

Structure of Bax: coregulation of dimer formation and intracellular localization

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3490295

Nonionic detergents induce dimerization among members of the Bcl-2 family

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23070252

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3791/4291

1 reference

1 October 2017

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1 October 2017

1 reference

PMCID

3490295