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Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase (Q41437655)

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scientific article published on October 1994

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English	Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase	scientific article published on October 1994

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29 October 2019

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase (English)

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29 October 2019

1

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29 October 2019

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E J Foulstone

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29 October 2019

S W Young

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29 October 2019

J M Tavaré

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29 October 2019

C G Proud

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29 October 2019

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1 October 1994

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29 October 2019

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Biochemical Journal

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29 October 2019

303 ( Pt 1)

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29 October 2019

15-20

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29 October 2019

Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

1 reference

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1 October 2017

Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy

1 reference

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1 October 2017

The insulin signaling system

1 reference

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1 October 2017

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 reference

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The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras.

1 reference

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1 October 2017

Identification of novel phosphorylation sites in the beta-subunit of translation initiation factor eIF-2

1 reference

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1 October 2017

Activation of Raf as a result of recruitment to the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

1 October 2017

Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase

1 reference

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1 October 2017

Molecular cloning and expression of glycogen synthase kinase-3/factor A

1 reference

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1 October 2017

Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6.

1 reference

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1 October 2017

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

1 reference

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1 October 2017

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

1 October 2017

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

1 reference

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1 October 2017

A common denominator linking glycogen metabolism, nuclear oncogenes and development

1 reference

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1 October 2017

Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

1 October 2017

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

1 October 2017

Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin

1 reference

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1 October 2017

Glycogen synthase kinase-3: functions in oncogenesis and development

1 reference

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1 October 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

1 October 2017

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Differential Raf requirement for activation of mitogen-activated protein kinase by growth factors, phorbol esters, and calcium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Purification and characterisation of the insulin-stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Involvement of p21ras in activation of extracellular signal-regulated kinase 2.

1 reference

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11 June 2018

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Identification of multifunctional ATP-citrate lyase kinase as the alpha-isoform of glycogen synthase kinase-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Characterization of insulin-stimulated protein serine/threonine kinases in CHO cells expressing human insulin receptors with point and deletion mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

11 June 2018

Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

19 August 2018

ATP x Mg-dependent protein phosphatase from rabbit skeletal muscle. II. Purification of the activating factor and its characterization as a bifunctional protein also displaying synthase kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of Glycogen Synthase Kinase 3 from Rabbit Skeletal Muscle.. Copurification with the Activating Factor (FA)of the (Mg-ATP) Dependent Protein Phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycogen synthase from rabbit skeletal muscle; effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathway to signal achievement

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3030015

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7945234%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7945234%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7945234%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

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