Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man. (Q41334106)

29 September 2017

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title

Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man. (English)

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29 September 2017

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M Gerlach

1

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PubMed ID

9013391

29 September 2017

P Riederer

series ordinal

2

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29 September 2017

1 January 1996

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Journal of Neural Transmission

29 September 2017

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29 September 2017

103

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29 September 2017

987-1041

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29 September 2017

8-9

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https://scigraph.springernature.com/pub.10.1007/bf01291788

29 September 2017

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12 December 2020

The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons.

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12 December 2020

Free radical-generated neurotoxicity of 6-hydroxydopamine

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12 December 2020

Lesions of Central Norepinephrine Terminals with 6-OH-Dopamine: Biochemistry and Fine Structure

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12 December 2020

Enzymatic oxidation of the dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, into 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion

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12 December 2020

MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease

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12 December 2020

Apoptosis and necrosis. Basic types and mechanisms of cell death

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12 December 2020

MRI, brain iron and experimental Parkinson's disease

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12 December 2020

Neurochemical and functional consequences following 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) and methamphetamine.

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12 December 2020

3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists

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12 December 2020

Competitive and noncompetitive N-methyl-D-aspartate antagonists protect dopaminergic and serotonergic neurotoxicity produced by methamphetamine in various brain regions

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12 December 2020

Effects of nimodipine on the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced depletions in the biogenic amine levels in mice.

1 reference

12 December 2020

Predicting Parkinson's disease

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12 December 2020

Nigral and extranigral pathology in Parkinson's disease.

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12 December 2020

A novel reaction time task for investigating force and time parameters of locomotor initiation in rats

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12 December 2020

Dopamine-derived 1-methyl-6,7-dihydroxyisoquinolines as hydroxyl radical promoters and scavengers in the rat brain: in vivo and in vitro studies

1 reference

12 December 2020

Time course of nigrostriatal degeneration in parkinson's disease. A detailed study of influential factors in human brain amine analysis

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12 December 2020

Noradrenaline depletion exacerbates MPTP-induced striatal dopamine loss in mice.

1 reference

12 December 2020

The non-competitive NMDA-receptor antagonist MK-801 prevents the massive release of glutamate and aspartate from rat striatum induced by 1-methyl-4-phenylpyridinium (MPP+).

1 reference

12 December 2020

Methamphetamine-induced neuronal damage: a possible role for free radicals

1 reference

12 December 2020

Formation of 6-hydroxydopamine in caudate nucleus of the rat brain after a single large dose of methylamphetamine.

1 reference

12 December 2020

Correlation between brain dopamine levels and l-dopa activity in anti-Parkinson tests

1 reference

12 December 2020

Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse

1 reference

12 December 2020

Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on the regional distribution of brain monoamines in the rhesus monkey.

1 reference

12 December 2020

1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline, a new inhibitor of complex I

1 reference

12 December 2020

Striatal dopamine and homovanillic acid in Huntington's Disease

1 reference

12 December 2020

In vivo trapping of hydroxyl free radicals in the striatum utilizing intracranial microdialysis perfusion of salicylate: effects of MPTP, MPDP+, and MPP+

1 reference

12 December 2020

Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain

1 reference

12 December 2020

Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-Dopa in models of Parkinson's disease

1 reference

12 December 2020

GM1 gangliosides alter acute MPTP-induced behavioral and neurochemical toxicity in mice

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12 December 2020

Are NMDA antagonistic properties relevant for antiparkinsonian-like activity in rats?--case of amantadine and memantine

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12 December 2020

Chronic effects of single intrastriatal injections of 6-hydroxydopamine or 1-methyl-4-phenylpyridinium studied by microdialysis in freely moving rats

1 reference

12 December 2020

Short-term and long-term effects of methamphetamine on biogenic amine metabolism in extra-striatal dopaminergic nuclei

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12 December 2020

Extrastriatal dopamine in symptomatic and asymptomatic rhesus monkeys treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 reference

12 December 2020

1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism.

1 reference

12 December 2020

Chemical evidence for 6-hydroxydopamine to be an endogenous toxic factor in the pathogenesis of Parkinson's disease

1 reference

12 December 2020

Haloperidol, catalepsy, and equilibrating functions in the rat: antagonistic interaction of clinging and labyrinthine righting reactions

1 reference

12 December 2020

Progressive changes in striatal dopaminergic markers, nigral volume, and rotational behavior following iron infusion into the rat substantia nigra

1 reference

12 December 2020

Autoradiographic study on dopamine uptake sites and their correlation with dopamine levels and their striata from patients with Parkinson disease, Alzheimer disease, and neurologically normal controls

1 reference

12 December 2020

Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys

1 reference

12 December 2020

Methamphetamine and dopamine neurotoxicity: differential effects of agents interfering with glutamatergic transmission

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12 December 2020

6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation

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12 December 2020

Effects of classical and novel agents in a MPTP-induced reversible model of Parkinson's disease

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12 December 2020

Vitamin E attenuates the toxic effects of 6-hydroxydopamine on free radical scavenging systems in rat brain

1 reference

12 December 2020

NMDA-dependent superoxide production and neurotoxicity.

1 reference

12 December 2020

Sites of the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the macaque monkey include the ventral tegmental area and the locus coeruleus.

1 reference

12 December 2020

Strain differences in systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice correlate best with monoamine oxidase activity at the blood-brain barrier

1 reference

12 December 2020

MK-801 fails to protect against the dopaminergic neuropathology produced by systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice or intranigral 1-methyl-4-phenylpyridinium in rats

1 reference

12 December 2020

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

1 reference

12 December 2020

The effect of repeated administration of methamphetamine on dopamine uptake sites in rat striatum.

1 reference

12 December 2020

Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease

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12 December 2020

Motor disturbance induced by tremorine and oxotremorine.

1 reference

12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in non-human primates is antagonized by pretreatment with nimodipine at the nigral, but not at the striatal level.

1 reference

12 December 2020

Further studies on the generation of hydrogen peroxide by 6-hydroxydopamine. Potentiation by ascorbic acid.

1 reference

12 December 2020

Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity

1 reference

12 December 2020

Influence of dopamine synthesis on methamphetamine-induced changes in striatal and adrenal tyrosine hydroxylase activity

1 reference

12 December 2020

Neurochemical and behavioural features induced by chronic low dose treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset: implications for Parkinson's disease?

1 reference

12 December 2020

Degeneration of nigrostriatal dopaminergic neurons increases iron within the substantia nigra: a histochemical and neurochemical study

1 reference

12 December 2020

Identification and quantification of 1,2,3,4-tetrahydro-beta-carboline, 2-methyl-1,2,3,4-tetrahydro-beta-carboline, and 6-methoxy-1,2,3,4-tetrahydro-beta-carboline as in vivo constituents of rat brain and adrenal gland

1 reference

12 December 2020

Infusion of iron into the rat substantia nigra: nigral pathology and dose-dependent loss of striatal dopaminergic markers.

1 reference

12 December 2020

Effect of 6-hydroxydopamine and some other compounds on the concentration of norepinephrine in the hearts of mice

1 reference

12 December 2020

Brain Peroxidase and Catalase in Parkinson Disease

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12 December 2020

Rapid ATP loss caused by methamphetamine in the mouse striatum: relationship between energy impairment and dopaminergic neurotoxicity.

1 reference

12 December 2020

Functional role of the nigro-neostriatal dopamine neurons

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12 December 2020

Parkinson's Disease: Activity of L-Dopa Decarboxylase in Discrete Brain Regions

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12 December 2020

Role for excitatory amino acids in methamphetamine-induced nigrostriatal dopaminergic toxicity.

1 reference

12 December 2020

Dopamine uptake inhibitory capacities of beta-carboline and 3,4-dihydro-beta-carboline analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) oxidation products.

1 reference

12 December 2020

Reactive oxygen species and the central nervous system

1 reference

12 December 2020

The catalepsy test: its ups and downs

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12 December 2020

Intranigral iron injection induces behavioral and biochemical "parkinsonism" in rats

1 reference

12 December 2020

Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain

1 reference

12 December 2020

Dopamine-derived alkaloids in alcoholism and in Parkinson's and Huntington's diseases

1 reference

12 December 2020

The AMPA receptor antagonist NBQX does not alter the motor response induced by selective dopamine agonists in MPTP-treated monkeys

1 reference

12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitro

1 reference

12 December 2020

Intranigral injected iron progressively reduces striatal dopamine metabolism

1 reference

12 December 2020

Decreased catecholamines in the adrenal medulla of patients with parkinsonism

1 reference

12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian syndrome in Macaca fascicularis: which midbrain dopaminergic neurons are lost?

1 reference

12 December 2020

Hypokinesia produced by anterolateral hypothalamic 6-hydroxydopamine lesions and its reversal by some antiparkinson drugs

1 reference

12 December 2020

Biochemical and immunocytochemical changes induced by intrastriatal 6-hydroxydopamine injection in the rat nigrostriatal dopamine neuron system: evidence for cell death in the substantia nigra

1 reference

12 December 2020

Neurochemical lesioning in the rat brain with iontophoretic injection of the 1-methyl-4-phenylpyridinium ion (MPP+)

1 reference

12 December 2020

Dopamine-glutamate interactions in methamphetamine-induced neurotoxicity

1 reference

12 December 2020

Effect of oxidative stress on excitatory amino acid release by cerebral cortical synaptosomes

1 reference

12 December 2020

The evolution and distribution of morphological changes in the nervous system of the common marmoset following the acute administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

Secondary (toxic) parkinsonism as model of Parkinson's disease

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12 December 2020

Marked locomotor stimulation in monoamine-depleted mice following treatment with atropine in combination with clonidine

1 reference

12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by ethanol or acetaldehyde

1 reference

12 December 2020

1-Methyl-4-phenylpyridine (MPP+): regional dopamine neuron uptake, toxicity, and novel rotational behavior following dopamine receptor proliferation

1 reference

12 December 2020

Attenuation of methamphetamine-induced neurotoxicity in copper/zinc superoxide dismutase transgenic mice

1 reference

12 December 2020

Beta-carboline analogues of N-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): endogenous factors underlying idiopathic parkinsonism?

1 reference

12 December 2020

Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement

1 reference

12 December 2020

Long-term behavioural effects of TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline) after subchronic treatment in rats

1 reference

12 December 2020

Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice.

1 reference

12 December 2020

Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat.

1 reference

12 December 2020

Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies.

1 reference

12 December 2020

6-hydroxy-dopamine induced degeneration of central monoamine neurons

1 reference

12 December 2020

Effects of MPTP, MPP+ and paraquat on mitochondrial potential and oxidative stress

1 reference

12 December 2020

The neurotoxin MPTP does not reproduce in the rhesus monkey the interregional pattern of striatal dopamine loss typical of human idiopathic Parkinson's disease

1 reference

12 December 2020

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.

1 reference

12 December 2020

Absence of 6-hydroxydopamine in the rat brain after treatment with stimulants and other dopaminergic agents: a mass fragmentographic study

1 reference

12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate.

1 reference

12 December 2020

Increased iron in the substantia nigra compacta of the MPTP-lesioned hemiparkinsonian African green monkey: evidence from proton microprobe elemental microanalysis.

1 reference

12 December 2020

EPR kinetic studies of superoxide radicals generated during the autoxidation of 1-methyl-4-phenyl-2,3-dihydropyridinium, a bioactivated intermediate of parkinsonian-inducing neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

The MPTP-treated mouse as a model of parkinsonism: how good is it?

1 reference

12 December 2020

Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3,4-methylenedioxymethamphetamine.

1 reference

12 December 2020

Do NMDA receptor antagonists protect against MPTP-toxicity? Biochemical and immunocytochemical analyses in black mice

1 reference

12 December 2020

Biochemical lesions of the nigrostriatal system by TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline) and derivatives

1 reference

12 December 2020

Mechanisms of action of 6-hydroxydopamine

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12 December 2020

Acute effects of 1-methyl-1,4-phenylpyridinium ion (MPP+) on purine metabolism in rat striatum studied in vivo using the microdialysis technique

1 reference

12 December 2020

Extensive loss of brain dopamine and serotonin induced by chronic administration of MPTP in the marmoset.

1 reference

12 December 2020

Further treatment with MPTP does not produce parkinsonism in marmosets showing behavioural recovery from motor deficits induced by an earlier exposure to the toxin

1 reference

12 December 2020

Pharmacological characteristics of tremor, rigidity and hypokinesia induced by reserpine in rat.

1 reference

12 December 2020

Interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide. Inactivation of the enzyme

1 reference

12 December 2020

Long-term effect of MPTP in the mouse brain in relation to aging: neurochemical and immunocytochemical analysis.

1 reference

12 December 2020

Effect of D1 receptor stimulation in normal and MPTP monkeys

1 reference

12 December 2020

Antiparkinsonian actions of glutamate antagonists--alone and with L-DOPA: a review of evidence and suggestions for possible mechanisms.

1 reference

12 December 2020

Effect of 6-hydroxydopamine on brain norepinephrine and dopamine evidence for selective degeneration of catecholamine neurons

1 reference

12 December 2020

Toward an understanding of the molecular mechanisms of physiological cell death.

1 reference

12 December 2020

Biochemical and behavioral recovery in a rodent model of Parkinson's disease following stereotactic implantation of dopamine-containing liposomes.

1 reference

12 December 2020

Symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates: biochemical changes in striatal regions

1 reference

12 December 2020

Circling behavior in rats with partial, unilateral nigro-striatal lesions: Effect of amphetamine, apomorphine, and DOPA

1 reference

12 December 2020

Does an endogenous methylpyridinium analogue cause Parkinson's disease?

1 reference

12 December 2020

Role of dopamine in the neurotoxic effects of methamphetamine.

1 reference

12 December 2020

Determination of the (R)- and (S)-enantiomers of salsolinol and N-methylsalsolinol by use of a chiral high-performance liquid chromatographic column

1 reference

12 December 2020

Apoptosis and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons

1 reference

12 December 2020

Multiple methamphetamine injections induce marked increases in extracellular striatal dopamine which correlate with subsequent neurotoxicity

1 reference

12 December 2020

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

1 reference

12 December 2020

Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion

1 reference

12 December 2020

Pretreatment with nimodipine prevents MPTP-induced neurotoxicity at the nigral, but not at the striatal level in mice

1 reference

12 December 2020

Presence of tetrahydroisoquinoline and 2-methyl-tetrahydroquinoline in parkinsonian and normal human brains

1 reference

12 December 2020

The evolution of nigrostriatal neurochemical changes in the MPTP-treated squirrel monkey.

1 reference

12 December 2020

Effect of the NMDA antagonist MK-801 on MPTP-induced parkinsonism in the monkey

1 reference

12 December 2020

Tyrosine hydroxylase activity in caudate nucleus from Parkinson's disease: effects of iron and phosphorylating agents.

1 reference

12 December 2020

Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds

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12 December 2020

Sulfhydryl drugs reduce neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse.

1 reference

12 December 2020

Acute MPTP treatment produces no changes in mitochondrial complex activities and indices of oxidative damage in the common marmoset ex vivo one week after exposure to the toxin

1 reference

12 December 2020

Glutathione peroxidase activity in Parkinson's disease brain.

1 reference

12 December 2020

Stable parkinsonian syndrome and uneven loss of striatal dopamine fibres following chronic MPTP administration in baboons.

1 reference

12 December 2020

Influence of methamphetamine on nigral and striatal tyrosine hydroxylase activity and on striatal dopamine levels

1 reference

12 December 2020

Treatment with antioxidants does not prevent loss of dopamine in the striatum of MPTP-treated common marmosets: preliminary observations

1 reference

12 December 2020

Regional biotransformation of MPTP in the CNS of rodents and its relation to neurotoxicity

1 reference

12 December 2020

Complex I inhibitor effect on the nigral and striatal release of dopamine in the presence and absence of nomifensine.

1 reference

12 December 2020

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system.

1 reference

12 December 2020

N-methylation of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (R)-salsolinol, in rat brains: in vivo microdialysis study.

1 reference

12 December 2020

MPP+ and MPDP+ induced oxygen radical formation with mitochondrial enzymes.

1 reference

12 December 2020

Changes in lipid peroxidation induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium in mouse brain homogenates

1 reference

12 December 2020

Methamphetamine-induced changes in brain catecholamines in rats and guinea pigs

1 reference

12 December 2020

1 reference

12 December 2020

Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease.

1 reference

12 December 2020

In vivo monoamine oxidase inhibition by d-amphetamine

1 reference

12 December 2020

Striatal dopaminergic toxicity following intranigral injection in rats of 2-methyl-norharman, a beta-carbolinium analog of N-methyl-4-phenylpyridinium ion (MPP+).

1 reference

12 December 2020

Toxic effects of iron for cultured mesencephalic dopaminergic neurons derived from rat embryonic brains.

1 reference

12 December 2020

Molecular mechanisms for neurodegeneration. Synergism between reactive oxygen species, calcium, and excitotoxic amino acids.

1 reference

12 December 2020

Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in monkeys: a possible role for the locus coeruleus in the progression of Parkinson's disea

1 reference

12 December 2020

Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice

1 reference

12 December 2020

Salsolinol and catecholamines in human brain and their relation to alcoholism.

1 reference

12 December 2020

Evidence for mitochondrial dysfunction in Parkinson's disease--a critical appraisal

1 reference

12 December 2020

The role of environmental toxins in the etiology of Parkinson's disease

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12 December 2020

Dose-dependent destruction of the coeruleus-cortical and nigral-striatal projections by MPTP.

1 reference

12 December 2020

Effects of pargyline and pyrogallol on the methamphetamine-induced dopamine depletion

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12 December 2020

A new experimental model of hypokinesia.

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12 December 2020

A radical hypothesis for neurodegeneration

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12 December 2020

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12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

12 December 2020

Inhibition of mitochondrial succinate oxidation—Similarities and differences between N-methylated β-carbolines and MPP+

1 reference

12 December 2020

The protective effect of 1-tert.butyl-4,4-diphenylpiperidine against the nigrostriatal neurodegeneration caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

Chronic administration of MPTP to monkeys: behavioural morphological and biochemical correlates

1 reference

12 December 2020

Long-term methamphetamine induced changes in brain catecholamines in tolerant rhesus monkeys.

1 reference

12 December 2020

Studies of the potentially endogenous toxin TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline) in neuronal and glial cell cultures

1 reference

12 December 2020

N-methyl-D-aspartate receptor antagonist MK-801 induced circling behavior in rats with unilateral striatal ischemic lesions or nigral 6-hydroxydopamine lesions.

1 reference

12 December 2020

Fate of nigrostriatal neurons in young mature mice given 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a neurochemical and morphological reassessment.

1 reference

12 December 2020

The pharmacology of (-)deprenyl

1 reference

12 December 2020

Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system

1 reference

12 December 2020

Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-Hydroxydopamine

1 reference

12 December 2020

Mitochondrial respiratory inhibition by N-methylated beta-carboline derivatives structurally resembling N-methyl-4-phenylpyridine

1 reference

12 December 2020

Long-term effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: a regional study

1 reference

12 December 2020

MPTP-induced parkinsonism

1 reference

12 December 2020

The neurochemistry of Parkinson's disease: effect of L-dopa therapy

1 reference

12 December 2020

The competitive NMDA antagonist CPP protects substantia nigra neurons from MPTP-induced degeneration in primates

1 reference

12 December 2020

Dissociation between biochemical and behavioral recovery in MPTP-treated mice

1 reference

12 December 2020

The TaClo concept: 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo), a new toxin for dopaminergic neurons.

1 reference

12 December 2020

The competitive NMDA antagonist CGP40.116 enhances L-dopa response in MPTP-treated marmosets

1 reference

12 December 2020

Novel toxins and Parkinson's disease: N-methylation and oxidation as metabolic bioactivation of neurotoxin.

1 reference

12 December 2020

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

1 reference

12 December 2020

Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations

1 reference

12 December 2020

Interactions of the neurotoxin MPTP and its demethylated derivative (PTP) with monoamine oxidase-B

1 reference

12 December 2020

Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease

1 reference

12 December 2020

4-Phenylpyridine (4PP) and MPTP: the relationship between striatal MPP+ concentrations and neurotoxicity

1 reference

12 December 2020

Effects of repeated administration of a high dose of methamphetamine on dopamine and glutamate release in rat striatum and nucleus accumbens.

1 reference

12 December 2020

1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-MPTP) is less neurotoxic than MPTP in the common marmoset

1 reference

12 December 2020

Effects of 6-hydroxydopamine on catecholamine containing neurones in the rat brain

1 reference

12 December 2020

A selective increase in particulate superoxide dismutase activity in parkinsonian substantia nigra

1 reference

12 December 2020

Selective lesion of the nigrostriatal dopaminergic pathway by MPTP and acetaldehyde or diethyldithiocarbamate

1 reference

12 December 2020

Developing a stable bilateral model of parkinsonism in rhesus monkeys

1 reference

12 December 2020

Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes

1 reference

12 December 2020

Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine

1 reference

12 December 2020

NBQX (6-nitro-sulfamoyl-benzo-quinoxaline-dione) and CPP (3-carboxy- piperazin-propyl phosphonic acid) potentiate dopamine agonist induced rotations in substantia nigra lesioned rats

1 reference

12 December 2020

Decreased dopamine in the retinas of patients with Parkinson's disease

1 reference

12 December 2020

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

1 reference

12 December 2020

The neuropathologic basis of different clinical subgroups of Parkinson's disease.

1 reference

12 December 2020

Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity

1 reference

12 December 2020

In vivo measurement of extracellular dopamine and DOPAC in rat striatum after various dopamine-releasing drugs; implications for the origin of extracellular DOPAC.

1 reference

12 December 2020

On stereotypy and catalepsy: studies on the effect of amphetamines and neuroleptics in rats

1 reference

12 December 2020

The relationships between aging, monoamine oxidase, striatal dopamine and the effects of MPTP in C57BL/6 mice: a critical reassessment

1 reference

12 December 2020

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

1 reference

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Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.

1 reference

12 December 2020

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1 reference

12 December 2020

Morphine versus haloperidol catalepsy in the rat: a behavioral analysis of postural support mechanisms.

1 reference

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Neurochemical and behavioral effects of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) in rat, guinea pig, and monkey

1 reference

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CNS Modulation of adrenal tyrosine hydroxylase in Parkinson's disease and metabolic encephalopathies

1 reference

12 December 2020

Iron induces degeneration of nigrostriatal neurons

1 reference

12 December 2020

Effect of clonidine and atropine on rest tremor in the MPTP monkey model of parkinsonism

1 reference

12 December 2020

Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

1 reference

12 December 2020

Inhibition of mitochondrial complexes I and IV by 6-hydroxydopamine

1 reference

12 December 2020

Effects of Brain-derived Neurotrophic Factor on 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in Monkeys

1 reference

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Correlation between 1-methyl-4-phenylpyridinium ion (MPP+) levels, ascorbic acid oxidation and glutathione levels in the striatal synaptosomes of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated rat

1 reference

12 December 2020

Tremor produced by Drugs

1 reference

12 December 2020

Neuroprotective effects of alpha-dihydroergocryptine against damages in the substantia nigra caused by severe treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1 reference

12 December 2020

Vitamin E attenuates the toxic effects of intrastriatal injection of 6-hydroxydopamine (6-OHDA) in rats: behavioral and biochemical evidence

1 reference

12 December 2020

Neuropeptide levels in the basal ganglia of aged common marmosets following prolonged treatment with MPTP.

1 reference

12 December 2020

Pathology of Parkinson's disease. Changes other than the nigrostriatal pathway

1 reference

12 December 2020

Dopamine receptor changes in untreated and (+)-PHNO-treated MPTP parkinsonian primates

1 reference

12 December 2020

Neurotoxic Sesquiterpenoids from the Yellow Star ThistleCentaurea solstitialis L. (Asteraceae)

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/HLCA.19910740114

Identifiers

DOI

10.1007/BF01291788

1 reference

PubMed ID

9013391

Dimensions Publication ID

29 September 2017

0 references

1 reference

PubMed ID

9013391