Low affinity binding site clusters confer hox specificity and regulatory robustness. (Q41392070)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557079%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Low affinity binding site clusters confer hox specificity and regulatory robustness (English)

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26 February 2020

4

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26 February 2020

author name string

Justin Crocker

1

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26 February 2020

Namiko Abe

2

1 reference

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26 February 2020

Lucrezia Rinaldi

3

1 reference

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26 February 2020

Nicolás Frankel

5

1 reference

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26 February 2020

Shu Wang

6

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26 February 2020

Ahmad Alsawadi

7

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26 February 2020

Philippe Valenti

8

1 reference

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26 February 2020

Serge Plaza

9

1 reference

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26 February 2020

François Payre

10

1 reference

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26 February 2020

Richard S Mann

11

1 reference

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26 February 2020

David L Stern

12

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26 February 2020

language of work or name

English

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publication date

31 December 2014

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26 February 2020

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26 February 2020

volume

160

1 reference

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26 February 2020

issue

1-2

1 reference

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26 February 2020

page(s)

191-203

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describes a project that uses

26 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4449256/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Phenotypic robustness conferred by apparently redundant transcriptional enhancers

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Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

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Structural rules and complex regulatory circuitry constrain expression of a Notch- and EGFR-regulated eye enhancer

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Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputs

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Hox specificity unique roles for cofactors and collaborators

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Evolution acts on enhancer organization to fine-tune gradient threshold readouts

1 October 2017

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Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites

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Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences

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Functional Specificity of a Hox Protein Mediated by the Recognition of Minor Groove Structure

1 October 2017

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Shavenbaby couples patterning to epidermal cell shape control

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Hox cofactors in vertebrate development

1 October 2017

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Cloning of the homeotic Sex combs reduced gene in Drosophila and in situ localization of its transcripts

1 October 2017

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Bicoid cooperative DNA binding is critical for embryonic patterning in Drosophila

1 October 2017

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1 October 2017

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Direct regulation of knot gene expression by Ultrabithorax and the evolution of cis-regulatory elements in Drosophila

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1 October 2017

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1 October 2017

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NF-kappaB signaling pathways in mammalian and insect innate immunity

1 October 2017

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The control of trunk Hox specificity and activity by Extradenticle

1 October 2017

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The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, extradenticle, and suppresses eye development in Drosophila

1 October 2017

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1 October 2017

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Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

1 October 2017

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Genes controlling segmental specification in the Drosophila thorax

1 October 2017

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Analysis of larval segmentation in lethal genotypes associated with the antennapedia gene complex in Drosophila melanogaster

1 October 2017

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Hox and HOM: homologous gene clusters in insects and vertebrates

1 October 2017

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Regulation of a Segmentation Stripe by Overlapping Activators and Repressors in the Drosophila Embryo

1 October 2017

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Homeobox genes and axial patterning

1 October 2017

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A gene complex controlling segmentation in Drosophila

1 October 2017

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Low-affinity transcription factor binding sites shape morphogen responses and enhancer evolution

1 October 2017

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Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins

11 June 2018

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Establishment of medial fates along the proximodistal axis of the Drosophila leg through direct activation of dachshund by Distalless

11 June 2018

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Molecular integration of wingless, decapentaplegic, and autoregulatory inputs into Distalless during Drosophila leg development.

11 June 2018

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11 June 2018

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11 June 2018

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The control of the yeast H2O2 response by the Msn2/4 transcription factors.

11 June 2018

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The hardwiring of development: organization and function of genomic regulatory systems.

11 June 2018

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Genetic organization of Drosophila bithorax complex.

11 June 2018

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The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo.

11 June 2018

1 reference

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Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen.

11 June 2018

1 reference

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Functional dissection of Ultrabithorax proteins in D. melanogaster.

11 June 2018

1 reference

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abdA expression in Drosophila embryos

11 June 2018

1 reference

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Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity

11 June 2018

1 reference

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Predicting expression patterns from regulatory sequence in Drosophila segmentation.

11 June 2018

1 reference

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Common functions of central and posterior Hox genes for the repression of head in the trunk of Drosophila.

19 August 2018

1 reference

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Morphological evolution through multiple cis-regulatory mutations at a single gene.

19 August 2018

1 reference

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The Ovo/Shavenbaby transcription factor specifies actin remodelling during epidermal differentiation in Drosophila.

19 August 2018

1 reference

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Direct and concentration-dependent regulation of the proneural gene Neurogenin2 by Pax6.

19 August 2018

1 reference

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Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex.

19 August 2018

1 reference

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ovo/svb integrates Wingless and DER pathways to control epidermis differentiation

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449256

Nuclear translocation of extradenticle requires homothorax, which encodes an extradenticle-related homeodomain protein

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449256

Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

19 August 2018

1 reference

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The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.

19 August 2018

1 reference

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The gradient morphogen bicoid is a concentration-dependent transcriptional activator.

19 August 2018

1 reference

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The developmental effect of overexpressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449256

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster : II. Zygotic loci on the third chromosome

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25557079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2014.11.041

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557079%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557079%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

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