Heat shock response associated with hepatocarcinogenesis in a murine model of hereditary tyrosinemia type I. (Q41457848)

30 September 2017

Heat shock response associated with hepatocarcinogenesis in a murine model of hereditary tyrosinemia type I. (English)

1 reference

30 September 2017

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1

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30 September 2017

5

Robert M Tanguay

1 reference

30 September 2017

Geneviève Morrow

2

1 reference

PMCID

4074813

30 September 2017

Vincent Roy

series ordinal

3

1 reference

PMCID

4074813

30 September 2017

Diana Orejuela

series ordinal

4

1 reference

30 September 2017

23 April 2014

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30 September 2017

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30 September 2017

6

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30 September 2017

998-1019

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30 September 2017

2

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Creative Commons Attribution 4.0 International

30 September 2017

start time

23 April 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4074813/fullTextXML

inferred from PubMed Central ID database lookup

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Bcl-2-enhanced efficacy of microtubule-targeting chemotherapy through Bim overexpression: implications for cancer treatment

30 September 2017

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30 September 2017

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Translocation of HSP27 into liver cancer cell nucleus may be associated with phosphorylation and O-GlcNAc glycosylation

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.

30 September 2017

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Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma

30 September 2017

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Resistance to paclitaxel therapy is related with Bcl-2 expression through an estrogen receptor mediated pathway in breast cancer.

30 September 2017

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30 September 2017

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Phosphorylated heat shock protein 27 represses growth of hepatocellular carcinoma via inhibition of extracellular signal-regulated kinase

30 September 2017

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The HspA2 protein localizes in nucleoli and centrosomes of heat shocked cancer cells.

30 September 2017

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Heat shock proteins: essential proteins for apoptosis regulation

30 September 2017

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The expression of HSP27 is associated with poor clinical outcome in intrahepatic cholangiocarcinoma

30 September 2017

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Phosphorylation of Ser78 of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer

30 September 2017

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Recruitment of phosphorylated small heat shock protein Hsp27 to nuclear speckles without stress

30 September 2017

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Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties

30 September 2017

1 reference

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Effect of methylglyoxal modification and phosphorylation on the chaperone and anti-apoptotic properties of heat shock protein 27.

30 September 2017

1 reference

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Involvement of endoplasmic reticulum stress in hereditary tyrosinemia type I.

30 September 2017

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Apoptotic pathways and therapy resistance in human malignancies

30 September 2017

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Correlation between clinicopathology and expression of heat shock protein 70 and glucose-regulated protein 94 in human colonic adenocarcinoma

30 September 2017

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Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms

30 September 2017

1 reference

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The Bcl-2 protein family and its role in the development of neoplastic disease

30 September 2017

1 reference

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"The stress of dying": the role of heat shock proteins in the regulation of apoptosis

30 September 2017

1 reference

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Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy: a comprehensive review

30 September 2017

1 reference

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Differential, stage-dependent expression of Hsp70, Hsp110 and Bcl-2 in colorectal cancer

30 September 2017

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JPDI, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs

30 September 2017

1 reference

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ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress

30 September 2017

1 reference

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The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C.

30 September 2017

1 reference

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Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

30 September 2017

1 reference

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Fumarylacetoacetate, the metabolite accumulating in hereditary tyrosinemia, activates the ERK pathway and induces mitotic abnormalities and genomic instability

30 September 2017

1 reference

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Heat shock proteins: endogenous modulators of apoptotic cell death

30 September 2017

1 reference

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Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors

30 September 2017

1 reference

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Differential regulation of HSP27 oligomerization in tumor cells grown in vitro and in vivo

30 September 2017

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Mitochondria: execution central

30 September 2017

1 reference

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Inhibition of Daxx-mediated apoptosis by heat shock protein 27

30 September 2017

1 reference

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Hsp27 negatively regulates cell death by interacting with cytochrome c.

30 September 2017

1 reference

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Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis

30 September 2017

1 reference

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Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Hepatocyte injury in tyrosinemia type 1 is induced by fumarylacetoacetate and is inhibited by caspase inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Complete rescue of lethal albino c14CoS mice by null mutation of 4-hydroxyphenylpyruvate dioxygenase and induction of apoptosis of hepatocytes in these mice by in vivo retrieval of the tyrosine catabolic pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

The mutagenicity of the tyrosine metabolite, fumarylacetoacetate, is enhanced by glutathione depletion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27.

30 September 2017

1 reference

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Tyrosine and its catabolites: from disease to cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Assay of fumarylacetoacetate fumarylhydrolase in human liver-deficient activity in a case of hereditary tyrosinemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Different molecular basis for fumarylacetoacetate hydrolase deficiency in the two clinical forms of hereditary tyrosinemia (type I)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Tyrosinaemia type I — an update

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Type 1 hereditary tyrosinemia. Evidence for molecular heterogeneity and identification of a causal mutation in a French Canadian patient

30 September 2017

1 reference

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On the enzymic defects in hereditary tyrosinemia

30 September 2017

1 reference

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The occurrence of hepatoma in the chronic form of hereditary tyrosinemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Immunohistochemical detection of bcl-2 protein in normal and pathological human liver.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Prognostic significance of heat shock proteins in urothelial carcinoma of the urinary bladder

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Altered expression of cellular Bcl-2 in the progression of hamster cholangiocarcinogenesis.

19 August 2018

1 reference

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Role of heat-shock protein (HSP) 70-2 genotype in peptic ulcer in Japanese population.

19 August 2018

1 reference

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Neurocognitive outcome in patients with hypertyrosinemia type I after long-term treatment with NTBC.

19 August 2018

1 reference

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Heat-shock protein 70-2 (HSP70-2) expression in bladder urothelial carcinoma is associated with tumour progression and promotes migration and invasion.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Hepatic stress in hereditary tyrosinemia type 1 (HT1) activates the AKT survival pathway in the fah-/- knockout mice model

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Attenuated phosphorylation of heat shock protein 27 correlates with tumor progression in patients with hepatocellular carcinoma

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

HSP70 deficiency results in activation of c-Jun N-terminal Kinase, extracellular signal-regulated kinase, and caspase-3 in hyperosmolarity-induced apoptosis

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Extensive changes in liver gene expression induced by hereditary tyrosinemia type I are not normalized by treatment with 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC).

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Long-term therapy with NTBC and tyrosine-restricted diet in a murine model of hereditary tyrosinemia type I.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Cyclin B-dependent kinase and caspase-1 activation precedes mitochondrial dysfunction in fumarylacetoacetate-induced apoptosis.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

E mu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Hereditary tyrosinemia type I: a new clinical classification with difference in prognosis on dietary treatment.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074813

Hepatocellular carcinoma despite long-term survival in chronic tyrosinaemia I

19 August 2018

1 reference

12 December 2020

Neurologic crises in hereditary tyrosinemia

1 reference

12 December 2020

Hepatocellular carcinoma in hereditary tyrosinemia type I despite 2-(2 nitro-4-3 trifluoro- methylbenzoyl)-1, 3-cyclohexanedione treatment

1 reference

12 December 2020

Heterogeneity of follow-up procedures in French and Belgian patients with treated hereditary tyrosinemia type 1: results of a questionnaire and proposed guidelines

1 reference

12 December 2020

Tissue-specific expression of heat shock proteins of the mouse in the absence of stress

1 reference

12 December 2020

Heat shock proteins 27, 60 and 70 as prognostic markers of prostate cancer

1 reference

12 December 2020

[Heat shock proteins as molecular chaperones]

1 reference

12 December 2020

Increased expression of the M(r) 27,000 heat shock protein (hsp27) in in vitro differentiated normal human keratinocytes

1 reference

12 December 2020

Expression of Bcl-2 protein in human primary breast carcinomas and its correlation with multifocality, histopathological types and prognosis

1 reference

12 December 2020

Expression of heat shock protein 70 (HSP70) in patients with colorectal adenocarcinoma--immunohistochemistry and Western blot analysis

1 reference

12 December 2020

Identifiers

DOI

10.3390/CANCERS6020998

1 reference

30 September 2017

1 reference

30 September 2017

1 reference

PMCID

4074813